Mitemcinal (GM-611), an orally active motilin receptor agonist, improves delayed gastric emptying in a canine model of diabetic gastroparesis

Clinical and Experimental Pharmacology and Physiology

Volumn 35, Issue 7, 2008, Pages 788-796

  Onoma, Mitsu ^a   Ozaki, Ken Ichi ^a   Yogo, Kenji ^a   Monnai, Makoto ^b   Muramatsu, Hiroyasu ^a   Kamei, Kenshi ^a   Kawabe, Yoshiki ^a   Hayashi, Shuji ^a   Shiga, Toshihiko ^b   Matsuo, Saori ^a   Suzuki, Masami ^a   Itoh, Zen ^c   Omura, Satoshi ^a   Takanashi, Hisanori ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b Chugai Research Institute for Medical Science Inc   (Japan)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

Cisapride; Diabetic gastroparesis; Dog; Gastric emptying; Gastrointestinal motility; GM 611; Mitemcinal

Indexed keywords

ALLOXAN; CISAPRIDE; MITEMCINAL; MOTILIN; PARACETAMOL; PROKINETIC AGENT; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DOG; DOSE RESPONSE; DRUG ABSORPTION; DRUG EFFECT; FEMALE; GASTROINTESTINAL MOTILITY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN TREATMENT; NERVE CONDUCTION; NERVE FUNCTION; NONHUMAN; STOMACH EMPTYING; STOMACH PARESIS; TIBIAL NERVE; VAGUS NERVE;

ADMINISTRATION, ORAL; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DOGS; ERYTHROMYCIN; FEMALE; GASTRIC EMPTYING; GASTROPARESIS; RECEPTORS, GASTROINTESTINAL HORMONE; RECEPTORS, NEUROPEPTIDE;

EID: 44249100932     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2008.04924.x     Document Type: Article

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