Pharmacokinetics of antofloxacin hydrochloride, a new fluoroquinolone antibiotic, after single oral dose administration in Chinese healthy male volunteers

Biopharmaceutics and Drug Disposition

Volumn 29, Issue 3, 2008, Pages 167-172

  Xiao, Yonghong ^a   Lu, Yuan ^a   Kang, Zisheng ^a   Zhang, Ming ^a   Liu, Yan ^a   Zhang, Man ^a   Li, Tianyun ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Antofloxacin hydrochloride; Chinese health male volunteers; Pharmacokinetics; Single dose

Indexed keywords

ANTOFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ABSENCE OF SIDE EFFECTS; ADULT; AREA UNDER THE CURVE; ARTICLE; CHINESE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; DRUG URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LABORATORY TEST; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ADULT; ANTI-BACTERIAL AGENTS; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; HALF-LIFE; HUMANS; MALE; OFLOXACIN; TISSUE DISTRIBUTION;

EID: 44249096110     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.600     Document Type: Article

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