Naturally occurring isotopes of an analyte can interfere with doubly deuterated internal standard measurement

Annals of Clinical Biochemistry

Volumn 45, Issue 2, 2008, Pages 210-212

  Duxbury, K ^a   Owen, L ^a   Gillingwater, S ^b   Keevil, B ^a  

^a MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^b Waters Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; HYDROCORTISONE; ISOTOPE;

ARTICLE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEASUREMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STANDARD; TANDEM MASS SPECTROMETRY;

DEUTERIUM; HYDROCORTISONE; ISOTOPES; MASS SPECTROMETRY; REFERENCE STANDARDS;

EID: 44249089969     PISSN: 00045632     EISSN: 00045632     Source Type: Journal    
DOI: 10.1258/acb.2007.007137     Document Type: Article

References (3)

1. Stokvis E, Rosing H, Beijnen JH. Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not? Rapid Commun Mass Spectrom 2005;19:401-7
2. Wear JE, Owen LJ, Duxbury KJ, Keevil BG. A simpli.ed method for the measurement of urinary free cortisol using LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2007;858:27-31
3. Tai SS, Welch MJ. Development and evaluation of a candidate reference method for the determination of total cortisol in human serum using isotope dilution liquid chromatography/mass spectrometry and liquid chromatography/ tandem mass spectrometry. Anal Chem 2004;76:1008-14