Responses of differentiated MC3T3-E1 osteoblast-like cells to reactive oxygen species

European Journal of Pharmacology

Volumn 587, Issue 1-3, 2008, Pages 35-41

  Fatokun, Amos A ^a   Stone, Trevor W ^a   Smith, Robert A ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Cell death; Kynurenines; Mitochondrial poisons; Osteoblasts; Oxidative stress

Indexed keywords

3 HYDROXYANTHRANILIC ACID; 3 HYDROXYKYNURENINE; 3 NITROPROPIONIC ACID; CATALASE; COPPER ION; CYCLOSPORIN A; HYDROGEN PEROXIDE; MANNITOL; N ACETYL S NITROSOPENICILLAMINE; NICOTINAMIDE; POTASSIUM CYANIDE; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE DISMUTASE; TRYPTOPHAN; XANTHINE; XANTHINE OXIDASE;

ANIMAL CELL; ARTICLE; BONE CELL; CELL CULTURE; CELL DAMAGE; CELL DEATH; CELL DIFFERENTIATION; CELL PROTECTION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; GLYCOLYSIS; MITOCHONDRION; MOUSE; NONHUMAN; OSTEOBLAST; OXIDATIVE STRESS; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; TRYPTOPHAN METABOLISM;

3T3 CELLS; ANIMALS; APOPTOSIS; CASPASES; CELL DIFFERENTIATION; CELL SURVIVAL; COLORING AGENTS; COPPER; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; IMMUNOSUPPRESSIVE AGENTS; MICE; MICE, INBRED C57BL; NECROSIS; NITRIC OXIDE DONORS; OSTEOBLASTS; OXAZINES; OXIDANTS; OXIDATIVE STRESS; POISONS; REACTIVE OXYGEN SPECIES; XANTHENES;

EID: 44149092831     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.03.024     Document Type: Article

References (38)

1. Arai M., Shibata Y., Pugdee K., Abiko Y., and Ogata Y. Effects of reactive oxygen species (ROS) on antioxidant system and osteoblastic differentiation in MC3T3-E1 cells. IUBMB Life 59 (2007) 27-33
2. Basu S., Michaelsson K., Olofsson H., Johansson S., and Melhus H. Association between oxidative stress and bone mineral density. Biochem. Biophys. Res. Commun. 288 (2001) 275-279
3. Bhangu P.S., Genever P.G., Spencer G.J., Grewal T.S., and Skerry T.M. Evidence for targeted vesicular glutamate exocytosis in osteoblasts. Bone 29 (2001) 16-23
4. Burdon R.H. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic. Biol. Med. 18 (1995) 775-794
5. Chodimella R., Anderson J., Hong Y., and Bishop A. Nitric oxide (NO) sensitivity and differentiation status in motor neurons (abstract) (2005), Society for Neuroscience, Washington, DC Program No. 599.2. 2005 Abstract Viewer/Itinerary Planner (on-line)
6. Dawson V.L., and Dawson T.M. Deadly conversations: nuclear-mitochondrial cross-talk. J. Bioenerg. Biomembranes 36 (2004) 287-294
7. Dreher I., Schuetze N., Baur A., Hesse K., Schneider D., Koehrle J., and Jakob F. Selenoproteins are expressed in fetal human osteoblast-like cells. Biochem. Biophys. Res. Commun. 245 (1998) 101-107
8. Eastman C.L., and Guilarte T.R. The role of hydrogen peroxide in the in vitro cytotoxicity of 3-hydroxykynurenine. Neurochem. Res. 15 (1990) 1101-1107
9. Fatokun A.A., Stone T.W., and Smith R.A. Hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells: the effects of glutamate and protection by purines. Bone 39 (2006) 542-551
10. Fatokun A.A., Stone T.W., and Smith R.A. Cell death in rat cerebellar granule neurons induced by hydrogen peroxide in vitro: mechanisms and protection by adenosine receptor ligands. Brain Res. 1132 (2007) 193-202
11. Fatokun A.A., Stone T.W., and Smith R.A. Hydrogen peroxide mediates damage by xanthine and xanthine oxidase in cerebellar granule neuronal cultures. Neurosci. Lett. 416 (2007) 34-38
12. Forrest C.M., Mackay G.M., Oxford L., Stoy N., Stone T.W., and Darlington L.G. Kynurenine pathway metabolism in patients with osteoporosis after two years of drug treatment. Clin. Exp. Pharmacol. Physiol. 33 (2005) 1078-1087
13. Franceschi R.T., and Iyer B.S. Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells. J. Bone Miner. Res. 7 (1992) 235-246
14. Gilad E., Zingarelli B., Salzman A.L., and Szabo C. Protection by inhibition of Poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts in vitro. J. Mol. Cell. Cardiol. 29 (1997) 2585-2597
15. Goldstein L.E., Leopold M.C., Huang X., Atwood C.S., Saunders A.J., Hartshorn M., Lim J.T., Faget K.Y., Muffat J.A., Scarpa R.C., Chylack L.T., Bowden E.F., Tanzi R.E., and Bush A.I. 3-hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote αcrystallin cross-linking by metal ion reduction. Biochemistry 39 (2000) 7266-7275
16. Halliwell B. Reactive oxygen species and the central nervous system. J. Neurochem. 59 (1992) 1609-1623
17. Harada S., Matsumoto T., and Ogata E. Role of ascorbic acid in the regulation of proliferation in osteoblast-like MC3T3-E1 cells. J. Bone Miner. Res. 6 (1991) 903-908
18. Isomura H., Fujie K., Shibata K., Inoue N., Iizuka T., Takebe G., Takahashi K., Nishihira J., Izumi H., and Sakamoto W. Bone metabolism and oxidative stress in postmenopausal rats with iron overload. Toxicology 197 (2004) 93-100
19. Iwahashi H., Ishii T., Sugata R., and Kido R. Superoxide dismutase enhances the formation of hydroxyl radicals in the reaction of 3-hydroxyanthranilic acid with molecular oxygen. Biochem. J. 251 (1988) 893-899
20. Maggio D., Barabani M., Pierandrei M., Polidori M.C., Catani M., Mecocci P., Senin U., Pacifici R., and Cherubini A. Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional study. J. Clin. Endocrinol. Metab. 88 (2003) 1523-1527
21. Mancini L., Moradi-Bidhendi N., Becherini L., Martineti V., and MacIntyre I. The biphasic effects of nitric oxide in primary rat osteoblasts are cGMP dependent. Biochem. Biophys. Res. Commun. 274 (2000) 477-481
22. Muthusami S., Ramachandran H., Muthusamy B., Vasudevan G., Prabhu V., Subramaniam V., Jagadeesan A., and Narasimhan S. Ovariectomy induces oxidative stress and impairs bone antioxidant system in adult rats. Clin. Chim. Acta 360 (2005) 81-86
23. Nordberg J., and Arnér E.S.J. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic. Biol. Med. 31 (2001) 1287-1312
24. Pereira R.M., Delany A.M., and Canalis E. Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture. Bone 28 (2001) 484-490
25. Quarles L.D., Yohay D.A., Lever L.W., Caton R., and Wenstrup R.J. Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: an in vitro model of osteoblast development. J. Bone Min. Res. 7 (1992) 683-690
26. Repine J.E., Eaton J.W., Anders M.W., Hoidal J.R., and Fox R.B. Generation of hydroxyl radical by enzymes, chemicals, and human phagocytes in vitro. Detection with the anti-inflammatory agent, dimethyl sulfoxide. J. Clin. Invest. 64 (1979) 1642-1651
27. 1 receptor responses by nitric oxide and superoxide in rat hippocampus. Eur. J. Neurosci. 20 (2004) 719-728
28. Smith A.J., Stone T.W., and Smith R.A. Neurotoxicity of tryptophan metabolites. Biochem. Soc. Trans. 35 (2007) 1287-1289
29. Stone T.W. Kynurenines in the CNS: from endogenous obscurity to therapeutic importance. Prog. Neurobiol. 64 (2001) 185-218
30. Stone T.W., and Darlington L.G. Endogenous kynurenines as targets for drug discovery and development. Nat. Rev. Drug Discov. 1 (2002) 609-620
31. Sudo H., Kodama H., Amagai Y., Yamamoto S., and Kasai S. In vitro differentiation and calcification in new clonal osteogenic cell line derived from newborn mouse calvariae. J. Cell Biol. 96 (1983) 191-198
32. Tronov V.A., Konstantinov E.M., Petrakou E., Tsilimigaki S., and Piperakis S.M. Nicotinamide "protects" resting lymphocytes exposed to hydrogen peroxide from necrosis but not from apoptosis. Cell Biol. Toxicol. 18 (2002) 359-367
33. Varadharaj S., Watkins T., Cardounel A.J., Garcia J.G., Zweier J.L., Kuppusamy P., Natarajan V., and Parinandi N.L. Vitamin C-induced loss of redox-dependent viability in lung microvascular endothelial cells. Antioxid. Redox Signal. 7 (2005) 287-300
34. Wei H., Leeds P., Chen R.-W., Wei W., Leng Y., Bredsen D.E., and Chuang D.-M. Neuronal apoptosis induced by pharmacological concentrations of 3-hydroxykynurenine: characterisation and protection by dantrolene and Bcl-2 overexpression. J.Neurochem. 75 (2000) 81-90
35. Wilkinson J.A., Scragg J.L., Boyle J.P., Nilius B., and Peers C. H2O2-stimulated CA2+ influx via TRPM2 is not the sole determinant of subsequent cell death. Pflugers Arch.-Eur. J. Physiol. 455 (2008) 1141-1151
36. Yalin S., Bagis S., Aksit S.C., Arslan H., and Erdogan C. Effect of free radicals and antioxidants on postmenopausal osteoporosis. Asian J. Chem. 18 (2006) 1091-1096
37. Yang S., Madyastha P., Bingel S., Ries W., and Key L. A new superoxide-generating oxidase in murine osteoclasts. J. Biol. Chem. 276 (2001) 5452-5458
38. Zalavras C., Shah S., Birnbaum M.J., and Frenkel B. Role of apoptosis in glucocorticoid-induced osteoporosis and osteonecrosis. Crit. Rev. Eukaryot. Gene Expr. 13 (2003) 221-235