Role of epsin 1 in synaptic vesicle endocytosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 17, 2008, Pages 6445-6450

  Jakobsson, Joel ^a   Gad, Helge ^a,b   Andersson, Fredrik ^a   Löw, Peter ^a   Shupliakov, Oleg ^a   Brodin, Lennart ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Adaptor; Amphiphysin; AP2; Clathrin; ENTH domain

Indexed keywords

CLATHRIN; EPSIN; EPSIN 1; ANTIBODY; VESICULAR TRANSPORT ADAPTOR PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL MEMBRANE; CELL VACUOLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENDOCYTOSIS; LAMPREY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; RETICULOSPINAL TRACT; SYNAPSE VESICLE; ANIMAL; CHEMISTRY; COATED PIT; METABOLISM; MICROINJECTION; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SYNAPSE; ULTRASTRUCTURE;

PETROMYZONTIDAE;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTIBODIES; COATED PITS, CELL-MEMBRANE; ENDOCYTOSIS; LAMPREYS; MICROINJECTIONS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SYNAPSES; SYNAPTIC VESICLES;

EID: 44049105354     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0710267105     Document Type: Article

References (32)

1. Jung N, Haucke V (2007) Clathrin-mediated endocytosis at synapses. Traffic 8:1129-1136.
2. Ungewickell EJ, Hinrichsen L (2007) Endocytosis: Clathrin-mediated membrane budding. Curr Opin Cell Biol 19:417-425.
3. Schmid EM, McMahon HT (2007) Integrating molecular and network biology to decode endocytosis. Nature 448:883-888.
4. Traub LM (2003) Sorting it out: AP-2 and alternate clathrin adaptors in endocytic cargo selection. J Cell Biol 163:203-208.
5. Diril MK, Wienisch M, Jung N, Klingauf J, Haucke V (2006) Stonin 2 is an AP-2-dependent endocytic sorting adaptor for synaptotagmin internalization and recycling. Dev Cell 10:233-244.
6. Itoh T, De Camilli P (2006) BAR, F-BAR (EFC), and ENTH/ANTH domains in the regulation of membrane-cytosol interfaces and membrane curvature. Biochim Biophys Acta 1761:897-912.
7. Zhang B, et al. (1998) Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis. Neuron 21:1465-1475.
8. Nonet ML, et al. (1999) UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles. Mol Biol Cell 10:2343-2360.
9. Ford MG, et al. (2001) Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes. Science 291:1051-1055.
10. Chen H, et al. (1998) Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis. Nature 394:793-797.
11. Legendre-Guillemin V, Wasiak S, Hussain NK, Angers A, McPherson PS (2004) ENTH/ANTH proteins and clathrin-mediated membrane budding. J Cell Sci 117:9-18.
12. Oldham CE, Mohney RP, Miller SL, Hanes RN, O'Bryan JP (2002) The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination. Curr Biol 12:1112-1116.
13. Polo S, et al. (2002) A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins. Nature 416:451-455.
14. Ford MG, et al. (2002) Curvature of clathrin-coated pits driven by epsin. Nature 419:361-366.
15. Brodin L, Shupliakov O (2006) Giant reticulospinal synapse in lamprey: Molecular links between active and periactive zones. Cell Tissue Res 326:301-310.
16. Schmid EM, et al. (2006) Role of the AP2 β-appendage hub in recruiting partners for clathrin-coated vesicle assembly. PLoS Biol 4:e262.
17. 2+-triggered synaptic vesicle exocytosis and clathrin-mediated endocytosis at a central synapse. Neuron 21:607-616.
18. Ringstad N, et al. (1999) Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis. Neuron 24:143-154.
19. Evergren E, et al. (2004) Amphiphysin is a component of clathrin coats formed during synaptic vesicle recycling at the lamprey giant synapse. Traffic 5:514-528.
20. Zoncu R, et al. (2007) Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci USA 104:3793-3798.
21. Rappoport JZ, Kemal S, Benmerah A, Simon SM (2006) Dynamics of clathrin and adaptor proteins during endocytosis. Am J Physiol 291:C1072-C1081.
22. Itoh T, et al. (2001) Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis. Science 291:1047-1051.
23. Vanden Broeck D, De Wolf MJ (2006) Selective blocking of clathrin-mediated endocytosis by RNA interference: Epsin as target protein. BioTechniques 41:475-484.
24. Deinhardt K, Berninghausen O, Willison HJ, Hopkins CR, Schiavo G (2006) Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. J Cell Biol 174:459-471.
25. Hinrichsen L, Meyerholz A, Groos S, Ungewickell EJ (2006) Bending a membrane: How clathrin affects budding. Proc Natl Acad Sci USA 103:8715-8720.
26. Di Paolo G, et al. (2002) Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron 33:789-804.
27. Hawryluk MJ, et al. (2006) Epsin 1 is a polyubiquitin-selective clathrin-associated sorting protein. Traffic 7:262-281.
28. Andersson F, Jakobsson J, Löw P, Shupliakov O, Brodin L (2008) Perturbation of syndapin/PACSIN impairs synaptic vesicle recycling evoked by intense stimulation. J Neurosci, in press.
29. Royle SJ, Lagnado L (2003) Endocytosis at the synaptic terminal. J Physiol (London) 553:345-355.
30. Di Paolo G, De Camilli P (2003) Does clathrin pull the fission trigger? Proc Natl Acad Sci USA 100:4981-4983.
31. Aguilar RC, et al. (2006) Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Proc Natl Acad Sci USA 103:4116-4121.
32. Evergren E, et al. (2004) A pre-embedding immunogold approach for detection of synaptic endocytic proteins in situ. J Neurosci Methods 135:169-174.