Persistent lactic acidosis in neonatal hypoxic-ischaemic encephalopathy correlates with EEG grade and electrographic seizure burden

Archives of Disease in Childhood: Fetal and Neonatal Edition

Volumn 93, Issue 3, 2008, Pages

  Murray, D M ^a,c   Boylan, G B ^a   Fitzgerald, A P ^a   Ryan, C A ^a   Murphy, B P ^a   Connolly, S ^b  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^c University College Cork and INFANT Centre   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

LACTIC ACID;

ARTICLE; BASE DEFICIT; BLOOD PH; BRAIN ISCHEMIA; CLINICAL ARTICLE; CORRELATION ANALYSIS; DISEASE COURSE; DISEASE SEVERITY; DISORDERS OF ACID BASE BALANCE; ELECTROENCEPHALOGRAM; ELECTROGRAPHIC SEIZURE BURDEN; FEMALE; HUMAN; LACTATE BLOOD LEVEL; LACTIC ACIDOSIS; MALE; NEWBORN; NEWBORN HYPOXIA; NEWBORN MONITORING; PARAMETER; PREDICTION; PRIORITY JOURNAL; SEIZURE; TERM BIRTH; TIME; VIDEORECORDING; BLOOD; ELECTROENCEPHALOGRAPHY; HOSPITALIZATION; METHODOLOGY; MONITORING; PROGNOSIS; PROSPECTIVE STUDY;

ACIDOSIS, LACTIC; ASPHYXIA NEONATORUM; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; INFANT, NEWBORN; LACTIC ACID; MALE; MONITORING, PHYSIOLOGIC; PROGNOSIS; PROSPECTIVE STUDIES; SEIZURES; SEVERITY OF ILLNESS INDEX; TIME FACTORS; VIDEO RECORDING;

EID: 44049101536     PISSN: 13592998     EISSN: 14682052     Source Type: Journal    
DOI: 10.1136/adc.2006.100800     Document Type: Article

References (26)

1. Vannucci RC. Hypoxic-ischaemic encephalopathy. Am J Perinatol 2000;17:113-20.
2. Pezzani C, Radvanyi-Bouvet MF, Relier JP, et al. Neonatal electroencephalography during the first twenty-four hours of life in full-term newborn infants. Neuropediatrics 1986;17:11-8.
3. van Lieshaut HBM, Jacobs JWFM, Rotteveel JJ, et al. The prognostic value of the EEG in asphyxiated newborns. Acta Neurol Scand 1995;91:203-7.
4. Huang CC, Wang ST, Chang YC, et al. Measurement of the urinary:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy. N Engl J Med 1999;341:328- 33.
5. da Silva S, Hennebert N, Denis R, et al. Clinical value of single lactate measurement after intrapartum asphyxia. Acta Paediatr 2000;89:320-3.
6. Ikeda T, Murata Y, Quilligan EJ, et al. Foetal heart rate patterns in postasphyxiated foetal lambs with brain damage. Am J Obstet Gynecol 1998;179:1330-7.
7. Yildizdas D, Yapicioglu H, Yilmaz HL, et al. Correlation of simultaneously obtained capillary, venous, and arterial blood gases of patients in a paediatric intensive care unit. Arch Dis Child 2004;89:176- 80.
8. Johnson KJ, Cress GA, Connolly NW, et al. Neonatal laboratory blood sampling: comparision of results from arterial catheters with those from an automated capillary device. Neonatal Netw 2000;19:27-34.
9. Amiel-Tison C. Update of the Amiel-Tison neurologic assessment for the term neonate or at 40 weeks corrected age. Pediatr Neurol 2002;27:196-202
10. Pressler RM, Boylan GB, Morton M, et al. Early serial EEG in hypoxic ischaemic encephalopathy. Clin Neurophysiol 2001;112:31-7.
11. Sarnat HB, Sarnat MS. Neonatal encephalopathy following foetal distress a clinical and electroencephalographic study. Arch Neurol 1976;33:695-706.
12. Clancy RR, Legido A. The exact ictal and interictal duration of electroencephalographic neonatal seizures. Epilepsia 1987;28:537- 41.
13. Scher MS. Ictal and interictal electrographic seizure durations in preterm and term neonates. Epilepsia 1993;34:284-8.
14. Shah S, Tracy M, Smyth J. Postnatal lactate as an early predictor of short-term outcome after intrapartum asphyxia. J Perinatol 2004;24:16-20.
15. Fernandez F, Verdu A, Quero J, et al. Cerebrospinal fluid lactate levels in term infants with perinatal hypoxia. Pediatr Neurol 1986;2:39-42.
16. Hanrahan JD, Cox IJ, Azzopardi D, et al. Relation between proton magnetic resonance spectroscopy within 18 hours of birth asphyxia and neurodevelopment at 1 year of age. Dev Med Child Neurol 1999;41:76-82.
17. Hanrahan JD, Cox IJ, Edwards AD, et al. Persistent increases in cerebral lactate concentration after birth asphyxia. Pediatr Res 1998;44:304-11.
18. Lipka K, Bulow H. Lactic acidosis following convulsions. Acta Anaesth Scand 2003;47:616-8.
19. Botion LM, Doretto MC. Changes in peripheral energy metabolism during audiogenic seizures in rats. Physiol Behav 2003;78:535-41.
20. Comford EM, Shamsa K, Zeitzer JM, et al. Regional analyses of CNS microdialyslate glucose and lactate in seizure patients. Epilepsia 2002;43:1360-71.
21. Yager JY, Armstrong EA, Mujashita H, et al. Prolonged neonatal seizures exacerbate hypoxic-ischaemic brain damage: correlation with cerebral energy metabolism and excitatory amino acid release. Dev Neurosci 2002;24:367-81.
22. Kreisberg RA. Lactate homeostasis and lactic acidosis. Ann Intern Med 1980;92(Pt 1):227-37.
23. Stacpoole PW, Wright EC, Baumgartner TG, et al. Natural history and course of acquired lactic acidosis in adults. DCA-Lactic Acidosis Study Group. Am J Med 1994;97:47-54.
24. Ando M, Shimizu K. Acute renal failure with lactic acidosis. Nippon Jinzo Gakkai Shi 1990;32:729-37.
25. Clancy RR, Legido A, Lewis D. Occult neonatal seizures. Epilepsia 1988;29:256-61
26. Bye AM, Flanagan D. Spatial and temporal characteristics of neonatal seizures. Epilepsia 1995;36:1009-16.