Streptomyces phospholipase D mutants with altered substrate specificity capable of phosphatidylinositol synthesis

ChemBioChem

Volumn 9, Issue 6, 2008, Pages 974-981

  Masayama, Atsushi ^a   Takahashi, Tetsuya ^a   Tsukada, Kaori ^a   Nishikawa, Seigo ^a   Takahashi, Rie ^a   Adachi, Masaatsu ^a   Koga, Kazushi ^a   Suzuki, Atsuo ^a   Yamane, Takashi ^a   Nakano, Hideo ^a   Iwasaki, Yugo ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Enzymes; High throughput screening; Molecular evolution; Phosphatidylinositol; Phospholipases

Indexed keywords

CYCLOHEXANOL; INOSITOL; MUTANT PROTEIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE D; 1,2 OLEOYLPHOSPHATIDYLCHOLINE; 1,2-OLEOYLPHOSPHATIDYLCHOLINE;

ARTICLE; BACTERIUM COLONY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE EXPRESSION; GENE MUTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; LIPID ANALYSIS; LIPID HYDROLYSIS; LIPOGENESIS; MASS SPECTROMETRY; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STREPTOMYCES ANTIBIOTICUS; WILD TYPE; BINDING SITE; BIOSYNTHESIS; CHEMICAL STRUCTURE; ENZYMOLOGY; GENETICS; HYDROLYSIS; KINETICS; METABOLISM; MUTATION; PROTEIN CONFORMATION;

ESCHERICHIA COLI; STREPTOMYCES; STREPTOMYCES ANTIBIOTICUS;

BINDING SITES; HYDROLYSIS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASE D; PROTEIN CONFORMATION; STREPTOMYCES ANTIBIOTICUS; SUBSTRATE SPECIFICITY;

EID: 44049099107     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200700528     Document Type: Article

References (44)

1. a) Y. Iwasaki, T. Yamane in Lipid Biotechnology (Eds.: T M. Kuo, H. W. Gardner), Marcel Dekker, New York, 2002, pp. 417-431;
2. b) P. D'Arrigo, S. Servi, Trends Biotechnol. 1997, 15, 90-96;
3. c) P. D'Arrigo, L. de Ferra, V. Piergianni, A. Ricci, D. Scarcelli, S. Servi, J. Chem. Soc. Chem. Commun. 1994, 1709-1710.
4. a) M. Oblozinsky, R. Ulbrich-Hofmann, L. Bezakova, Biotechnol. Lett. 2005, 27, 181-185;
5. b) S. B. Mandal, P. C. Sen, P. Chakrabarti, Phytochemistry 1980, 19, 1661-1663.
6. a) C. J. Stamler, D. Breznan, T. A.-M. Neville, F. J. Viau, E. Camlioglu, D. L. Sparks, J. Lipid Res. 2000, 41, 1214-1221;
7. b) J. W. Burgess, J. Boucher, T. A.-M. Neville, P. Rouillard, C. Stamler, S. Zachariah, D. L. Sparks, J. Lipid Res. 2003, 44, 1355-1363;
8. c) J. W. Burgess, T. A.-M. Neville, P. Rouillard, Z. Harder, D. S. Beanlands, D. L. Sparks, J. Lipid Res. 2005, 46, 350-355;
9. d) T. Yanagita, Inform 2003, 14, 64-66.
10. J. L. Weihrauch, Y. S. Son, J. Am. Oil Chem. Soc. 1983, 60, 1971-1978.
11. a) I. Leiros, S. McSweeney, E. Hough, J. Mol. Biol. 2004, 339, 805-820;
12. b) I. Leiros, F. Secundo, C. Zambonelli, S. Servi, E. Hough, Structure 2000, 8, 655-667.
13. N. Dittrich, R. Haftendom, R. Ulbrich- Hofmann, Biochim. Biophys. Acta Lipids Lipid Metab. 1998, 1391, 265-272.
14. a) C. Ogino, H. Daido, Y. Ohmura, N. Takada, Y. Itou, A. Kondo, H. Fukuda, N. Shimizu, Biochim. Biophys. Acta Proteins Proteomics 2007, 1774, 671-678;
15. b) Y. Uesugi, J. Arima, M. Iwabuchi, T. Hatanaka, Protein Sci. 2007, 16, 197.-207.
16. C. L. Aikens, A. Laederach, P.J. Reilly, Proteins Struct. Funct. Bioinf. 2004, 57, 27-35.
17. a) Y. Koga, K. Kato, H. Nakano, T. Yamane, J. Mol. Biol. 2003, 331, 585-592;
18. b) R. Kato, H. Nakano, H. Konishi, K. Kato, Y. Koga, T. Yamane, T. Kobayashi, H. Honda, J. Mol. Biol. 2005, 351, 683-692.
19. a) M.T. Reetz, M. Bocola, J.D. Carballeira, D. Zha, A. Vogel, Angew. Chem. 2005, 117, 4264-4268; Angew. Chem. Int. Ed. 2005, 44, 4192-4196;
20. b) M. T. Reetz, J. D. Carballeira, J. Peyralans, H. Höbenreich, A. Maichele, A. Vogel, Chem. Eur. J. 2006, 12, 6031-6038;
21. c) M. T. Reetz, L.-W. Wang, M. Bocola, Angew. Chem. 2006, 118, 1258-1263; Angew. Chem. Int. Ed. 2006, 45, 1236-1241;
22. d) C. M. Clouthier, M. M. Kayser, M. T. Reetz, J. Org. Chem. 2006, 71, 8431-8437.
23. M. S. Warren, S. J. Benkovic, Protein Eng. 1997, 10, 63-68.
24. Y. Iwasaki, S. Horiike, K. Matsushima, T. Yamane, Eur. J. Biochem. 1999, 264, 577-581.
25. M. Konarzycka-Bessler, U. T. Bornscheuer, Angew Chem. 2003, 115, 1449-1451; Angew. Chem. Int. Ed. 2003, 42, 1418-1420.
26. M. A. Lloyd, G. E. Patterson, G. H. Simpson, L. L. Duncan, D. P. King, Y. Fu, B. O. Patrick, S. Parkin, C. P. Brock, Acta Crystallogr. B Struct. Sci. 2007, 63, 433-447.
27. a) D. A. Dougherty, Science 1996, 271, 163-168;
28. b) S. C. R. Lummis, D. L. Beene, N. J. Harrison, H. A. Lester, D. A. Dougherty, Chem. Biol. 2005, 12, 993-997;
29. c) N. Zacharias, D. A. Dougherty, Trends Pharmacol. Sci. 2002, 23, 281-287;
30. d) N. Kunishima, Y. Shimada, Y. Tsuji, T. Sato, M. Yamamoto, T. Kumasaka, S. Nakanishi, H. Jingami, K. Morikawa, Nature 2000, 407, 971-977;
31. e) S. D. Ward, C. A. Curtis, E. C. Hulme, Mol. Pharmacol. 1999, 56, 1031-1041;
32. S. F. Martin, B. C. Follows, P. J. Hergenrother, B. K. Troter, Biochemistry 2000, 39, 3410-3415;
33. g) J. Basran, M. Mewies, F. S. Mathews, N. S. Scrutton, Biochemistry 1997, 36, 1989-1998.
34. a) Y. Iwasaki, N. Mishima, K. Mizumoto, H. Nakano, T. Yamane, J. Ferment. Bioeng. 1995, 79, 417-421;
35. b) N. Mishima, K. Mizumoto, Y. Iwasaki, H. Nakano, T. Yamane, Biotechnol. Prog. 1997, 13, 864-868;
36. c) Y. Iwasaki, H. Nakano, T. Yamane, Appl. Microbiol. Biotechnol. 1994, 42, 290-299;
37. d) Y. Iwasaki, S. Nishikawa, M. Tsuneda, T. Takahasi, T. Yamane, Anal. Biochem. 2004, 329, 157-159.
38. J. C. Dittmer, R. L. Lester, J. Lipid Res. 1964, 5, 126-127.
39. R. Rombaut, J. V. Camp, K. Dewettinck, J. Dairy Sci. 2005, 88, 482-488.
40. a) J. P. Vacca, S. J. deSolms, J. R. Huff, D. C. Billington, R. Baker, J. J. Kulagowski, I. M. Mawer, Tetrahedron 1989, 45, 5679-5702;
41. b) N. Baba, T. Kosugi, H. Daido, H. Umino, Y. Kishicla, S. Nakajima, S. Shimizu, Biosci. Biotechnol. Biochem. 1996, 60, 1916-1918;
42. c) S. J. Angyal, Carbohydr. Res. 2000, 325, 313-320;
43. d) A. M. Riley, C. T. Murphy, C. J. Lindley, J. Westwick, B. V. L. Potter, Bioorg. Med. Chem. Lett. 1996, 6, 2197-2200;
44. e) R. Aneja, S. G. Aneja, Tetrahedron Lett. 2000, 41, 847-850.