Differences in the expression of the ASIP gene are involved in the recessive black coat colour pattern in sheep: Evidence from the rare Xalda sheep breed

Animal Genetics

Volumn 39, Issue 3, 2008, Pages 290-293

  Royo, L J ^a   Alvarez I ^a   Arranz, J J ^b   Fernandez I ^a   Rodriguez A ^a   Perez Pardal L ^a   Goyache, F ^a  

^a Servicio Regional de Investigación y Desarrollo Agroalimentario de Asturias   (Spain)

^b UNIVERSITY OF LEÓN   (Spain)

Author keywords

Agouti; Coat colour; Recessive black; RT PCR; Sheep

Indexed keywords

AGOUTI; ANIMALIA; OVIS; OVIS ARIES;

AGOUTI PROTEIN;

ANIMAL; ARTICLE; DOMINANT GENE; GENE DELETION; GENE EXPRESSION; GENETICS; HAIR COLOR; RECESSIVE GENE; SHEEP;

AGOUTI SIGNALING PROTEIN; ANIMALS; GENE EXPRESSION; GENES, DOMINANT; GENES, RECESSIVE; HAIR COLOR; SEQUENCE DELETION; SHEEP;

EID: 44049099086     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/j.1365-2052.2008.01712.x     Document Type: Article

References (16)

1. Álvarez Sevilla A., Gutiérrez J.P., Fernández I., Royo L.J., Álvarez I., Gómez E. & Goyache F. (2003) Conservación de la oveja Xalda de Asturias. Animal Genetic Resources Information (FAO/UNEP) 34, 41-9.
2. Beraldi D., McRae A.F., Gratten J., Slate J., Visscher P.M. & Pemberton J.M. (2006) Development of a linkage map and mapping of phenotypic polymorphisms in a free-living population of Soay sheep (Ovis aries). Genetics 173, 1521-37.
3. Bultman S.J., Michaud E.J. & Woychik R.P. (1992) Molecular characterization of the mouse agouti locus. Cell 71, 1195-204.
4. Drögemüller C., Giese A., Martins-Wess F., Wiedemann S., Andersson L., Brenig B., Fries R. & Leeb T. (2006) The mutation causing the black-and-tan pigmentation phenotype of Mangalitza pigs maps to the porcine ASIP locus but does not affect its coding sequence. Mammalian Genome 17, 58-66.
5. Fleet M.R. (2006) Development of black-pigmented skin spots and pigmented wool fibres in a Merino flock - causes, field observations and wool measurement. Australian Journal of Agricultural Research 57, 751-60.
6. Goyache F., Gutiérrez J.P., Fernández I., Gómez E., Álvarez I., Diez J. & Royo L.J. (2003) Monitoring pedigree information, to conserve the genetic variability in endangered populations: the Xalda sheep breed, of Asturias as an example. Journal of Animal Breeding and Genetics 120, 95-103.
7. Parsons Y.M., Fleet M.R. & Cooper D.W. (1999a) The Agouti gene: a positional candidate for recessive self-colour pigmentation, in Australian Merino Sheep. Australian Journal of Agricultural Research 50, 1099-103.
8. Parsons Y.M., Fleet M.R. & Cooper D.W. (1999b) Isolation of the ovine agouti coding sequence. Pigment Cell Research 12, 394-7.
9. Rieder S., Taourit S., Mariat D., Langlois B. & Guérin G. (2001) Mutations in the agouti (ASlP), the extension (MC1R) and the brown (TYRP1) loci and their association to coat color phenotypes in horses (Equus caballus). Mammalian Genome 12, 450-5.
10. Royo L.J., Álvarez I., Fernández I., Arranz J.J., Gómez E. & Goyache F. (2005) The coding sequence of the ASIP gene is identical in nine wild-type coloured cattle breeds. Journal of Animal Breeding and Genetics 122, 357-60.
11. Smit M.A., Shay T.L. & Cockett N.B. (2001) A mutation at the agouti locus is associated with recessive black coat color in sheep. Proceedings of the Western Section of the American Society of Animal Science, No. 52, Montana State University, Bozeman.
12. Smit M.A., Shay T.L., Beever J.E., Notter D.R. & Cockett N.E. (2002) Identification of an agouti-like locus in sheep. Animal Genetics 33, 383-5.
13. Sponenberg T.A. (1997) Genetics of colour and hair texture. In: The Genetics of Sheep (Ed. by L. Fries & A. Ruvinsky), pp. 51-86. CAB International, University Press, Cambridge, UK.
14. Våge D.I., Klungland H., Lu D. & Cone R.D. (1999) Molecular and pharmacological characterization of dominant black coat colour in sheep. Mammalian Genome 10, 39-43.
15. Våge D.I., Fleet M.R., Ponz R. et al. (2003) Mapping and characterization of the dominant black colour locus in sheep. Pigment Cell Research 16, 693-7.
16. Voisey J., Gomez-Cabrera M.C., Smit D.J., Leonard J.H., Sturm R.A. & van Daal A. (2006) A polymorphism in the agouti signalling protein (ASIP) is associated with decreased levels of mRNA. Pigment Cell Research 19, 226-31.