Chronic hypoxia-hypercapnia influences cognitive function: A possible new model of cognitive dysfunction in chronic obstructive pulmonary disease

Medical Hypotheses

Volumn 71, Issue 1, 2008, Pages 111-113

  Zheng, Guo qing ^a   Wang, Yan ^a   Wang, Xiao tong ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLOOD VISCOSITY; CHRONIC OBSTRUCTIVE LUNG DISEASE; COGNITIVE DEFECT; HUMAN; HYPERCAPNIA; HYPOXIA; LUNG VASCULAR RESISTANCE; MORTALITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RISK FACTOR;

ANIMALS; ANOXIA; CHRONIC DISEASE; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; HUMANS; HYPERCAPNIA; MEMORY DISORDERS; MODELS, PSYCHOLOGICAL; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

ANIMALIA; RATTUS;

EID: 43949143840     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2008.01.025     Document Type: Article

References (15)

1. Global Initiative for Chronic Obstructive Lung Disease. Pocket guide to COPD diagnosis, management, and prevention. USA: National Institute of Health, National Heart, Lung, and Blood Institute; 2003.
2. Ortapamuk H., and Naldoken S. Brain perfusion abnormalities in chronic obstructive pulmonary disease: comparison with cognitive impairment. Ann Nucl Med 20 2 (2006) 99-106
3. Antonelli-Incalzi R., Corsonello A., Trojano L., Pedone C., Acanfora D., Spada A., et al. Screening of cognitive impairment in chronic obstructive pulmonary disease. Dement Geriatr Cogn Disord 23 4 (2007) 264-270
4. Stump T.E., Callahan C.M., and Hendrie H.C. Cognitive impairment and mortality in older primary care patients. J Am Geriatr Soc 49 7 (2001) 934-940
5. Hida W., Tun Y., Kikuchi Y., Okabe S., and Shirato K. Pulmonary hypertension in patients with chronic obstructive pulmonary disease: recent advances in pathophysiology and management. Respirology 7 1 (2002) 3-13
6. MacNee W. Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part 1. Am J Respir Crit Care Med 150 3 (1994) 833-852
7. Howell K., Ooi H., Preston R., and McLoughlin P. Structural basis of hypoxic pulmonary hypertension: the modifying effect of chronic hypercapnia. Exp Physiol 89 1 (2004) 66-72
8. Grant I., Heaton R.K., McSweeney A.J., Adams K.M., and Timms R.M. Brain dysfunction in COPD. Chest 77 (1980) 308-309
9. American Thoracic Society. Standards for the diagnosis care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 152 (1995) 77-121
10. Incalzi R.A., Gemma A., Marra C., Muzzolon R., Capparella O., and Carbonin P. Chronic obstructive pulmonary disease. An original model of cognitive decline. Am Rev Respir Dis 148 2 (1993) 418-424
11. Antonelli Incalzi R., Marra C., Giordano A., Calcagni M.L., Cappa A., Basso S., et al. Cognitive impairment in chronic obstructive pulmonary disease - a neuropsychological and spect study. J Neurol 250 3 (2003) 325-332
12. Liesker J.J.W., Postma D.S., Beukema R.J., ten Hacken N.H.T., van der Molen T., Riemersma R.A., et al. Cognitive performance in patients with COPD. Respir Med 98 (2004) 351-356
13. Kozora E., Tartar S., and Make B. Brief cognitive screening measures in patients with chronic obstructive pulmonary disease. Arch Clin Neuropsychol 14 8 (1999) 646
14. Schaub R.T., Münzberg H., Borchelt M., Nieczaj R., Hillen T., Reischies F.M., et al. Ventilatory capacity and risk for dementia. J Gerontol A Biol Sci Med Sci 55 11 (2000) M677-M683
15. Chen S.F., Shao S.M., Wu Z.P., Huang H.J., Wang X.T., Gong Y.S., et al. Effect of chronic hypoxia hypercapnia on spatial learning-memory and expression of NMDAR1 in rats. Zhongguo ying yong sheng li xue za zhi 23 4 (2007) 434-437