A general approach to the apparent permeability index

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 35, Issue 2, 2008, Pages 235-248

  Palumbo, Pasquale ^a   Picchini, Umberto ^a,b   Beck, Benoît ^c   Van Gelder, Jan ^d   Delbar, Nathalie ^d   DeGaetano, Andrea ^a  

^a CNR   (Italy)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c Axiosis Sprl ^*  (Belgium)

^d Eli Lilly Benelux   (Belgium)

Author keywords

Caco 2; Drug discovery; Mathematical models; Papp; Permeability index

Indexed keywords

ARTICLE; CELL MEMBRANE; CELL STRAIN CACO 2; COMPARTMENT MODEL; CONFIDENCE INTERVAL; DRUG ABSORPTION; FLOW KINETICS; FLOW RATE; LINEAR SYSTEM; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MEMBRANE PERMEABILITY; OBSERVER BIAS; PERMEABILITY; PRIORITY JOURNAL; SIMULATION;

ALGORITHMS; CACO-2 CELLS; CELL MEMBRANE; HUMANS; INTESTINAL ABSORPTION; LINEAR MODELS; MODELS, STATISTICAL; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS;

EID: 43949112271     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-008-9086-4     Document Type: Article

References (8)

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