Exercise-induced increases in NT-proBNP are not related to the exercise-induced immune response

British Journal of Sports Medicine

Volumn 42, Issue 5, 2008, Pages 383-385

  Scharhag, J ^a   Meyer, T ^a,c   Auracher, M ^a   Muller M ^b   Herrmann, M ^a,b   Gabriel, H ^d   Herrmann, W ^b   Kindermann, W ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF PADERBORN   (Germany)

^d FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BRAIN NATRIURETIC PEPTIDE; C REACTIVE PROTEIN; CARBOHYDRATE; HYDROCORTISONE; INTERLEUKIN 6; PLACEBO;

ADULT; ANAEROBIC THRESHOLD; ARTICLE; ATHLETE; BEVERAGE; BLOOD ANALYSIS; BLOOD SAMPLING; CARBOHYDRATE INTAKE; CELL SUBPOPULATION; CONTROLLED STUDY; CYCLING; ENDURANCE; EXERCISE; FLOW CYTOMETRY; HUMAN; HUMAN EXPERIMENT; IMMUNE RESPONSE; LEUKOCYTE; MALE; MONOCYTE; NATURAL KILLER CELL; NEUTROPHIL; NORMAL HUMAN; SPORTS DRINK; WORKLOAD;

ADULT; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXERCISE; FLOW CYTOMETRY; HUMANS; LEUKOCYTES; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; PHYSICAL ENDURANCE; SPORTS;

EID: 43949102709     PISSN: 03063674     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjsm.2007.039529     Document Type: Article

References (15)

1. Burke MA, Cotts WG. Interpretation of B-type natriuretic peptide in cardiac disease and other comorbid conditions. Heart Fail Rev 2007;12:23-36.
2. Scharhag J, Urhausen A, Schneider G, et al. Reproducibility and clinical significance of exercise-induced increases in cardiac troponins and N-terminal pro brain natriuretic peptide (NT-proBNP) in endurance athletes. Eur J Cardiovasc Prev Rehabil 2006;13:388-97.
3. Steensberg A. The role of IL-6 in exercise-induced immune changes and metabolism. Exerc Immunol Rev 2003;9:40-7.
4. Scharhag J, Meyer T, Gabriel HH, et al. Does prolonged cycling of moderate intensity affect immune cell function? Br J Sports Med 2005;39:171-7.
5. Scharhag J, Meyer T, Gabriel HH, et al. Mobilization and oxidative burst of neutrophils are influenced by carbohydrate supplementation during prolonged cycling in humans. Eur J Appl Physiol 2002;87:584-7.
6. Scharhag J, Meyer T, Auracher M, et al. Effects of graded carbohydrate supplementation on the immune response in cycling. Med Sci Sports Exerc 2006;38:286-92.
7. McLachlan C, Mossop P. Are elevations of N-terminal probrain natriuretic peptide in endurance athletes after prolonged strenuous exercise due to systemic inflammatory cytokines? Am Heart J 2006;152:e1; author reply e3.
8. Ma KK, Ogawa T, de Bold AJ. Selective upregulation of cardiac brain natriuretic peptide at the transcriptional and translational levels by pro-inflammatory cytokines and by conditioned medium derived from mixed lymphocyte reactions via p38 MAP kinase. J Mol Cell Cardiol 2004;36:505-13.
9. Maeder M, Fehr T, Rickli H, et al. Sepsis-associated myocardial dysfunction: diagnostic and prognostic impact of cardiac troponins and natriuretic peptides. Chest 2006;129:1349-66.
10. Rudiger A, Gasser S, Fischler M, et al. Comparable increase of B-type natriuretic peptide and amino-terminal pro-B-type natriuretic peptide levels in patients with severe sepsis, septic shock, and acute heart failure. Crit Care Med 2006;34:2140-4.
11. Hess G, Runkel S, Zdunek D, et al. Reference interval determination for N-terminal-B-type natriuretic peptide (NT-proBNP): A study in blood donors. Clin Chim Acta 2005;360:187-93.
12. Meyer T, Gabriel H, Auracher M, et al. Metabolic profile of 4 h cycling in the field with varying amounts of carbohydrate supply. Eur J Appl Physiol 2003;88:431-7.
13. Gwechenberger M, Hulsmann M, Berger R, et al. Interleukin-6 and B-type natriuretic peptide are independent predictors for worsening of heart failure in patients with progressive congestive heart failure. J Heart Lung Transplant 2004;23:839-44.
14. Tanaka T, Kanda T, Takahashi T, et al. Interleukin-6- induced reciprocal expression of SERCA and natriuretic peptides mRNA in cultured rat ventricular myocytes. J Int Med Res 2004;32:57-61.
15. Wiese S, Breyer T, Dragu A, et al. Gene expression of brain natriuretic peptide in isolated atrial and ventricular human myocardium: influence of angiotensin II and diastolic fiber length. Circulation 2000;102:3074-9.