Quantitative RT-PCR as an alternative to late-stage bioassays for vascular endothelial growth factor

Journal of Pharmaceutical and Biomedical Analysis

Volumn 47, Issue 3, 2008, Pages 460-468

  Burns, Chris J ^a   Silva, Marta M C G ^a   Gray, Elaine ^a   Robinson, C Jane ^a  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

Bioassay; IL 8; Potency assay; Quantitative real time PCR (qRT PCR); Vascular endothelial growth factor (VEGF)

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MONOCLONAL ANTIBODY; THROMBOPLASTIN; VASCULOTROPIN; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR 1;

ARTICLE; BIOASSAY; CELL LINE; CELL LYSATE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG DETERMINATION; DRUG POTENCY; DRUG SCREENING; GENE ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; INCUBATION TIME; INTERMETHOD COMPARISON; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION;

ANTIBODIES, MONOCLONAL; BIOLOGICAL ASSAY; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THROMBOPLASTIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 43949099638     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.02.011     Document Type: Article

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