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Volumn 4, Issue 6, 2008, Pages 571-573
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Bifunctional molecules evade cytochrome P450 metabolism by forming protective complexes with FK506-binding protein
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Author keywords
[No Author keywords available]
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Indexed keywords
BENZOTHIAZOLE DERIVATIVE;
CYTOCHROME P450;
DIAMINE;
FK 506 BINDING PROTEIN;
IMIDAZOLE DERIVATIVE;
LIGAND;
N ((2S,3R) 3 AMINO 2 HYDROXY 4 PHENYLBUTYL) N ISOBUTYL 4 NITROBENZENESULFONAMIDE;
N-((2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYL-4-NITROBENZENESULFONAMIDE;
N1 (2 (4 (DIMETHYLAMINO)PHENYL)BENZOTHIAZOL 5 YL)BUTANE 1,4 DIAMINE;
N1-(2-(4-(DIMETHYLAMINO)PHENYL)BENZOTHIAZOL-5-YL)BUTANE-1,4-DIAMINE;
NITROBENZENE DERIVATIVE;
SULFONAMIDE;
TACROLIMUS;
TAGE COMPOUND;
ANIMAL;
ARTICLE;
BINDING SITE;
BIOLOGICAL MODEL;
CELL MEMBRANE PERMEABILITY;
CELL STRAIN COS1;
CERCOPITHECUS;
CHEMISTRY;
CONFORMATION;
DRUG EFFECT;
HUMAN;
METABOLISM;
PROTEIN BINDING;
STEREOISOMERISM;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
TIME;
ANIMALS;
BENZOTHIAZOLES;
BINDING SITES;
CELL MEMBRANE PERMEABILITY;
CERCOPITHECUS AETHIOPS;
COS CELLS;
CYTOCHROME P-450 ENZYME SYSTEM;
DIAMINES;
HUMANS;
IMIDAZOLES;
LIGANDS;
MODELS, BIOLOGICAL;
MOLECULAR CONFORMATION;
NITROBENZENES;
PROTEIN BINDING;
STEREOISOMERISM;
STRUCTURE-ACTIVITY RELATIONSHIP;
SULFONAMIDES;
TACROLIMUS;
TACROLIMUS BINDING PROTEIN 1A;
TIME FACTORS;
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EID: 43949096905
PISSN: 1742206X
EISSN: 17422051
Source Type: Journal
DOI: 10.1039/b720011k Document Type: Article |
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Times cited : (6)
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References (48)
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