Binding of lipoic acid induces conformational change and appearance of a new binding site in methylglyoxal modified serum albumin

Protein Journal

Volumn 27, Issue 4, 2008, Pages 205-214

  Suji, George ^a   Khedkar, Santosh A ^b   Singh, Sreelekha K ^c   Kishore, Nand ^c   Coutinho, Evans C ^b   Bhor, Vikrant M ^a   Sivakami, S ^a  

^a UNIVERSITY OF MUMBAI   (India)

^b BOMBAY COLLEGE OF PHARMACY   (India)

^c INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

Author keywords

Albumin; Diabetes; Esterase activity; Isothermal titration calorimetry; Lipoic acid; Methylglyoxal; Molecular modelling

Indexed keywords

ESTERASE; HYDROCARBON; IMIDAZOLINE; METHYLGLYOXAL; SERUM ALBUMIN; THIOCTIC ACID; TYROSINE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; ELECTRICITY; ENZYME ACTIVATION; ENZYME INHIBITION; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DOCKING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN STABILITY; SEQUENCE HOMOLOGY;

EID: 43749115757     PISSN: 15723887     EISSN: 18758355     Source Type: Journal    
DOI: 10.1007/s10930-008-9126-3     Document Type: Article

References (32)