Up-regulation of human leukocyte antigen G expression in primary cutaneous malignant melanoma associated with host-vs-tumor immune response

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 28, Issue 2, 2008, Pages 219-221

  Fang, Xianfeng ^a   Zhang, Xuxin ^b   Li, Jiawen ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Three Gorges University   (China)

Author keywords

Cutaneous malignant melanoma; Human leukocyte antigen G

Indexed keywords

HLA ANTIGEN; PROTEIN BCL 2;

ARTICLE; BIOSYNTHESIS; CELL NUCLEUS; CYTOPLASM; GENE EXPRESSION REGULATION; HUMAN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MELANOMA; METABOLISM; MONONUCLEAR CELL; SKIN; SKIN TUMOR; TRANSACTIVATION;

CELL NUCLEUS; CYTOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HLA ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEUKOCYTES, MONONUCLEAR; MELANOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; SKIN; SKIN NEOPLASMS; TRANS-ACTIVATION (GENETICS);

EID: 43749115512     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-008-0227-1     Document Type: Article

References (6)

1. Rouas-Freiss N, Moreau P, Ferrone S et al. HLA-G Proteins in Cancer: Do They Provide Tumor Cells with an Escape Mechanism? Cancer Res 2005,65(22):10139-10144
2. Paul P, Rouas-Freiss N, Khalil-Daher I et al. HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance. Immunol, 1998,59(8):4510-4515
3. Ibrahimel C, Aractingi S, Allory Y et al. Analysis of HLA antigen expression in benign and malignant melanocytic lesions reveals that upregulation of HLA-G expression correlates with malignant transformation, high inflammatory infiltration and HLA-Al genotype. Int J Cancer, 2004,108(2):243-2450
4. van Kempen L C, Ruiter D J, van Muijen G N et al. The tumor microenvironment: a critical determinant of neo-plastic evolution. Eur J Cell Biol, 2003,82(11):539-548
5. LeMaoult J, Le Discorde M, Rouas-Freiss N et al. Biol-ogy and functions of human leukocyte antigen-G in health and sickness. Tissue Antigens, 2003,62(4):273-284
6. Reed J A, Albino A P. Update of diagnostic and prognostic markers in cutaneous malignant melanoma. Clin Lab Med, 2000,20(4):817-838