Antitumoural effect of an L-amino acid oxidase isolated from Bothrops jararaca snake venom

Basic and Clinical Pharmacology and Toxicology

Volumn 102, Issue 6, 2008, Pages 533-542

  De Vieira Santos, Mariana M ^a   Sant'Ana, Carolina D ^b   Giglio, José R ^b   Da Silva, Reinaldo J ^a   Sampaio, Suely V ^b   Soares, Andreimar M ^b   Fecchio, Denise ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID OXIDASE; BATROXOBIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BOTHROPS JARARACA; CANCER INHIBITION; CELL ACTIVATION; CELL STIMULATION; CELL SURVIVAL; DEAMINATION; EHRLICH ASCITES TUMOR; INFLAMMATORY CELL; MACROPHAGE; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SNAKE; SURVIVAL TIME;

AMINO ACIDS; ANIMALS; ANTINEOPLASTIC AGENTS; BOTHROPS; CARCINOMA, EHRLICH TUMOR; CELL MOVEMENT; CROTALID VENOMS; DRUG SCREENING ASSAYS, ANTITUMOR; HYDROGEN PEROXIDE; L-AMINO ACID OXIDASE; MACROPHAGES, PERITONEAL; MALE; MICE; NEUTROPHILS; OXIDATION-REDUCTION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SPECIES SPECIFICITY;

ANIMALIA; BOTHROPS JARARACA;

EID: 43749111771     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2008.00229.x     Document Type: Article

References (45)

1. Markland FS. Snake venoms and the hemostatic system. Toxicon 1998 36 : 1749 800.
2. Braud S, Bom C, Wisner A. Snake venom proteins acting on hemostasis. Biochimie 2000 82 : 851 9.
3. Lewis RJ, Garcia ML. Therapeutic potential of venom peptides. Nat Rev Drug Discov 2003 2 : 790 802.
4. Lu Q, Clemetson JM, Clemetson KJ. Snake venoms and hemostasis. J Thromb Haemost 2005 3 : 1791 9.
5. Duerre JA, Chakrabarty S. L-amino acid oxidases of Proteus rettgeri. J Bacteriol 1975 121 : 656 63.
6. Oudert M. Characterization and physiological function of a soluble L-amino acid oxidase in Corynebacterium. Arch Microbiol 1975 102 : 151 3.
7. Pistorius EK, Voss H. Some properties of a basic L-amino acid oxidase from Anacystis nidulans. Biochim Biophys Acta 1980 611 : 227 40.
8. Niedermann DM, Lerch K. Molecular cloning of the L-amino-acid oxidase gene from Neurospora crassa. J Biol Chem 1990 265 : 17246 51.
9. Vallon O, Bulte L, Kuras R, Olive J, Wollman FA. Extensive accumulation of an extracellular L-amino acid oxidase during gametogenesis of Chlamydomonas reinhardtii. Eur J Biochem 1993 215 : 351 60.
10. Du XY, Clemetson KJ. Snake venom L-amino acid oxidases. Toxicon 2002 40 : 659 65.
11. Suhr SM, Kim DS. Identification of the snake venom substance that induces apoptosis. Biochem Biophys Res Commun 1996 224 : 134 9.
12. Sun LK, Yoshii Y, Hyodo A, Tsurushima H, Saito A, Harakuni T et al. Apoptotic effect in the glioma cells induced by specific protein extracted from Okinawa Habu (Trimeresurus flavoviridis) venom in relation to oxidative stress. Toxicol In Vitro 2003 17 : 169 77.
13. Stábeli RG, Marcussi S, Carlos GB, Pietro RCLR, Selistre-de-Araújo HS, Giglio JR et al. Platelet agreggation and antibacterial effects of an L-amino acid oxidase purified from Bothrops alternatus snake venom. Bioorg Med Chem 2004 12 : 2881 6.
14. Santos MMV, Silva RJ, Silva MG, Fecchio D. Subpopulations of mononuclear leukocytes associated with inhibition of Ehrlich ascites tumor growth by treatment with Bothrops jararaca venom. Mediators Inflamm 2004 13 : 29 32.
15. Rangel-Santos A, Lima A, Lopes-Ferreira M, Cardoso DF. Immunosuprresive role of principal toxin (crotoxin) of Crotalus durissus terrificus venom. Toxicon 2004 44 : 609 16.
16. Toyama MH, Toyama DO, Passero LFD, Laurenti MD, Corbett CE, Tomokane TY et al. Isolation of a new l-amino acid oxidase from Crotalus durissus cascavella venom. Toxicon 2006 47 : 47 57.
17. Izidoro LF, Ribeiro MC, Souza GR, Sant'Ana CD, Hamaguchi A, Homsi-Brandeburgo MI et al. Biochemical and functional characterization of an L-amino acid oxidase isolated from Bothrops pirajai snake venom. Bioorg Med Chem 2006 14 : 7034 43.
18. Stábeli RG, Sant'Ana CD, Ribeiro PH, Costa TR, Ticli FK, Pires MG et al. Cytotoxic L-amino acid oxidase from Bothrops moojeni: biochemical and functional characterization. Int J Biol Macromol 2007 41 : 132 40.
19. França SC, Kashima S, Roberto PG, Marins M, Ticli FK, Pereira JO et al. Molecular approaches for structural characterization of Bothrops L-amino acid oxidases with antiprotozoal activity: cDNA cloning, comparative sequence analysis, and molecular modeling. Biochem Biophys Res Commun 2007 355 : 302 6.
20. Denson KWE, Russel FS, Almagro D, Bishop RC. Characterization of coagulant activity of some snake venoms. Toxicon 1972 10 : 557 62.
21. Gutiérrez JM, Lomonte B. Local tissue damage induced by Bothrops snake venoms. A review. Mem Inst Butantan 1989 51 : 211 23.
22. Barraviera B, Lomonte B, Tarkowski A, Hanson LA, Meira DA. Acute-phase reactions, including cytokynes, in patients bitten by Bothrops and Crotalus snakes in Brazil. J Venom Anim Toxins 1995 1 : 11 22.
23. Goncalves AR, Soares MJ, de Souza W, DaMatta RA, Alves EW. Ultrastructural alterations and growth inhibition of Trypanosoma cruzi and Leishmania major induced by Bothrops jararaca venom. Parasitol Res 2002 88 : 598 602.
24. Silva RJ, Silva MG, Vilela L, Fecchio D. Antitumor effect of Bothrops jararaca venom. Mediators Inflamm 2002a 11 : 99 104.
25. Silva RJ, Silva MG, Vilela L, Fecchio D. Cytokine profile of Ehrlich ascites tumor treated with Bothrops jararaca venom. Mediators Inflamm 2002b 11 : 197 201.
26. Ehrlich P, Apolant H. Beobachtungen uber maligne Mausetumoren. Berl Klin Wschr 1905 28 : 871 4.
27. Rabinovitch M, Destefano MJ. Macrophage spreading in vitro. I. Inducers of spreading. Exp Cell Res 1973 77 : 323 34.
28. Russo M, Teixeira HC, Marcondes MCG, Barbuto A. Superoxide hydrogen peroxide release by activated macrophages. Braz J Med Biol Res 1989 22 : 1271 3.
29. Kaplan EL, Meier P. Nonparametric estimation from incomplete observation. J Am Stat Assoc 1958 53 : 475 81.
30. Miller RG. Survival Analysis. John Wiley & Sons, New York, 1981 238.
31. Tempone AG, Andrade Jr HF, Spencer PJ, Lourenço CO, Rogero JR, Nascimento N. Bothrops moojeni venom kills Leishmania spp. with hydrogen peroxide generated by its L-amino acid oxidase. Biochem Biophys Res Commun 2001 280 : 620 4.
32. Zhang YI, Wang JH, Lee WH, Wang Q, Liu H, Zheng YT et al. Molecular characterization of Trimeresurus stejnegeri venom L-amino acid oxidase with potential anti-HIV activity. Biochem Biophys Res Commun 2003 309 : 598 604.
33. Stiles BG, Sexton FW, Weinstein SA. Antibacterial effects of different snake venoms: purification and characterization of antibacterial proteins from Pseudechis australis (Australian king brown or mulga snake) venom. Toxicon 1991 29 : 1129 41.
34. Iwanaga S, Suzuki T. Enzymes in snake venoms. In : Lee CY (ed.). Snake Venoms. Springer-Verlag, New York, 1979 61 158.
35. Tan NH. L-amino acid oxidases and lactate dehydrogenases. In : Bailey GS (ed.). Enzymes from Snake Venom. Alaken Inc., Fort Collins, CO, 1998 579 98.
36. Souza DHF, Eugenio LM, Fletcher JE, Jiang M, Garrat RC, Oliva G et al. Isolation and structural characterization of a cytotoxic L-amino acid oxidase from Agkistrodon contortrix laticinctus snake venom: preliminary crystaloographic data. Arch Biochem Biophys 1999 368 : 285 90.
37. Torii S, Naito M, Tsuruo T. Apoxin I, a novel apoptosis-inducing factor with L-amino acid oxidase activity purified from Western Diamondback Rattlesnake venom. J Biol Chem 1997 272 : 9539 42.
38. Kanzawa N, Shintani S, Ohta K, Kitajima S, Ehara T, Kobayashi H et al. Achacin induces cell death in HeLa cells through two different mechanisms. Arch Biochem Biophys 2004 422 : 103 9.
39. Iijima R, Kisugi J, Yamazaki M. L-amino acid oxidase activity of an antineoplastic factor of a marine mollusk and its relationship to cytotoxicity. Dev Comp Immunol 2003 27 : 505 12.
40. Takatsuka H, Sakurai Y, Yoshioka A, Kokubo T, Usami Y, Suzuki M et al. Molecular characterization of L-amino acid oxidase from Agkistrodon halys blomhoffii with special reference to platelet aggregation. Biochim Biophys Acta 2001 1544 267 77.
41. Wei JF, Wei Q, Lu QM, Tai H, Jin Y, Wang WY et al. Purification, characterization and biological activity of an L-amino acid oxidase from Trimeresurus mucrosquamatus venom. Acta Biochim Biophys Sin 2002 35 : 219 24.
42. Hale AJ, Smith CA, Sutherland LC, Stoneman VE, Longthorne VL, Culhane LC et al. Apoptosis: molecular regulation of cell death. Eur J Biochem 1996 236 : 1.
43. Ali SA, Stoeva S, Abbasi A, Alam JM, Kayed R, Faigle M et al. Isolation, structural, and functional characterization of an apoptosis inducing L-amino acid oxidase from leaf-nosed viper (Eristocophis macmahoni) snake venom. Arch Biochem Biophys 2000 384 : 216 26.
44. Samel M, Vija H, Rönnholm G, Siigur J, Kalkkinen N, Siigur E. Isolation and characterization of an apoptotic and platelet aggregation inhibiting l-amino acid oxidase from Vipera berus berus (common viper) venom. Biochim Biophys Acta 2006 1764 : 7 14.
45. Farsky SHP, Walber J, Costa Cruz M, Curry Y, Teixeira CFP. Leukocyte response induced by Bothrops jararaca crude venom: in vivo and in vitro studies. Toxicon 1997 35 : 185 93.