Should intensity-modulated radiation therapy be the standard of care in the conservatively managed breast cancer patient?

Journal of Clinical Oncology

Volumn 26, Issue 13, 2008, Pages 2072-2074

  Haffty, Bruce G ^a   Buchholz, Thomas A ^b   McCormick, Beryl ^c  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; CANCER PATIENT; CANCER RADIOTHERAPY; CLINICAL TRIAL; DESQUAMATION; DISEASE FREE SURVIVAL; DOSIMETRY; EDITORIAL; HEAD AND NECK CANCER; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MASTECTOMY; OVERALL SURVIVAL; PARTIAL MASTECTOMY; PRIORITY JOURNAL; PROSTATE CANCER; QUALITY OF LIFE; RADIATION BEAM; RADIATION DOSE; RADIATION FIELD; SKIN TOXICITY; TREATMENT PLANNING; ACUTE DISEASE; ADJUVANT THERAPY; BREAST; BREAST TUMOR; CANCER STAGING; DOSE RESPONSE; FEMALE; HEALTH CARE QUALITY; NOTE; PAIN; PAIN ASSESSMENT; PATHOLOGY; PATIENT SELECTION; RADIATION DERMATITIS; RISK ASSESSMENT; RISK FACTOR; SEGMENTAL MASTECTOMY; STANDARD; TIME; TREATMENT OUTCOME;

ACUTE DISEASE; BREAST; BREAST NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MASTECTOMY, SEGMENTAL; NEOPLASM STAGING; PAIN; PAIN MEASUREMENT; PATIENT SELECTION; QUALITY OF HEALTH CARE; QUALITY OF LIFE; RADIATION DOSAGE; RADIODERMATITIS; RADIOTHERAPY, ADJUVANT; RADIOTHERAPY, INTENSITY-MODULATED; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; TREATMENT OUTCOME;

EID: 43749098063     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2007.15.9442     Document Type: Editorial

References (13)

1. Pignol J: A multicentre randomized trial of breast IMRT to reduce acute radiation dermatitis. J Clin Oncol 26:2085-2092, 2008
2. Eifel P, Axelson JA, Costa J, et al: National Institutes of Health Consensus Development Conference Statement: Adjuvant therapy for breast cancer, November 1-3, 2000. J Natl Cancer Inst 93:979-989, 2001
3. Fisher B, Anderson S, Bryant J, et al: Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 347:1233-1241, 2002
4. Veronesi U, Cascinelli N, Mariani L, et al: Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med 347:1227-1232, 2002
5. Vicini FA, Sharpe M, Kestin L, et al: Optimizing breast cancer treatment efficacy with intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 54:1336-1344, 2002
6. Donovan E, Bleakley N, Denholm E, et al: Randomised trial of standard 2D radiotherapy (RT) versus intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. Radiother Oncol 82:254-264, 2007
7. Whelan T, MacKenzie R, Julian J, et al: Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer. J Natl Cancer Inst 94:1143-1150, 2002
8. Formenti SC, Gidea-Addeo D, Goldberg JD, et al: Phase I-II trial of prone accelerated intensity modulated radiation therapy to the breast to optimally spare normal tissue. J Clin Oncol 25:2236-2242, 2007
9. Arcangeli G, Pinnaro P, Rambone R, et al: A phase III randomized study on the sequencing of radiotherapy and chemotherapy in the conservative management of early-stage breast cancer. Int J Radiat Oncol Biol Phys 64:161-167, 2006
10. Toledano A, Garaud P, Serin D, et al: Concurrent administration of adjuvant chemotherapy and radiotherapy after breast-conservative surgery enhances late toxicities: Long-term results of the ARCOSEIN multicenter randomized study. Int J Radiat Oncol Biol Phys 65:324-332, 2006
11. Eisbruch A: Intensity-modulated radiation therapy in the treatment of head and neck cancer. Nat Clin Pract Oncol 2:34-39, 2005
12. Cahlon O, Hunt M, Zelefsky MJ: Intensity-modulated radiation therapy: Supportive data for prostate cancer. Semin Radiat Oncol 18:48-57, 2008
13. Chui CS, Hong L, Hunt M, et al: A simplified intensity modulated radiation therapy technique for the breast. Med Phys 29:522-529, 2002