The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation

Journal of Biological Chemistry

Volumn 283, Issue 11, 2008, Pages 7176-7184

  Shi, Dashuang ^a,d   Sagar, Vatsala ^b   Jin, Zhongmin ^c   Yu, Xiaolin ^a   Caldovic, Ljubica ^a   Morizono, Hiroki ^a   Allewell, Norma M ^b   Tuchman, Mendel ^c  

^a GEORGE WASHINGTON UNIVERSITY   (United States)

^b Bldg 142   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

^d CHILDREN S RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; ENZYMES; FLOW INTERACTIONS; HYDROGEN; HYDROGEN BONDS; HYDROPHOBICITY; LAWS AND LEGISLATION; MONOMERS; OLIGOMERS; ORGANIC ACIDS; PROTEINS;

ACTIVE SITE RESIDUES; ACTIVE SITES; ARGININE BIOSYNTHETIC PATHWAYS; BOND INTERACTIONS; CATALYTIC FUNCTIONS; CATALYTIC SITES; DO-MAINS; GLUTAMATE SYNTHASE; HEXAMERIC RINGS; HYDROPHOBIC INTERACTIONS; MAIN CHAINS; MODE OF BINDINGS; NEISSERIA GONORRHOEAE; NITROGEN ATOMS; POINT SYMMETRIES; RING DIAMETERS; SIDE CHAINS; SYMMETRY AXES; SYNTHASE;

CRYSTAL STRUCTURE;

ACETYL COENZYME A; ACYLTRANSFERASE; ARGININE; BACTERIAL ENZYME; COENZYME A; CYSTEINE; DIMER; GLUTAMATE ACETYLTRANSFERASE; LEUCINE; MONOMER; N ACETYLGLUTAMIC ACID; NITROGEN; PHOSPHOTRANSFERASE; SERINE; AMINO ACID ACETYLTRANSFERASE;

ARTICLE; BINDING SITE; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HYDROGEN BOND; NEISSERIA GONORRHOEAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; RING CHROMOSOME; STRUCTURE ANALYSIS; BIOLOGICAL MODEL; CHEMISTRY; CONFORMATION; ENZYMOLOGY; PROTEIN TERTIARY STRUCTURE; STEREOISOMERISM; X RAY CRYSTALLOGRAPHY;

NEISSERIA GONORRHOEAE;

ACETYLTRANSFERASES; ALLOSTERIC SITE; AMINO-ACID N-ACETYLTRANSFERASE; ARGININE; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; LEUCINE; MODELS, BIOLOGICAL; MOLECULAR CONFORMATION; NEISSERIA GONORRHOEAE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SERINE; STEREOISOMERISM;

EID: 43749094344     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707678200     Document Type: Article

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