One-pot synthesis of β-imidazolylpropionamides

Tetrahedron Letters

Volumn 49, Issue 25, 2008, Pages 3997-4002

  Ryabukhin, Sergey V ^a,b   Granat, Dmitry S ^a   Khodakovskiy, Pavel V ^a,b   Shivanyuk, Alexander N ^a,b   Tolmachev, Andrey A ^b  

^a ENAMINE LTD   (Ukraine)

^b TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

Author keywords

Imidazolylpropionamides; Acrylic acids; Acylation; Carbonyldiimidazole (CDI)

Indexed keywords

BETA IMIDAZOLYLPROPIONAMIDE DERIVATIVE; CARBONYLDIIMIDAZOLE; IMIDAZOLE; PROPIONAMIDE DERIVATIVE;

ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 43649105119     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2008.04.096     Document Type: Article

References (11)

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9. 3 (8 mL). Targeted products 4a-d, 4g, 4i-m, 4o-r were formed after the evaporation of DCM.
10. β-Imidazolylpropionamide 4s was synthesized by general procedure and isolated by preparative chromatography.
11. 13C NMR (125 MHz) were recorded on a Bruker Avance DRX 500 spectrometer with TMS as an internal standard.