Gender Differences in Mortality After Mitral Valve Operation: Evidence for Higher Mortality in Perimenopausal Women

Annals of Thoracic Surgery

Volumn 85, Issue 6, 2008, Pages 2040-2045

  Song, Howard K ^a   Grab, Joshua D ^b   O'Brien, Sean M ^b   Welke, Karl F ^a   Edwards, Fred ^c   Ungerleider, Ross M ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AGING; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MITRAL VALVE REPAIR; MITRAL VALVE REPLACEMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; SURGICAL MORTALITY; SURVIVAL;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CAUSE OF DEATH; COMORBIDITY; FEMALE; FOLLOW-UP STUDIES; HEART VALVE DISEASES; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; MITRAL VALVE; PERIMENOPAUSE; POSTOPERATIVE COMPLICATIONS; RISK ADJUSTMENT; SEX RATIO;

EID: 43649099436     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2008.02.082     Document Type: Article

References (38)

1. Richardson J.V., and Cyrus R.J. Reduced efficacy of coronary artery bypass grafting in women. Ann Thorac Surg 42 (1986) S16-S21
2. Hannan E.L., Bernard H.R., Kilburn Jr. H.C., and O'Donnell J.F. Gender differences in mortality rates for coronary artery bypass surgery. Am Heart J 123 (1992) 866-872
3. O'Connor G.T., Morton J.R., Diehl M.J., et al. Differences between men and women in hospital mortality associated with coronary artery bypass graft surgery. The Northern New England Cardiovascular Disease Study Group. Circulation 88 (1993) 2104-2110
4. Carey J.S., Cukingnan R.A., and Singer L.K. Health status after myocardial revascularization: inferior results in women. [see comment]. Ann Thorac Surg 59 (1995) 112-117
5. Jaglal S.B., Tu J.V., and Naylor C.D. Higher in-hospital mortality in female patients following coronary artery bypass surgery: a population-based study. Provincial Adult Cardiac Care Network of Ontario. Clin Invest Med 18 (1995) 99-107
6. Utley J.R., Wilde E.F., Leyland S.A., Morgan M.S., and Johnson H.D. Intraoperative blood transfusion is a major risk factor for coronary artery bypass grafting in women. [see comment]. Ann Thorac Surg 60 (1995) 570-574 4-5
7. Farrer M., Skinner J.S., Albers C.J., Alberti K.G., and Adams P.C. Outcome after coronary artery surgery in women and men in the north of England. QJM 90 (1997) 203-211
8. Hammar N., Sandberg E., Larsen F.F., and Ivert T. Comparison of early and late mortality in men and women after isolated coronary artery bypass graft surgery in Stockholm, Sweden, 1980 to 1989. J Am Coll Cardiol 29 (1997) 659-664
9. Simchen E., Israeli A., Merin G., and Ferderber N. Israeli women were at a higher risk than men for mortality following coronary bypass surgery. Eur J Epidemiol 13 (1997) 503-509
10. Edwards F.H., Carey J.S., Grover F.L., Bero J.W., and Hartz R.S. Impact of gender on coronary bypass operative mortality. [see comment]. Ann Thorac Surg 66 (1998) 125-131
11. Herlitz J., Brandrup-Wognsen G., Karlson B.W., et al. Mortality, risk indicators for death, and mode of death in younger and elderly patients during five years after coronary artery bypass graft. Clin Cardiol 23 (2000) 421-426
12. Christakis G.T., Weisel R.D., Buth K.J., et al. Is body size the cause for poor outcomes of coronary artery bypass operations in women?. J Thorac Cardiovasc Surg 110 (1995) 1344-1356 discussion 1356-8
13. Brandrup-Wognsen G., Berggren H., Hartford M., Hjalmarson A., Karlsson T., and Herlitz J. Female sex is associated with increased mortality and morbidity early, but not late, after coronary artery bypass grafting. [see comment]. Eur Heart J 17 (1996) 1426-1431
14. Delyani J.A., Murohara T., Nossuli T.O., and Lefer A.M. Protection from myocardial reperfusion injury by acute administration of 17 beta-estradiol. J Mol Cell Cardiol 28 (1996) 1001-1008
15. Hale S.L., Birnbaum Y., and Kloner R.A. beta-Estradiol, but not alpha-estradiol, reduced myocardial necrosis in rabbits after ischemia and reperfusion. Am Heart J 132 (1996) 258-262
16. Kim Y.D., Chen B., Beauregard J., et al. 17 beta-Estradiol prevents dysfunction of canine coronary endothelium and myocardium and reperfusion arrhythmias after brief ischemia/reperfusion. Circulation 94 (1996) 2901-2908
17. Wichmann M.W., Zellweger R., DeMaso C.M., Ayala A., and Chaudry I.H. Enhanced immune responses in females, as opposed to decreased responses in males following haemorrhagic shock and resuscitation. Cytokine 8 (1996) 853-863
18. Kolodgie F.D., Farb A., Litovsky S.H., et al. Myocardial protection of contractile function after global ischemia by physiologic estrogen replacement in the ovariectomized rat. J Mol Cell Cardiol 29 (1997) 2403-2414
19. Node K., Kitakaze M., Kosaka H., Minamino T., Funaya H., and Hori M. Amelioration of ischemia- and reperfusion-induced myocardial injury by 17beta-estradiol: role of nitric oxide and calcium-activated potassium channels. Circulation 96 (1997) 1953-1963
20. Zellweger R., Wichmann M.W., Ayala A., Stein S., DeMaso C.M., and Chaudry I.H. Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males. Crit Care Med 25 (1997) 106-110
21. Angele M.K., Knoferl M.W., Schwacha M.G., et al. Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage. Am J Physiol 277 (1999) C35-C42
22. Booth E.A., Marchesi M., Kilbourne E.J., and Lucchesi B.R. 17Beta-estradiol as a receptor-mediated cardioprotective agent. J Pharmacol Exp Ther 307 (2003) 395-401
23. Horton J.W., White D.J., and Maass D.L. Gender-related differences in myocardial inflammatory and contractile responses to major burn trauma. Am J Physiol Heart Circ Physiol 286 (2004) H202-H213
24. Kher A., Wang M., Tsai B.M., et al. Sex differences in the myocardial inflammatory response to acute injury. Shock 23 (2005) 1-10
25. Zhai P., Eurell T.E., Cotthaus R., Jeffery E.H., Bahr J.M., and Gross D.R. Effect of estrogen on global myocardial ischemia-reperfusion injury in female rats. Am J Physiol Heart Circ Physiol 279 (2000) H2766-H2775
26. Beer S., Reincke M., Kral M., et al. Susceptibility to cardiac ischemia/reperfusion injury is modulated by chronic estrogen status. J Cardiovasc Pharmacol 40 (2002) 420-428
27. Deshpande R., Khalili H., Pergolizzi R.G., Michael S.D., and Chang M.D. Estradiol down-regulates LPS-induced cytokine production and NFkB activation in murine macrophages. Am J Reprod Immunol 38 (1997) 46-54
28. Schroder J., Kahlke V., Staubach K.H., Zabel P., and Stuber F. Gender differences in human sepsis. [see comment]. Arch Surg 133 (1998) 1200-1205
29. Mizushima Y., Wang P., Jarrar D., Cioffi W.G., Bland K.I., and Chaudry I.H. Estradiol administration after trauma-hemorrhage improves cardiovascular and hepatocellular functions in male animals. Ann Surg 232 (2000) 673-679
30. Alvarez R.J., Gips S.J., Moldovan N., et al. 17beta-estradiol inhibits apoptosis of endothelial cells. Biochem Biophys Res Commun 237 (1997) 372-381
31. Roggia C., Gao Y., Cenci S., et al. Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proc Nat Acad Sci U S A 98 (2001) 13960-13965
32. Monroe D.G., Berger R.R., and Sanders M.M. Tissue-protective effects of estrogen involve regulation of caspase gene expression. Mol Endocrinol 16 (2002) 1322-1331
33. Seck T., Diel I., Bismar H., Ziegler R., and Pfeilschifter J. Expression of Interleukin-6 (IL-6) and IL-6 receptor mRNA in human bone samples from pre- and postmenopausal women. Bone 30 (2002) 217-222
34. Dantas A.P.V., Franco M.d.C.P., Tostes R.C.A., et al. Relative contribution of estrogen withdrawal and gonadotropins increase secondary to ovariectomy on prostaglandin generation in mesenteric microvessels. J Cardiovasc Pharmacol 43 (2004) 48-55
35. Edwards F.H., Peterson E.D., Coombs L.P., et al. Prediction of operative mortality after valve replacement surgery. J Am Coll Cardiol 37 (2001) 885-892
36. Enriquez-Sarano M., Schaff H.V., Orszulak T.A., Tajik A.J., Bailey K.R., and Frye R.L. Valve repair improves the outcome of surgery for mitral regurgitation. A multivariate analysis. [see comment]. Circulation 91 (1995) 1022-1028
37. Suri R.M., Schaff H.V., Dearani J.A., et al. Survival advantage and improved durability of mitral repair for leaflet prolapse subsets in the current era. [see comment]. Ann Thorac Surg 82 (2006) 819-826
38. Lobo R.A. Menopause: endocrinology, consequences of estrogen deficiency, effects of hormone replacement therapy, treatment regimens. In: Katz V.L., Lentz G.M., Lobo R.A., and Gershenson D.M. (Eds). Comprehensive gynecology. 5th ed. (2007), Mosby-Elsevier, Philadelphia, PA 1039-1065