Higher detection rate of JAK2 mutation using plasma

Blood

Volumn 111, Issue 7, 2008, Pages 3906-3907

  Wanlong, Ma ^a   Kantarjian, Hagop ^a   Zhang, Xi ^a   Sun, Weimin ^a   Buller, Arlene M ^a   Jilani, Iman ^a   G Schwartz, Joyce ^a   Giles, Francis ^a   Albitar, Maher ^a  

^a QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE 2; JAK2 PROTEIN, HUMAN; MESSENGER RNA; RNA;

BLOOD CELL; CONTROLLED STUDY; ERYTHROCYTOSIS; GENE MUTATION; HEMIZYGOTE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; LETTER; MYELOID LEUKEMIA; MYELOPROLIFERATIVE DISORDER; PLASMA; POLYCYTHEMIA VERA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; WILD TYPE; BLOOD; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; SENSITIVITY AND SPECIFICITY;

DNA MUTATIONAL ANALYSIS; HUMANS; JANUS KINASE 2; LEUKEMIA, MYELOID; MYELOPROLIFERATIVE DISORDERS; PLASMA; POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; SENSITIVITY AND SPECIFICITY;

EID: 43549088370     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-02-139188     Document Type: Letter

References (7)

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2. Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet. 2005;365:1054-1061. Erratum in Lancet. 2005;366:122.
3. James C. Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144-1148.
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7. Ma W, Kantarjian H, Jilani l et al. Heterogeneity in detecting Abl kinase mutations and better sensitivity using circulating plasma RNA. Leukemia. 2006;20:1989-1991.