Symptomatic Pulmonary Hypertension in a Child with Sickle Cell Disease

Journal of Pediatrics

Volumn 152, Issue 6, 2008, Pages 879-881

  Villavicencio, Karrie ^a   Ivy, Dunbar ^a   Cole, Laura ^b   Nuss, Rachelle ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIURETIC AGENT; SILDENAFIL; STEROID;

ANAMNESIS; ARTICLE; CASE REPORT; CLINICAL FEATURE; DISEASE COURSE; DRUG DOSE INCREASE; ECHOCARDIOGRAPHY; ERYTHROCYTE TRANSFUSION; HEART CATHETERIZATION; HEART LEFT VENTRICLE HYPERTROPHY; HEMOLYSIS; HUMAN; MALE; NEWBORN SCREENING; PRIORITY JOURNAL; PULMONARY HYPERTENSION; PULSE OXIMETRY; SCHOOL CHILD; SICKLE CELL ANEMIA; THORAX RADIOGRAPHY; TREATMENT DURATION; TRICUSPID VALVE REGURGITATION;

ANEMIA, SICKLE CELL; CHILD; HUMANS; HYPERTENSION, PULMONARY; MALE;

EID: 43549085270     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2008.01.042     Document Type: Article

References (10)

1. Wang X., Tanus-Santos J.E., Reiter C.D., Dejam A., Shiva S., Smith R.D., et al. Biologic activity of nitric oxide in the plasmatic compartment. Proc Natl Acad Sci U S A 101 (2004) 11477-11482
2. Gladwin M.T., Sachdev V., Jison M.L., Shizukada Y., Plehn J.F., Minter K., et al. Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med 350 (2004) 886-895
3. Machado R.F., Anthi A., Steinberg M.H., Bonds D., Sachdev V., Kato G.J., et al. N-terminal pro-brain natriuretic protein levels and risk of death in sickle cell disease. JAMA 296 (2006) 310-318
4. Sachdev V., Machado R.F., Shizukuda Y., Rao Y.N., Sidenko S., Ernst I., et al. Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease. J Am Coll Cardiol 49 (2007) 472-479
5. Hagar R.W., Michlitsch J.G., Gardner J., Vichinsky E.P., and Morris C.R. Clinical differences between children and adults with pulmonary hypertension and sickle cell disease. Br J Haematol 140 (2008) 104-112
6. Machado R.F., and Gladwin M.T. Chronic sickle cell lung disease: new insights into the diagnosis, pathogenesis and treatment of pulmonary hypertension. Br J Haematol 129 (2005) 449-464
7. Kato G.J., McGowan V., Machado R.F., Little J.A., Taylor J., Morris C.R., et al. Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease. Blood 107 (2006) 2279-2285
8. Castro O., and Gladwin M.T. Pulmonary hypertensionin sickle cell disease: mechanisms, diagnosis, and management. Hematol Oncol Clin North Am 19 (2005) 881-896
9. Morris C.R., Morris Jr. S.M., Hagar W., van Warmerdam J., Claster S., Keptka-Lenhart D., et al. Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?. Am J Respir Crit Care Med 168 (2003) 63-69
10. Machado R.F., Martyr S., Kato G.J., Barst R.J., Anthi A., Robinson M.R., et al. Sildenafil therapy in patients with sickle cell disease and pulmonary hypertension. Br J Haematol 130 (2005) 445-453