A novel gene, ecl1+, extends the chronological lifespan in fission yeast

FEMS Yeast Research

Volumn 8, Issue 4, 2008, Pages 520-530

  Ohtsuka, Hokuto ^a   Mita, Satoka ^a   Ogawa, Yuki ^a   Azuma, Kenko ^a   Ito, Hirokazu ^a   Aiba, Hirofumi ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Aging; Chronological lifespan; Fission yeast

Indexed keywords

FUNGAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; PROTEIN DELTA PKA1; PROTEIN DELTA SCK2; PROTEIN ECL1; PROTEIN STE11;

ARTICLE; CELL AGING; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; FUNGAL STRAIN; GROWTH CURVE; LIFESPAN; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN EXPRESSION; SCHIZOSACCHAROMYCES POMBE;

AMINO ACID SEQUENCE; BASE SEQUENCE; BLOTTING, NORTHERN; CELL NUCLEUS; FUNGAL PROTEINS; GENE DELETION; GENE DOSAGE; GENE EXPRESSION PROFILING; MICROBIAL VIABILITY; MOLECULAR SEQUENCE DATA; PLASMIDS; SCHIZOSACCHAROMYCES;

SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

EID: 43549084417     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1111/j.1567-1364.2008.00379.x     Document Type: Article

References (24)

1. + gene is a target of the signaling pathway involving Wis1 MAP-kinase kinase in fission yeast. FEBS Lett 376 : 199 201.
2. Aiba H, Kawaura R, Yamamoto E, Yamada H, Takegawa K Mizuno T (1998) Isolation and characterization of high-osmolarity-sensitive mutants of fission yeast. J Bacteriol 180 : 5038 5043.
3. +, the function of which is necessary for growth under high osmotic stress in fission yeast. Biosci Biotechnol Biochem 64 : 1099 1102.
4. Craven RA, Griffiths DJ, Sheldrick KS, Randall RE, Hagan IM Carr AM (1998) Vectors for the expression of tagged proteins in Schizosaccharomyces pombe. Gene 221 : 59 68.
5. Fabrizio P Longo VD (2003) The chronological life span of Saccharomyces cerevisiae. Aging Cell 2 : 73 81.
6. Fabrizio P, Pozza F, Pletcher SD, Gendron CM Longo VD (2001) Regulation of longevity and stress resistance by Sch9 in yeast. Science 292 : 288 290.
7. Fabrizio P, Liou LL, Moy VN, Diaspro A, SelverstoneValentine J, Gralla EB Longo VD (2003) SOD2 functions downstream of Sch9 to extend longevity in yeast. Genetics 163 : 35 46.
8. +, which affects viability after entry into the stationary phase in Schizosaccharomyces pombe. Biosci Biotechnol Biochem 71 : 3041 3047.
9. Guarente L Picard F (2005) Calorie restriction - the SIR2 connection. Cell 120 : 473 482.
10. Higuchi T, Watanabe Y Yamamoto M (2002) Protein kinase A regulates sexual development and gluconeogenesis through phosphorylation of the Zn finger transcriptional activator Rst2p in fission yeast. Mol Cell Biol 22 : 1 11.
11. Krawchuk MD Wahls WP (1999) High-efficiency gene targeting in Schizosaccharomyces pombe using a modular, PCR-based approach with long tracts of flanking homology. Yeast 15 : 1419 1427.
12. Liu X, McLeod I, Anderson S, Yates JR III. He X (2005) Molecular analysis of kinetochore architecture in fission yeast. EMBO J 24 : 2919 2930.
13. Longo VD Fabrizio P (2002) Regulation of longevity and stress resistance: a molecular strategy conserved from yeast to humans? Cell Mol Life Sci 59 : 903 908.
14. Longo VD Kennedy BK (2006) Sirtuins in aging and age-related disease. Cell 126 : 257 268.
15. Maundrell K (1993) Thiamine-repressible expression vectors pREP and pRIP for fission yeast. Gene 123 : 127 130.
16. Moreno S, Klar A Nurse P (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 194 : 795 823.
17. +, the function of which is necessary for growth under high osmotic stress in fission yeast. Biosci Biotechnol Biochem 64 : 2493 2496.
18. North BJ Sinclair DA (2007) Sirtuins: a conserved key unlocking AceCS activity. Trends Biochem Sci 32 : 1 4.
19. +, results in a decrease in viability after entry into the stationary phase in fission yeast. Mol Genet Genom 269 : 437 442.
20. Piper PW (2006) Long-lived yeast as a model for ageing research. Yeast 23 : 215 226.
21. Roux AE, Quissac A, Chartrand P, Ferbeyre G Rokeach LA (2006) Regulation of chronological aging in Schizosaccharomyces pombe by the protein kinases Pka1 and Sck2. Aging Cell 5 : 345 357.
22. Sanchez-Perez I, Renwick SJ, Crawley K, Karig I, Buck V, Meadows JC, Franco-Sanchez A, Fleig U, Toda T Millar JB (2005) The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast. EMBO J 24 : 2931 2943.
23. Wilkinson MG Millar JB (1998) SAPKs and transcription factors do the nucleocytoplasmic tango. Genes Dev 12 : 1391 1397.
24. Yamada H, Ohmiya R, Yamamoto E, Aiba H Mizuno T (1997) Characterization of multicopy suppressor genes that complement a defect in the Wis1-Sty1 MAP kinase cascade involved in stress responses in Schizosaccharomyces pombe. J Gen Appl Microbiol 43 : 209 215.