Construction of self-cloning industrial brewing yeast with high-glutathione and low-diacetyl production

International Journal of Food Science and Technology

Volumn 43, Issue 6, 2008, Pages 989-994

  Wang, Zhao Yue ^a   He, Xiu Ping ^a   Liu, Nan ^a   Zhang, Bo Run ^a  

^a INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

Diacetyl; Glutathione; Industrial brewing yeast; Self cloning strains

Indexed keywords

SACCHAROMYCES CEREVISIAE;

EID: 43449133559     PISSN: 09505423     EISSN: 13652621     Source Type: Journal    
DOI: 10.1111/j.1365-2621.2007.01546.x     Document Type: Article

References (23)

1. Akada, R. (2002). Genetically modified industrial yeast ready for application. Journal of Bioscience and Bioengineering, 94, 563–544.
2. Blomqvist, K., Suihko, M.L., Knowles, J. & Penttila, M. (1991). Chromosomal integration and expression of two bacterial α‐acetolactate decarboxylase genes in brewer’s yeast. Applied and Environmental Microbiology, 57, 2796–2803.
3. Bradford, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein‐dye binding. Analytical Biochemistry, 72, 248–254.
4. Burke, D., Dawson, D. & Stearns, T. (2000). Yeast DNA isolations. In: Methods in Yeast Genetics. A cold spring harbor laboratory course manual. Pp. 109–111.
5. Douglas, K.T. (1987). Mechanisms of action of glutathione‐dependent enzymes. In: Advances in Enzymology. Meister, A. (ed.) Pp. 103–167. New York: John Wiley & Sons.
6. Fan, X., He, X., Guo, X., Qu, N., Wang, C. & Zhang, B. (2004). Increasing glutathione formation by functional expression of the γ‐glutamylcysteine synthetase gene in Saccharomyces cerevisiae. Biotechnology Letters, 26, 415–417.
7. Gjermansen, C., Nilsson‐Tillgren, T., Petersen, J.G., Kielland‐Brandt, M.C., Sigsgaard, P. & Holmberg, S. (1988). Towards diacetyl‐less brewers’ yeast. Influence of ILV 2 and ILV 5 mutations. Journal of Basic Microbiology, 28, 175–183.
8. He, X., Huai, W., Tie, C., Liu, Y. & Zhang, B. (2000). Breeding of high ergosterol‐producing yeast strains. Journal of Industrial Microbiology and Biotechnology, 25, 39–44.
9. Li, Q., Pan, X.Q. & Gu, G.X. (2004). Improvement of beer flavor stability by screening anti‐staling brewers’ yeast. Chinese Journal of Biotechnology, 20, 912–917.
10. Li, Y., Tie, C.J., Wang, Z.X., Zhang, B.R. & Zhu, G.J. (2002). Construction of diacetyl‐low brewer’s yeast. Liquor Making, 29, 77–79. In Chinese.
11. Magee, P.T. & Robichon‐Szulmajster, D.H. (1968). The regulation of isoleucine–valine biosynthesis in Saccharomyces cerevisiae. 2. Identification and characterization of mutants lacking acteohydroxyacid synthase. European Journal of Biochemistry, 3, 502–506.
12. Mithieux, S.M. & Weiss, A.S. (1995). Integration of multiple ILV5 copies and elevated transcription in polyploid yeast. Yeast, 11, 311–316.
13. Ohtake, Y., Watanabe, K., Tezuka, H., et al. (1989). Expression of the glutathione synthetase gene of Escherichia coli B in Saccharomyces cerevisiae. Journal of Fermentation and Bioengineering, 68, 390–394.
14. Orna, C.H. & Gisela, S. (2000). Roles of the glutathione‐and thioredoxin‐dependent reduction systems in the Escherichia coli and Saccharomyces cerevisiae responses to oxidative stress. Annual Review of Microbiology, 54, 439–461.
15. Pang, S.S. & Duggleby, R.G. (2001). Regulation of yeast acetohydroxyacid synthase by valine and ATP. Biochemical Journal, 357, 749–757.
16. Sambrook, J., Fritsch, E.F. & Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, 2nd edn. New York: Cold Spring Harbor Laboratory Press.
17. Schiestl, R.H. & Gietz, R.D. (1989). High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Current Genetics, 16, 339–46.
18. Sone, H., Fujii, T., Kondo, K., Shimizu, F., Tanaka, J. & Inoue, T. (1988). Nucleotide sequence and expression of the Enterobacter aerogenes alpha‐acetolactate decarboxylase gene in brewer’s yeast. Applied and Environmental Microbiology, 54, 38–42.
19. Villa, K.D., Lee, S., Masschelein, C.A., Goossens, E., Debourg, A. & Masschelein, C.A. (1995). Control of vicinal diketone production by brewer’s yeast. I. Effects of ILV5 and ILV3 gene amplification on vicinal diketone production and ILV enzyme activity. Journal of the American Society of Brewing Chemists, 53, 49–53.
20. Villanueba, K.D., Goossens, E. & Masschelein, C.A. (1990). Subthreshold vicinal diketone levels in Lager brewing yeast fermentations by means of ILV5 gene amplification. Journal of the American Society of Brewing Chemists, 48, 111–114.
21. Wang, Y.N. & Xiao, D.G (2002). A rapid determination of method of alcohol and real fermentation degree in beer. Liquor Making, 29, 84–86. (in Chinese)
22. Yamano, S., Tanaka, J. & Inoue, T. (1994). Cloning and expression of the gene encoding α‐acetolactate decarboxylase from Acetobacter aceti ssp. xylinum in brewer’s yeast. Journal of Biotechnology, 32, 165–171.
23. Yasuyuki, O. & Seizou, Y. (1991). Molecular cloning of the γ‐glutamylcysteine synthetase gene (GSH‐I) of Saccharomyces cerevisiae. Yeast, 7, 953–961.