Simultaneous genotyping of coagulation factor XI type II and type III mutations by multiplex real-time polymerase chain reaction to determine their prevalence in healthy and factor XI-deficient Italians

Haematologica

Volumn 93, Issue 5, 2008, Pages 715-721

  Zadra, Giorgia ^a   Asselta, Rosanna ^a   Tenchini, Maria Luisa ^a   Castaman, Giancarlo ^b   Seligsohn, Uri ^c   Mannucci, Pier Mannuccio ^a   Duga, Stefano ^a,d  

^a UNIVERSITY OF MILAN   (Italy)

^b SAN BORTOLO HOSPITAL   (Italy)

^c TEL AVIV UNIVERSITY   (Israel)

^d IRCCS Maggiore Hospital ^*  (Italy)

Author keywords

Factor XI deficiency; Jewish founder effect; Multiplex real time PCR; Type II and type III mutations

Indexed keywords

BLOOD CLOTTING FACTOR 11;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; BLOOD CLOTTING FACTOR 11 DEFICIENCY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE SEVERITY; DNA SEQUENCE; FEMALE; GENE MUTATION; GENETIC ANALYSIS; GENOTYPE; HAPLOTYPE; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; PREVALENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; ADULT; AGED; FACTOR XI; FACTOR XI DEFICIENCY; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; ITALY; MALE; MIDDLE AGED; MUTATION; PREVALENCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 43449124745     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: 10.3324/haematol.12180     Document Type: Article

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