Regions downstream from the WW domain of dystrophin are important for binding to postsynaptic densities in the brain

Neuromuscular Disorders

Volumn 18, Issue 5, 2008, Pages 382-388

  Sakamoto, Tetsuro ^a   Arima, Toshiyuki ^a   Ishizaki, Masatoshi ^a   Kawano, Ryoko ^a   Koide, Tatsuya ^a   Uchida, Yuji ^a   Yamashita, Satoshi ^a   Kimura, En ^a   Hirano, Teruyuki ^a   Maeda, Yasushi ^a   Uchino, Makoto ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Adenovirus vector; Hippocampus; mdx mouse; Minidystrophin; Neuron; Primary culture

Indexed keywords

ADENOVIRUS VECTOR; COMPLEMENTARY DNA; CYSTEINE; DYSTROPHIN; POSTSYNAPTIC DENSITY PROTEIN 95;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOPLASM; EMBRYO; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MOUSE; NERVE FIBER; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ADENOVIRIDAE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BLOTTING, WESTERN; BRAIN; CELL CULTURE TECHNIQUES; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; DYSTROPHIN; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC VECTORS; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; SYNAPSES; TRANSFECTION;

EID: 43449122729     PISSN: 09608966     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nmd.2008.02.004     Document Type: Article

References (44)

1. Koenig M., Hoffman E.P., Bertelson C.J., et al. Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals. Cell 50 (1987) 509-517
2. Hoffman E.P., Brown Jr. R.H., and Kunkel L.M. Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 51 (1987) 919-928
3. Koenig M., Monaco A.P., and Kunkel L.M. The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein. Cell 53 (1988) 219-228
4. Nicholson L.V., Johnson M.A., Bushby K.M., et al. Integrated study of 100 patients with Xp21 linked muscular dystrophy using clinical, genetic, immunochemical, and histopathological data. Part 2. Correlations within individual patients. J Med Genet 30 (1993) 737-744
5. Billard C., Gillet P., Signoret J.L., et al. Cognitive functions in Duchenne muscular dystrophy: a reappraisal and comparison with spinal muscular atrophy. Neuromuscul Disord 2 (1992) 371-378
6. Muntoni F., Mateddu A., and Serra G. Passive avoidance behaviour deficit in the mdx mouse. Neuromuscul Disord 1 (1991) 121-123
7. Sesay A.K., Errington M.L., Levita L., et al. Spatial learning and hippocampal long-term potentiation are not impaired in mdx mice. Neurosci Lett 211 (1996) 207-210
8. Suzuki A., Yoshida M., Yamamoto H., et al. Glycoprotein-binding site of dystrophin is confined to the cysteine-rich domain and the first half of the carboxy-terminal domain. FEBS Lett 308 (1992) 154-160
9. Einbond A., and Sudol M. Towards prediction of cognate complexes between the WW domain and proline-rich ligands. FEBS Lett 384 (1996) 1-8
10. Lidov H.G., Byers T.J., Watkins S.C., et al. Localization of dystrophin to postsynaptic regions of central nervous system cortical neurons. Nature 348 (1990) 725-728
11. Uchino M., Yoshioka K., Miike T., et al. Dystrophin and dystrophin-related protein in the brains of normal and mdx mice. Muscle Nerve 17 (1994) 533-538
12. Hoffman E.P., and Kunkel L.M. Dystrophin abnormalities in Duchenne/Becker muscular dystrophy. Neuron 2 (1989) 1019-1029
13. D'Angelo M.G., and Bresolin N. Cognitive impairment in neuromuscular disorders. Muscle Nerve 34 (2006) 16-33
14. Karagan N.J., and Sorensen J.P. Intellectual functioning in non-Duchenne muscular dystrophy. Neurology 31 (1981) 448-452
15. England S.B., Nicholson L.V., Johnson M.A., et al. Very mild muscular dystrophy associated with the deletion of 46% of dystrophin. Nature 343 (1990) 180-182
16. Ragot T., Vincent N., Chafey P., et al. Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice. Nature 361 (1993) 647-650
17. Wells D.J., Wells K.E., Asante E.A., et al. Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy. Hum Mol Genet 4 (1995) 1245-1250
18. Phelps S.F., Hauser M.A., Cole N.M., et al. Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice. Hum Mol Genet 4 (1995) 1251-1258
19. Le Gal La Salle G., Robert J.J., Berrard S., et al. An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259 (1993) 988-990
20. Miyake S., Makimura M., Kanegae Y., et al. Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc Natl Acad Sci USA 93 (1996) 1320-1324
21. Banker G.A., and Cowan W.M. Rat hippocampal neurons in dispersed cell culture. Brain Res 126 (1977) 342-397
22. Maccioni R.B., and Cambiazo V. Role of microtubule-associated proteins in the control of microtubule assembly. Physiol Rev 75 (1995) 835-864
23. Cho K.O., Hunt C.A., and Kennedy M.B. The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron 9 (1992) 929-942
24. Cowan D., Linial M., and Scheller R.H. Torpedo synaptophysin: evolution of a synaptic vesicle protein. Brain Res 509 (1990) 1-7
25. Leimer U., Franke W.W., and Leube R.E. Synthesis of the mammalian synaptic vesicle protein synaptophysin in insect cells: a model for vesicle biogenesis. Exp Cell Res 224 (1996) 88-95
26. Emery A.E.H. Duchenne muscular dystrophy. 2nd ed. (1993), Oxford University Press, Oxford
27. Koenig M., Beggs A.H., Moyer M., et al. The molecular basis for Duchenne versus Becker muscular dystrophy: correlation of severity with type of deletion. Am J Hum Genet 45 (1989) 498-506
28. Emery A.E. Clinical and molecular studies in Duchenne muscular dystrophy. Prog Clin Biol Res 306 (1989) 15-28
29. Arahata K., Ishiura S., Ishiguro T., et al. Immunostaining of skeletal and cardiac muscle surface membrane with antibody against Duchenne muscular dystrophy peptide. Nature 333 (1988) 861-863
30. Hoffman E.P., Fischbeck K.H., Brown R.H., et al. Characterization of dystrophin in muscle-biopsy specimens from patients with Duchenne's or Becker's muscular dystrophy. N Engl J Med 318 (1988) 1363-1368
31. Zubrzycka-Gaarn E.E., Bulman D.E., Karpati G., et al. The Duchenne muscular dystrophy gene product is localized in sarcolemma of human skeletal muscle. Nature 333 (1988) 466-469
32. Hemmings L., Kuhlman P.A., and Critchley D.R. Analysis of the actin-binding domain of alpha-actinin by mutagenesis and demonstration that dystrophin contains a functionally homologous domain. J Cell Biol 116 (1992) 1369-1380
33. Suzuki A., Yoshida M., Hayashi K., et al. Molecular organization at the glycoprotein-complex-binding site of dystrophin. Three dystrophin-associated proteins bind directly to the carboxy-terminal portion of dystrophin. Eur J Biochem 220 (1994) 283-292
34. Lidov H.G., Byers T.J., and Kunkel L.M. The distribution of dystrophin in the murine central nervous system: an immunocytochemical study. Neuroscience 54 (1993) 167-187
35. Brunig I., Suter A., Knuesel I., et al. GABAergic terminals are required for postsynaptic clustering of dystrophin but not of GABA(A) receptors and gephyrin. J Neurosci 22 (2002) 4805-4813
36. D'Souza V.N., Nguyen T.M., Morris G.E., et al. A novel dystrophin isoform is required for normal retinal electrophysiology. Hum Mol Genet 4 (1995) 837-842
37. Lidov H.G., Selig S., and Kunkel L.M. Dp140: a novel 140 kDa CNS transcript from the dystrophin locus. Hum Mol Genet 4 (1995) 329-335
38. Byers T.J., Lidov H.G., and Kunkel L.M. An alternative dystrophin transcript specific to peripheral nerve. Nat Genet 4 (1993) 77-81
39. Rapaport D., Fuchs O., Nudel U., et al. Expression of the Duchenne muscular dystrophy gene products in embryonic stem cells and their differentiated derivatives. J Biol Chem 267 (1992) 21289-21292
40. Lenk U., Oexle K., Voit T., et al. A cysteine 3340 substitution in the dystroglycan-binding domain of dystrophin associated with Duchenne muscular dystrophy, mental retardation and absence of the ERG b-wave. Hum Mol Genet 5 (1996) 973-975
41. Moizard M.P., Toutain A., Fournier D., et al. Severe cognitive impairment in DMD: obvious clinical indication for Dp71 isoform point mutation screening. Eur J Hum Genet 8 (2000) 552-5526
42. Sudol M., Bork P., Einbond A., et al. Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain. J Biol Chem 270 (1995) 14733-14741
43. Vaillend C., and Ungerer A. Behavioral characterization of mdx3cv mice deficient in C-terminal dystrophins. Neuromuscul Disord 9 (1999) 296-304
44. Ishikawa-Sakurai M., Yoshida M., Imamura M., et al. ZZ domain is essentially required for the physiological binding of dystrophin and utrophin to beta-dystroglycan. Hum Mol Genet 13 (2004) 693-702