Granulocyte macrophage-colony stimulating factor (GM-CSF) augments acute lung injury via its neutrophil priming effects

Journal of Korean Medical Science

Volumn 23, Issue 2, 2008, Pages 288-295

  Jae, Chol Choi ^a   Jae, Woo Jung ^a   Hee, Won Kwak ^a   Ju, Han Song ^a   Eun, Ju Jeon ^a   Jong, Wook Shin ^a   In, Won Park ^a   Byoung, Whui Choi ^a   Jae, Yeol Kim ^a,b  

^a Chung Ang University   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

Author keywords

Adult, respiratory distress syndrome; Granulocyte macrophage colony stimulating factor; Hemorrhage; Lipopolysaccharides; Neutrophils

Indexed keywords

CXCL2 CHEMOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PEROXIDASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BONE MARROW CELL; C57BL MOUSE; CYTOLOGY; INJURY; LUNG; MALE; METABOLISM; MOUSE; NEUTROPHIL; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; BONE MARROW CELLS; CHEMOKINE CXCL2; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUTROPHILS; PEROXIDASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 43449121891     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2008.23.2.288     Document Type: Article

References (17)

1. Fibbe WC, Daha MR, Hiemstra PS, Duinkerken N, Lurvink E, Ralph P, Altrock BW, Kaushansky K, Willemze R, Falkenburg JH. Interleukin1 and poly(rl)poly(rC) induce production of granulocyt CSF, macrophage CSF and granulocyte-macrophage CSF by human endothelial cells. Exp Hematol 1989; 17: 229-34.
2. Strieter RM, Kunkel SL, Showell HJ, Remick DG, Phan SH, Ward PA, Marks RM. Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 beta. Science 1989; 243: 1467-9.
3. Gasson JC, Weisbart RH, Kaufman SE, Clark SC, Hewick RM, Wong GG, Golde DW. Purified human granulocyte-macrophage colony-stimulating factor: direct effects on neutrophils. Science 1984; 226: 1339-42.
4. Weisbart RH, Golde DW, Clark SC, Wong GG, Gasson JC. Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator. Nature 1985; 314: 361-3.
5. Arnberg H, Letocha H, Nou F, Westlin JF, Nilsson S. GM-CSF in chemotherapy-induced febrile neutropenia - a double-blind randomized study. Anticancer Res 1998; 18: 1255-60.
6. Lopez AF, Williamson DJ, Gamble JR, Begley CG, Harlan JM, Klebanoff SJ, Waltersdorph A, Wong G, Clark SC, Vadas MA. Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. J Clin Invest 1986; 78: 1220-8.
7. Verhoef G, Boogaerts M. Treatment with granulocyte-macrophage colony-stimulating factor and the adult respiratory distress syndrome. Am J Hematol 1991; 36: 285-7.
8. Tiegs G, Barsig J, Matiba B, Uhlig S, Wendel A. Potentiation by granulocyte macrophage colony-stimulating factor of lipopolysaccharide toxicity in mice. J Clin Invest 1994; 93: 2616-22.
9. Sauaia A, Moore FA, Moore EE, Lezotte DC. Early risk factors for postinjury multiple organ failure. World J Surg 1996; 20: 392-400.
10. Dranoff G, Crawford AD, Sadelain M, Ream B, Rashid A, Bronson RT, Dickersin GR, Bachurski CJ, Mark EL, Whitsett JA. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science 1994; 264: 713-6.
11. Kim JY, Park JS, Strassheim S, Douglas I, del Valle FD, Asehnoune K, Mitra S, Kwak SH, Yamada S, Maruyama I, Ishizaka A, Abraham E. HMGB1 contributes to the development of acute lung injury after hemorrhage. Am J Physiol Lung Cell Mol Physiol 2005; 288: L958-65.
12. Pelaez A, Bechara RI, Joshi PC, Brown LA, Guidot DM. Granulo cyte/macrophage colony-stimulating factor treatment improves alveolar epithelial barrier function in alcoholic rat lung. Am J Physiol Lung Cell Mol Physiol 2004; 286: L106-11.
13. Orozco H, Arch J, Medina-Franco H, Pantoja JP, Gonzalez QH, Vilatoba M, Hinojosa C, Vargas-Vorackova F, Sifuentes-Osornio J. Molgramostim (GM-CSF) associated with antibiotic treatment in nontraumatic abdominal sepsis: a randomized, double-blind, placebo-controlled clinical trial. Arch Surg 2006; 141: 150-3.
14. Basu S, Dunn AR, Marino MW, Savoia H, Hodgson G, Lieschke GJ, Cebon J. Increased tolerance to endotoxin by granulocyte-macrophage colony-stimulating factor-deficient mice. J Immunol 1997; 159: 1412-7.
15. Kamiya K, Kono T, Iwamoto J, Yoneda M, Kotani H, Kasai S. The cytoprotective role of lipopolysaccharide-induced nitric oxide against liver damage during early phase of endotoxemia in rats. Shock 2000; 14: 229-33.
16. LeVine AM, Reed JA, Kurak KE, Cianciolo E, Whitsett JA. GMCSF-deficient mice are susceptible to pulmonary group B streptococcal infection. J Clin Invest 1999; 103: 563-9.
17. Abraham E, Nick JA, Azam T, Kim SH, Mira JP, Svetkauskaite D, He Q, Zamora M, Murphy J, Park JS. Overdier K, Dinarello CA. Peripheral blood neutrophil activation patterns are associated with pulmonary inflammatory responses to lipopolysaccharide in humans. J Immunol 2006; 176: 7753-60.