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Volumn 86, Issue 6, 2008, Pages 659-662

Aliskiren - Mode of action and preclinical data

Author keywords

Hypertension; Renin; Renin angiotensin system

Indexed keywords

ALISKIREN; EPLERENONE; LOSARTAN; PERINDOPRIL; SPIRONOLACTONE; VALSARTAN;

EID: 43449112039     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-008-0330-6     Document Type: Review
Times cited : (33)

References (18)
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    • Muller DN, Luft FC (2006) Direct renin inhibition with aliskiren in hypertension and target organ damage. Clin J Am Soc Nephrol 1(2):221-228
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 221-228
    • Muller, D.N.1    Luft, F.C.2
  • 4
    • 0022454787 scopus 로고
    • Elevated plasma renin activity associated with renal dysfunction
    • 1
    • Kehoe B, Keeton GR, Hill C (1986) Elevated plasma renin activity associated with renal dysfunction. Nephron 44(1):51-57
    • (1986) Nephron , vol.44 , pp. 51-57
    • Kehoe, B.1    Keeton, G.R.2    Hill, C.3
  • 5
    • 0036878284 scopus 로고    scopus 로고
    • Relationships between left ventricular mass and the renin-angiotensin system, catecholamines, insulin and leptin
    • 5
    • Malmqvist K, Ohman KP, Lind L, Nystrom F, Kahan T (2002) Relationships between left ventricular mass and the renin-angiotensin system, catecholamines, insulin and leptin. J Intern Med 252(5):430-439
    • (2002) J Intern Med , vol.252 , pp. 430-439
    • Malmqvist, K.1    Ohman, K.P.2    Lind, L.3    Nystrom, F.4    Kahan, T.5
  • 6
    • 0346059331 scopus 로고    scopus 로고
    • Plasma renin activity levels in hypertensive persons: Their wide range and lack of suppression in diabetic and in most elderly patients
    • 1
    • Alderman MH, Cohen HW, Sealey JE, Laragh JH (2004) Plasma renin activity levels in hypertensive persons: their wide range and lack of suppression in diabetic and in most elderly patients. Am J Hypertens 17(1):1-7
    • (2004) Am J Hypertens , vol.17 , pp. 1-7
    • Alderman, M.H.1    Cohen, H.W.2    Sealey, J.E.3    Laragh, J.H.4
  • 16
    • 0036372173 scopus 로고    scopus 로고
    • Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): Comparison with enalapril
    • 1
    • Nussberger J, Wuerzner G, Jensen C, Brunner HR (2002) Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): comparison with enalapril. Hypertension 39(1):E1-E8
    • (2002) Hypertension , vol.39
    • Nussberger, J.1    Wuerzner, G.2    Jensen, C.3    Brunner, H.R.4
  • 17
    • 34848907212 scopus 로고    scopus 로고
    • Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats
    • 11
    • Kelly DJ, Zhang Y, Moe G, Naik G, Gilbert RE (2007) Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats. Diabetologia 50(11):2398-2404
    • (2007) Diabetologia , vol.50 , pp. 2398-2404
    • Kelly, D.J.1    Zhang, Y.2    Moe, G.3    Naik, G.4    Gilbert, R.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.