Spatial Regulation of nanos Is Required for Its Function in Dendrite Morphogenesis

Current Biology

Volumn 18, Issue 10, 2008, Pages 745-750

  Brechbiel, Jillian L ^a   Gavis, Elizabeth R ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

CELLBIO; CELLNEURO; RNA

Indexed keywords

DROSOPHILA PROTEIN; GLORUND PROTEIN, DROSOPHILA; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; MESSENGER RNA; NANOS PROTEIN, DROSOPHILA; REPRESSOR PROTEIN; RNA BINDING PROTEIN; SMG PROTEIN, DROSOPHILA;

3' UNTRANSLATED REGION; ANIMAL; ARTICLE; DENDRITE; DROSOPHILA; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MORPHOGENESIS; PERIPHERAL NERVOUS SYSTEM; PHYSIOLOGY; PROTEIN DOMAIN;

3' UNTRANSLATED REGIONS; ANIMALS; DENDRITES; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP F-H; MORPHOGENESIS; PERIPHERAL NERVOUS SYSTEM; PROTEIN INTERACTION DOMAINS AND MOTIFS; REPRESSOR PROTEINS; RNA, MESSENGER; RNA-BINDING PROTEINS;

EID: 43449111190     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2008.04.033     Document Type: Article

References (34)

1. Ye B., Petritsch C., Clark I.E., Gavis E.R., Jan L.Y., and Jan Y.N. nanos and pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. Curr. Biol. 14 (2004) 314-321
2. Lehmann R., and Nusslein-Volhard C. The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo. Development 112 (1991) 679-691
3. Gavis E.R., and Lehmann R. Localization of nanos RNA controls embryonic polarity. Cell 71 (1992) 301-313
4. Forrest K.M., and Gavis E.R. Live imaging of endogenous mRNA reveals a diffusion and entrapment mechanism for nanos mRNA localization in Drosophila. Curr. Biol. 13 (2003) 1159-1168
5. Gavis E.R., and Lehmann R. Translational regulation of nanos by RNA localization. Nature 369 (1994) 315-318
6. Grueber W.B., Jan L.Y., and Jan Y.N. Tiling of the Drosophila epidermis by multidendritic sensory neurons. Development 129 (2002) 2867-2878
7. Gao F.B., Brenman J.E., Jan L.Y., and Jan Y.N. Genes regulating dendritic outgrowth, branching, and routing in Drosophila. Genes Dev. 13 (1999) 2549-2561
8. Grueber W.B., Ye B., Moore A.W., Jan L.Y., and Jan Y.N. Dendrites of distinct classes of Drosophila sensory neurons show different capacities for homotypic repulsion. Curr. Biol. 13 (2003) 618-626
9. Grueber W.B., Jan L.Y., and Jan Y.N. Different levels of the homeodomain protein Cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons. Cell 112 (2003) 805-818
10. Gavis E.R., Chatterjee S., Ford N.R., and Wolff L.J. Dispensability of nanos mRNA localization for abdominal patterning but not for germ cell development. Mech. Dev. 125 (2008) 81-90
11. Gavis E.R., Curtis D., and Lehmann R. Identification of cis-acting sequences that control nanos RNA localization. Dev. Biol. 176 (1996) 36-50
12. Weil T.T., Forrest K.M., and Gavis E.R. Localization of bicoid mRNA in late oocytes is maintained by continual active transport. Dev. Cell 11 (2006) 251-262
13. Rook M.S., Lu M., and Kosik K.S. CaMKIIalpha 3′ untranslated region-directed mRNA translocation in living neurons: visualization by GFP linkage. J. Neurosci. 20 (2000) 6385-6393
14. Knowles R.B., Sabry J.H., Martone M.E., Deerinck T.J., Ellisman M.H., Bassell G.J., and Kosik K.S. Translocation of RNA granules in living neurons. J. Neurosci. 16 (1996) 7812-7820
15. Kohrmann M., Luo M., Kaether C., DesGroseillers L., Dotti C.G., and Kiebler M.A. Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dendritic transport in living hippocampal neurons. Mol. Biol. Cell 10 (1999) 2945-2953
16. Kanai Y., Dohmae N., and Hirokawa N. Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. Neuron 43 (2004) 513-525
17. Rolls M.M., Satoh D., Clyne P.J., Henner A.L., Uemura T., and Doe C.Q. Polarity and intracellular compartmentalization of Drosophila neurons. Neural Develop. 2 (2007) 7
18. Bullock S.L., and Ish-Horowicz D. Conserved signals and machinery for RNA transport in Drosophila oogenesis and embryogenesis. Nature 414 (2001) 611-616
19. Wilkie G.S., and Davis I. Drosophila wingless and pair-rule transcripts localize apically by dynein-mediated transport of RNA particles. Cell 105 (2001) 209-219
20. Bergsten S.E., and Gavis E.R. Role for mRNA localization in translational activation but not spatial restriction of nanos RNA. Development 126 (1999) 659-669
21. Gavis E.R., Lunsford L., Bergsten S.E., and Lehmann R. A conserved 90 nucleotide element mediates translational repression of nanos RNA. Development 122 (1996) 2791-2800
22. Smibert C.A., Wilson J.E., Kerr K., and Macdonald P.M. Smaug protein represses translation of unlocalized nanos mRNA in the Drosophila embryo. Genes Dev. 10 (1996) 2600-2609
23. Dahanukar A., and Wharton R.P. The Nanos gradient in Drosophila embryos is generated by translational regulation. Genes Dev. 10 (1996) 2610-2620
24. Crucs S., Chatterjee S., and Gavis E.R. Overlapping but distinct RNA elements control repression and activation of nanos translation. Mol. Cell 5 (2000) 457-467
25. Forrest K.M., Clark I.E., Jain R.A., and Gavis E.R. Temporal complexity within a translational control element in the nanos mRNA. Development 131 (2004) 5849-5857
26. Smibert C.A., Lie Y.S., Shillingaw W., Henzel W.J., and Macdonald P.M. Smaug, a novel and conserved protein contributes to repression of nanos mRNA translation in vitro. RNA 5 (1999) 1535-1547
27. Kalifa Y., Huang T., Rosen L.N., Chatterjee S., and Gavis E.R. Glorund, an hnRNP F/H homolog, is an ovarian repressor of nanos translation. Dev. Cell 10 (2006) 291-301
28. Dahanukar A., Walker J.A., and Wharton R.P. Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila. Mol. Cell 4 (1999) 209-218
29. Duchow H.K., Brechbiel J.L., Chatterjee S., and Gavis E.R. The nanos translational control element represses translation in somatic cells by a Bearded box-like motif. Dev. Biol. 282 (2005) 207-217
30. Clark I.E., Duchow H.K., Vlasak A.N., and Gavis E.R. A common translational control mechanism functions in axial patterning and neuroendocrine signaling in Drosophila. Development 129 (2002) 3325-3334
31. Lee T., and Luo L. Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 22 (1999) 451-461
32. Sonoda J., and Wharton R.P. Recruitment of Nanos to hunchback mRNA by Pumilio. Genes Dev. 13 (1999) 2704-2712
33. Barker D.D., Wang C., Moore J., Dickinson L.K., and Lehmann R. Pumilio is essential for function but not for distribution of the Drosophila abdominal determinant Nanos. Genes Dev. 6 (1992) 2312-2326
34. Macdonald P.M. The Drosophila pumilio gene: an unusually long transcription unit and an unusual protein. Development 114 (1992) 221-232