Genetic markers of tumour necrosis factor α in aggressive and chronic periodontitis

Journal of Clinical Periodontology

Volumn 35, Issue 6, 2008, Pages 493-500

  Schulz, Susanne ^a,c   MacHulla, Helmut K G ^a   Altermann, Wolfgang ^a   Klapproth, Jana ^a   Zimmermann, Uta ^a   Gläser, Christiane ^a   Kluttig, Alexander ^a   Stein, Jamal ^b   Schaller, Hans Günter ^a   Reichert, Stefan ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c University School of Dental Medicine   (Germany)

Author keywords

Aggressive periodontitis; Chronic periodontitis; Haplotype; Tumour necrosis factor

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ACUTE DISEASE; ADULT; ARTICLE; CASE CONTROL STUDY; CHRONIC DISEASE; FEMALE; GENE FREQUENCY; GENETIC MARKER; GENETICS; HAPLOTYPE; HUMAN; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; MIDDLE AGED; PERIODONTICS; PERIODONTITIS; PREVOTELLA INTERMEDIA; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; STATISTICAL MODEL;

ACUTE DISEASE; ADULT; CASE-CONTROL STUDIES; CHRONIC DISEASE; FEMALE; GENE FREQUENCY; GENETIC MARKERS; HAPLOTYPES; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; PERIODONTAL INDEX; PERIODONTITIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREVOTELLA INTERMEDIA; SMOKING; TUMOR NECROSIS FACTOR-ALPHA;

EID: 43449111189     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2008.01226.x     Document Type: Article

References (52)

1. Albandar, J. M. (2005) Epidemiology and risk factors of periodontal diseases. Dental clinics of North America 49, 517 532.
2. Bodet, C., Chandad, F. Grenier, D. (2006a) Porphyromonas gingivalis-induced inflammatory mediator profile in an ex vivo human whole blood model. Clinical and Experimental Immunology 143, 50 57.
3. Bodet, C., Chandad, F. Grenier, D. (2006b) Inflammatory responses of a macrophage/epithelial cell co-culture model to mono and mixed infections with Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia. Microbes and Infection 8, 27 35.
4. Borish, L. C. Steinke, J. W. (2003) Cytokines and chemokines. Journal of Allergy and Clinical Immunology 111, 460 475.
5. Cordell, H. J. Clayton, D. G. (2005) Genetic association studies. The Lancet 366, 1121 1131.
6. Cortelli, J. R., Cortelli, S. C., Jordan, S., Haraszthy, V. I. Zambon, J. J. (2005) Prevalence of periodontal pathogens in Brazilians with aggressive or chronic periodontitis. Journal of Clinical Periodontology 32, 860 866.
7. Craandijk, J., van Krugten, M. V., Verweij, C. L., van der Velden, U. Loos, B. G. (2002) Tumor necrosis factor-alpha gene polymorphisms in relation to periodontitis. Journal of Clinical Periodontology 29, 28 34.
8. Cuenca, J., Cuchacovich, M., Perez, C., Ferreira, L., Aguirre, A., Schiattino, I., Soto, L., Cruzat, A., Salazar-Onfray, F. Aguillon, J. C. (2003) The -308 polymorphism in tumour necrosis factor (TNF) gene promoter region and ex vivo lipopolysaccharide-induced TNF expression and cytotoxic activity in Chilean patients with rheumatoid arthritis. Rheumatology 42, 308 313.
9. Cuenca, J., Perez, C., Aguirre, A., Schiattino, I. Aguillon, J. C. (2001) Genetic polymorphism at position -308 in the promoter region of the tumor necrosis factor (TNF): implications of its allelic distribution on susceptibility or resistance to disease in Chilean population. Biological Research 34, 237 241.
10. Deshpande, A., Nolan, J. P., White, P. S., Valdez Y, E., Hunt, W. C., Peyton, C. L. Wheeler, C. M. (2005) TNF-α promoter polymorphisms and susceptibility to human papillomavirus 16-associated cervical cancer. The Journal of Infectious Diseases 191, 969 976.
11. Donati, M., Berglundh, T., Hytönen, A.-M., Hahn-Zoric, M., Hanson, L.-A. Padyukov, L. (2005) Association of the -159CD14 gene polymorphism and lack of association of the -308TNFA and Q551R IL-4RA polymorphisms with sever chronic periodontitis in Swedish Caucasians. Journal of Clinical Periodontitis 32, 474 479.
12. D'Aiuto, F., Parkar, M., Brett, P. M., Ready, D. Tonetti, M. S. (2004) Gene polymorphisms in pro-inflammatory cytokines are associated with systemic inflammation in patients with severe periodontal infections. Cytokine 28, 29 34.
13. D'Aiuto, F., Parkar, M. Tonetti, M. S. (2005) Periodontal therapy: a novel acute inflammatory model. Inflammation Research 54, 412 414.
14. D'Aiuto, F., Parkar, M. Tonetti, M. S. (2007) Acute effects of periodontal therapy on bio-markers of vascular health. Journal of Clinical Periodontology 34, 124 129.
15. Endo, M., Tai, H., Tabeta, K., Kabayashi, T., Yamazaki, K. Yoshie, H. (2001) Analysis of single nucleotide polymorphisms in the 5′-flanking region of tumor necrosis factor-alpha gene in Japanese patients with early-onset periodontitis. Journal of Periodontology 72, 1554 1559.
16. Engebretson, S., Chertog, R., Nichols, A., Hey-Hadavi, J., Celenti, R. Grbic, J. (2007) Plasma levels of tumour necrosis factor-α in patients with chronic periodontitis and type 2 diabetes. Journal of Clinical Periodontology 34, 18 24.
17. Fassmann, A., Holla, L. I., Buckova, D., Vasku, A., Zojil, V. Vanek, J. (2003) Polymorphisms in the +252(A/G) lymphotoxin-alpha and the -308(A/G) tumor necrosis factor-alpha genes and susceptibility to chronic periodontitis in a Czech population. Journal of Periodontal Research 38, 394 399.
18. Feng, J., Aboyoussef, H., Weiner, S., Singh, S. Jandinski, J. (2006) The effect of gingival retraction procedures on periodontal indices and crevicular fluid cytokine levels: a pilot study. Journal of Prosthodontics 15, 108 112.
19. Folwaczny, M., Glas, J., Torok, H. P., Mende, M. Folwaczny, C. (2004) Lack of association between the TNF alpha G-308 a promoter polymorphism and periodontal disease. Journal of Clinical Periodontology 31, 449 453.
20. Galbraith, G. M., Hendley, T. M., Sanders, J. J., Palesch, Y. Pandley, J. P. (1999) Polymorphic cytokine genotypes as markers of disease severity in adult periodontitis. Journal of Clinical Periodontology 26, 705 709.
21. Galbraith, G. M., Steed, R. B., Sanders, J. J. Pandey, J. P. (1998) Tumor necrosis factor alpha production by oral leukocytes: influence of tumor necrosis factor genotype. Journal of Clinical Periodontology 69, 428 433.
22. Gonzalez, S., Rodrigo, L., Martinez-Borra, J., Lopez-Vazquez, A., Fuentes, D., Nino, P., Cadahia, V., Saro, C., Dieguez, M. A. Lopez-Larrea, C. (2003) TNF-α -308 promoter polymorphism is associated with enhanced TNF-α production and inflammatory activity in Crohn's patients with fistulizing disease. American Journal of Gastroenterology 98, 1101 1106.
23. Graves, D. T. Cochran, D. (2003) The contribution of interleukin-1 and tumor necrosis factor to periodontal tissue destruction. Journal of Peridontology 74, 391 401.
24. Havemose-Poulsen, A., Sorensen, L. K., Stolte, K., Bendtzen, K. Holmstrup, P. (2005) Cytokine profiles in peripheral blood and whole blood cell cultures associated with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis. Journal of Periodontology 76, 2276 2285.
25. Heasman, L., Stacey, F., Preshaw, P. M., McCracken, G. I., Hepburn, S. Heasman, P. A. (2006) The effect of smoking on periodontal treatment response: a review of clinical evidence. Journal of Clinical Periodontology 33, 241 253.
26. Honda, T., Domon, H., Okui, T., Kajita, K., Amanuma, R. Yamazaki, K. (2006) Balance of inflammatory response in stable gingivitis and progressive periodontitis lesions. Clinical and Experimental Immunology 144, 35 40.
27. Hong, C. Y., Lin, S. K., Kok, S. H., Cheng, S. J., Lee, M. S., Wang, T. M., Chen, C. S., Lin, L. D. Wang, J. S. (2004) The role of lipopolysaccharide in infectious bone resorption of periapical lesion. Journal of Oral Pathology and Medicine 33, 162 169.
28. Hosokawa, Y., Hosokawa, I., Ozaki, K., Nakae, H. Matsuo, T. (2005) Increase of CCL20 expression by human gingival fibroblasts upon stimulation with cytokines and bacterial endotoxin. Clinical and Experimental Immunology 142, 285 291.
29. Ikezawa, I., Tai, H., Shimada, Y., Komatsu, Y., Galicia, J. C. Yoshie, H. (2005) Imbalance between soluble tumour necrosis factor receptors type 1 and 2 in chronic periodontitis. Journal of Clinical Periodontology 32, 1047 1054.
30. Kornman, K. S., Crane, A., Wang, H. Y., di Giovine, F. S., Newman, M. G., Pirk, F. W., Wilson, T. G., Higginbottom, F. L. Duff, G. W. (1997) The interleukin-1 genotype as a severity factor in adult periodontal disease. Journal of Clinical Periodontology 24, 72 77.
31. Kurtis, B., Tuter, G., Serdar, M., Akdemir, P., Uygur, C., Firatli, E. Bal, B. (2005) Gingival crevicular fluid levels of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha in patients with chronic and aggressive periodontitis. Journal of Periodontology 76, 1849 1855.
32. Lange, D. E., Plagmann, H. C., Eenboom, A. Promesberger, A. (1977) Clinical methods for the objective evaluation of oral hygiene. Deutsche Zahnärztliche Zeitschrift 32, 44 47.
33. Lima, V., Vidal, F. D., Rocha, F. A., Brito, G. A. Ribeiro, R. A. (2004) Effects of tumor necrosis factor-alpha inhibitors pentoxifylline and thalidomide on alveolar bone loss in short-term experimental periodontal disease in rats. Journal of Periodontology 75, 162 168.
34. Lin, L., Pan, Y. P. Yin, L. Y. (2003) Study on the correlation of cytokine gene polymorphism with chronic periodontitis. Shanghai Kou Qiang Yi Xue 12, 456 459.
35. Loos, B. G., John, R. P. Laine, M. L. (2005) Identification of genetic risk factors for periodontitis and possible mechanisms of action. Journal of Clinical Periodontology 32 (Suppl. 6), 159 179.
36. Michalowicz, B. S., Diehl, S. R., Gunsolley, J. C., Sparks, B. S., Brooks, C. N., Koertge, T. E., Califano, J. V., Burmeister, J. A. Schenkein, H. A. (2000) Evidence of a substantial genetic basis for risk of adult periodontitis. Journal of Periodontology 71, 1699 1707.
37. Palmer, R. M., Wilson, R. F., Hasan, A. S. Scott, D. A. (2005) Mechanisms of activation of environmental factors - tobacco smoking. Journal of Clinical Periodontology 32, 180 195.
38. Perez, C., Gonzalez, F. E., Pavez, V., Araya, A. V., Aquirre, A., Cruzat, A., Contreras-Levicoy, J., Dotte, A., Aravena, O., Salazar, L., Catalan, D., Cuence, J., Ferreira, A., Schiattino, I. Aquillon, J. C. (2004) The -308 polymorphism in the promoter region of tumor necrosis factor-alpha (TNF-alpha) gene and ex vivo lipopolysaccharide-induced TNF-alpha expression in patients with aggressive periodontitis and/or type 1 diabetes mellitus. European Cytokine Network 15, 364 370.
39. Pihlstrom, B. L., Michalowicz, B. S. Johnson, N. W. (2005) Periodontal diseases. Lancet 366, 1809 1820.
40. Rahman, M. M. McFadden, G. (2006) Modulation of Tumor necrosis factor by microbial pathogens. PLoS Pathogens 2, 66 77.
41. Reichert, S., Stein, J., Gautsch, A., Schaller, H. G. Machulla, H. K. G. (2003) Gender differences in HLA phenotype frequencies found in German patients with generalized aggressive periodontitis and chronic periodontitis. Oral Microbiology and Immunology 17, 360 368.
42. Sakellari, D., Katsares, V., Georgiadou, M., Kouvatsi, A., Arsenakis, M. Konstantinidis, A. (2006) No correlation of five polymorphisms with periodontal conditions in a Greek population. Journal of Clinical Periodontology 33, 765 770.
43. Scapoli, C., Mamolini, E. Trombelli, L. (2007) Role of IL-6, TNF-A and LT-A variants in the modulation of the clinical expression of plaque-induced gingivitis. Journal of Clinical Periodontitis 34, 1031 1038.
44. Schulz, S., Schagdarsurengin, U., Müller-Werdan, U., Werdan, K. Gläser, C. (2004) Relation between TNF-α gene and protein expression and clinical, biochemical, and genetic markers: age, body mass index and uric acid are independent predictors for an elevated TNF-α plasma level in a complex risk model. European Cytokine Network 15, 105 111.
45. Schulz, S., Schagdarsurengin, U., Rehlefd, D., Süß, T., Werdan, K., Müller-Werdan, U. Gläser, C. (2006) Genetic impact of TNF-β on risk factors for coronary atherosclerosis. European Cytokine Network 17, 148 154.
46. Shapira, L., Stabholz, A., Rieckmann, P. Kruse, N. (2001) Genetic polymorphism of the tumor necrosis factor (TNF)-alpha promoter region in families with localized early-onset periodontitis. Journal of Periodontal Research 36, 183 186.
47. Shapira, L., Wilensky, A. Kinane, D. F. (2005) Effect of genetic variabilità on the inflammatory response to periodontal infection. Journal of Clinical Periodontitis 32, 72 86.
48. Soga, Y., Nishimura, F., Ohyama, H., Maeda, H., Takashiba, S. Murayama, Y. (2003) Tumor necrosis factor-alpha gene (TNF-α) -1031/-863, -857 single-nucleotide polymorphisms (SNPs) are associated with severe adult periodontitis in Japanese. Journal of Clinical Periodontitis 30, 524 531.
49. Timmerman, M. F. van der Weijden, G. A. (2006) Risk factors for periodontitis. International Journal of Dental Hygiene 4, 2 7.
50. Trevilatto, P. C., Tramontina, V. A., Machado, M. A. N., Goncalves, R. B., Sallum, A. W. Line, S. R. P. (2002) Clinical, genetic and microbiological findings in a Brazilian family with aggressive periodontitis. Journal of Clinical Periodontology 29, 233 239.
51. Wang, W. Y. S., Baratt, B. J., Clayton, D. G. Todd, J. A. (2005) Genome-wide association studies: theoretical and practical concerns. Nature Reviews 6, 109 118.
52. Yoshie, H., Kobayashi, T., Tai, H. Galicia, J. C. (2007) The role of genetic polymorphisms in periodontitis. Periodontology 2000 43, 102 132.