메뉴 건너뛰기




Volumn 237, Issue 5, 2008, Pages 1295-1306

PAX6 dosage effects on corneal development, growth, and wound healing

Author keywords

Anterior segment; Cornea; Gene dosage; Pax6; Wound healing

Indexed keywords

BROXURIDINE; CYCLIN E; CYTOKERATIN 12; HISTONE H3; PHOSPHOHISTONE 3; PROTEIN P63; TRANSCRIPTION FACTOR PAX6;

EID: 43449103925     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21528     Document Type: Article
Times cited : (45)

References (52)
  • 1
    • 0030671068 scopus 로고    scopus 로고
    • Tandem duplication of 11p12-p13 in a child with borderline development delay and eye abnormalities: Dose effect of the PAX6 gene product
    • Aalfs CM, Fantes JA, Wenniger-Prick LJ, Sluijter S, Hennekam RC, van Heyningen V. 1997. Tandem duplication of 11p12-p13 in a child with borderline development delay and eye abnormalities: dose effect of the PAX6 gene product. Am J Med Genet 73:267-271.
    • (1997) Am J Med Genet , vol.73 , pp. 267-271
    • Aalfs, C.M.1    Fantes, J.A.2    Wenniger-Prick, L.J.3    Sluijter, S.4    Hennekam, R.C.5    van Heyningen, V.6
  • 2
    • 0036805779 scopus 로고    scopus 로고
    • Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities
    • Baulmann DC, Ohlmann A, Flugel-Koch C, Goswami S, Cvekl A, Tamm ER. 2002. Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities. Mech Dev 118:3-17.
    • (2002) Mech Dev , vol.118 , pp. 3-17
    • Baulmann, D.C.1    Ohlmann, A.2    Flugel-Koch, C.3    Goswami, S.4    Cvekl, A.5    Tamm, E.R.6
  • 3
    • 0034113512 scopus 로고    scopus 로고
    • Mutation in the PAX6 gene in twenty patients with aniridia
    • Chao LY, Huff V, Strong LC, Saunders GF. 2000. Mutation in the PAX6 gene in twenty patients with aniridia. Hum Mutat 15:332-339.
    • (2000) Hum Mutat , vol.15 , pp. 332-339
    • Chao, L.Y.1    Huff, V.2    Strong, L.C.3    Saunders, G.F.4
  • 4
    • 0037192827 scopus 로고    scopus 로고
    • Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays
    • Chauhan BK, Reed NA, Zhang W, Duncan MK, Kilimann MW, Cvekl A. 2002a. Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays. J Biol Chem. 277:11539-11548.
    • (2002) J Biol Chem , vol.277 , pp. 11539-11548
    • Chauhan, B.K.1    Reed, N.A.2    Zhang, W.3    Duncan, M.K.4    Kilimann, M.W.5    Cvekl, A.6
  • 5
    • 0036914491 scopus 로고    scopus 로고
    • A comparative cDNA microarray analysis reveals a spectrum of genes regulated by Pax6 in mouse lens
    • Chauhan BK, Reed NA, Yang Y, Cermak L, Reneker L, Duncan MK, Cvekl A. 2002b. A comparative cDNA microarray analysis reveals a spectrum of genes regulated by Pax6 in mouse lens. Genes to Cells 7:1267-1283.
    • (2002) Genes to Cells , vol.7 , pp. 1267-1283
    • Chauhan, B.K.1    Reed, N.A.2    Yang, Y.3    Cermak, L.4    Reneker, L.5    Duncan, M.K.6    Cvekl, A.7
  • 11
    • 0024523631 scopus 로고    scopus 로고
    • Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
    • Cotsarelis G, Cheng S-Z, Dong G, Sun T-T, Lavker R M. 1996. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell 57:201-209.
    • (1996) Cell , vol.57 , pp. 201-209
    • Cotsarelis, G.1    Cheng, S.-Z.2    Dong, G.3    Sun, T.-T.4    Lavker, R.M.5
  • 12
    • 84981840744 scopus 로고
    • The role of intraocular pressure in the development of the chick eye. I. Control of eye size
    • Coulombre AJ. 1956. The role of intraocular pressure in the development of the chick eye. I. Control of eye size. J Exp Zool 133:211-215.
    • (1956) J Exp Zool , vol.133 , pp. 211-215
    • Coulombre, A.J.1
  • 13
    • 0342513614 scopus 로고
    • The role of intraocular pressure in the development of the chick eye. II. Control of corneal size
    • Coulombre AJ. 1957. The role of intraocular pressure in the development of the chick eye. II. Control of corneal size. Arch Ophthalmol 57:250-254.
    • (1957) Arch Ophthalmol , vol.57 , pp. 250-254
    • Coulombre, A.J.1
  • 14
    • 0001912623 scopus 로고
    • Lens development. I. Role of the lens in eye growth
    • Coulombre AJ, Coulombre JL. 1964. Lens development. I. Role of the lens in eye growth. J Exp Zool 156:39-42.
    • (1964) J Exp Zool , vol.156 , pp. 39-42
    • Coulombre, A.J.1    Coulombre, J.L.2
  • 15
    • 0038010517 scopus 로고    scopus 로고
    • Requirement for Pax6 in corneal morphogenesis: A role in adhesion
    • Davis J, Duncan MK, Robison WG Jr, Piatigorsky J. 2003. Requirement for Pax6 in corneal morphogenesis: a role in adhesion. J Cell Sci 116:2157-2167.
    • (2003) J Cell Sci , vol.116 , pp. 2157-2167
    • Davis, J.1    Duncan, M.K.2    Robison Jr, W.G.3    Piatigorsky, J.4
  • 16
    • 6544265960 scopus 로고
    • A series of reviews on the biochemistry and biology of Cdc2/28-cyclin complexes
    • Draetta G. 1991. A series of reviews on the biochemistry and biology of Cdc2/28-cyclin complexes. Semin Cell Biol 2:193-271.
    • (1991) Semin Cell Biol , vol.2 , pp. 193-271
    • Draetta, G.1
  • 17
    • 0033786113 scopus 로고    scopus 로고
    • Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression
    • Duncan MK, Kozmik Z, Cveklova K, Piatigorsky J, Cvekl A. 2000. Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression. J Cell Sci 113:3173-3185.
    • (2000) J Cell Sci , vol.113 , pp. 3173-3185
    • Duncan, M.K.1    Kozmik, Z.2    Cveklova, K.3    Piatigorsky, J.4    Cvekl, A.5
  • 18
    • 0036177940 scopus 로고    scopus 로고
    • Proxl is differentially localized during lens development
    • Duncan MK, Cui W, Oh DJ, Tomareu I. 2002. Proxl is differentially localized during lens development. Mech Dev 112:195-198.
    • (2002) Mech Dev , vol.112 , pp. 195-198
    • Duncan, M.K.1    Cui, W.2    Oh, D.J.3    Tomareu, I.4
  • 20
    • 0028239775 scopus 로고
    • Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes
    • Epstein J, Cai J, Glaser T, Jepeal L, Maas R. 1994. Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes. J Biol Chem 269:8355-8361.
    • (1994) J Biol Chem , vol.269 , pp. 8355-8361
    • Epstein, J.1    Cai, J.2    Glaser, T.3    Jepeal, L.4    Maas, R.5
  • 22
    • 0029002548 scopus 로고
    • The role of Pax-6 in eye and nasal development
    • Grindley JC, Davidson DR, Hill RE. 1995. The role of Pax-6 in eye and nasal development. Development 121:1433-1442.
    • (1995) Development , vol.121 , pp. 1433-1442
    • Grindley, J.C.1    Davidson, D.R.2    Hill, R.E.3
  • 23
    • 0029999012 scopus 로고    scopus 로고
    • Ultrastructural, immunohistological and biochemical characterization of cultured mouse corneal epithelial cells
    • Hazlett L, Masinick S, Mezger B, Barrell R, Kurpakus M, Garrett M. 1996. Ultrastructural, immunohistological and biochemical characterization of cultured mouse corneal epithelial cells. Ophthalmic Res 28:50-56.
    • (1996) Ophthalmic Res , vol.28 , pp. 50-56
    • Hazlett, L.1    Masinick, S.2    Mezger, B.3    Barrell, R.4    Kurpakus, M.5    Garrett, M.6
  • 25
    • 0037226810 scopus 로고    scopus 로고
    • Management of aniridic keratopathy with keratolimbal allograft: A limbal stem cell transplantation technique
    • Holland EJ, Djalilian AR, Schwartz GS. 2003. Management of aniridic keratopathy with keratolimbal allograft: a limbal stem cell transplantation technique. Ophthalmology 110:125-130.
    • (2003) Ophthalmology , vol.110 , pp. 125-130
    • Holland, E.J.1    Djalilian, A.R.2    Schwartz, G.S.3
  • 27
    • 0031033915 scopus 로고    scopus 로고
    • The Pax-6 homeobox gene is expressed throughout the corneal and conjunctival epithelia
    • Koroma BM, Yang J, Sundin OH. 1997. The Pax-6 homeobox gene is expressed throughout the corneal and conjunctival epithelia. Invest Ophthalmol Vis Sci 38:108-120.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 108-120
    • Koroma, B.M.1    Yang, J.2    Sundin, O.H.3
  • 28
    • 34248181062 scopus 로고    scopus 로고
    • Cell surface glycoconjugate abnormalities and corneal epithelial wound healing in the pax6+/- mouse model of aniridia-related keratopathy
    • Kucerova R, Ou J, Leiper LJ, Collinson JM. 2006. Cell surface glycoconjugate abnormalities and corneal epithelial wound healing in the pax6+/- mouse model of aniridia-related keratopathy. Invest Ophthalmol Vis Sci. 47:5276-5282.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 5276-5282
    • Kucerova, R.1    Ou, J.2    Leiper, L.J.3    Collinson, J.M.4
  • 30
    • 0033104951 scopus 로고    scopus 로고
    • Corneal epithelium-specific mouse keratin K12 promoter
    • Liu JJ, Kao WW-Y, Wilson SE. 1999. Corneal epithelium-specific mouse keratin K12 promoter. Exp Eye Res 68:295-301.
    • (1999) Exp Eye Res , vol.68 , pp. 295-301
    • Liu, J.J.1    Kao, W.W.-Y.2    Wilson, S.E.3
  • 31
    • 0034935480 scopus 로고    scopus 로고
    • Corneal epithelial wound healing
    • Lu L, Reinach PS, Kao WW. 2001. Corneal epithelial wound healing. Exp Biol Med 226:653-664.
    • (2001) Exp Biol Med , vol.226 , pp. 653-664
    • Lu, L.1    Reinach, P.S.2    Kao, W.W.3
  • 32
    • 0025941907 scopus 로고
    • Introcular pressure-dependent and independent phases of growth of the embryonic chick eye and cornea
    • Neath P, Roche SM, Bee JA. 1991. Introcular pressure-dependent and independent phases of growth of the embryonic chick eye and cornea. Invest Ophthalmol Vis Sci 32:2483-2491.
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , pp. 2483-2491
    • Neath, P.1    Roche, S.M.2    Bee, J.A.3
  • 35
    • 33745639275 scopus 로고    scopus 로고
    • Pax6 overexpression suppresses cell proliferation and retards the cell cycle in corneal epithelial cells
    • Ouyang J, Shen Y-C, Yeh L-K, Li W, Liu CY, Fini E. 2006. Pax6 overexpression suppresses cell proliferation and retards the cell cycle in corneal epithelial cells. Invest Ophthalmol Vis Sci 47:2397-2407.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2397-2407
    • Ouyang, J.1    Shen, Y.-C.2    Yeh, L.-K.3    Li, W.4    Liu, C.Y.5    Fini, E.6
  • 38
    • 23944484521 scopus 로고    scopus 로고
    • Regulation of the Pax6: Pax6(5a) mRNA ratio in the developing mammalian brain
    • Pinson J, Simpson TI, Mason JO, Price DJ. 2005. Regulation of the Pax6: Pax6(5a) mRNA ratio in the developing mammalian brain. BMC Dev Biol 5:13.
    • (2005) BMC Dev Biol , vol.5 , pp. 13
    • Pinson, J.1    Simpson, T.I.2    Mason, J.O.3    Price, D.J.4
  • 41
    • 11144273257 scopus 로고    scopus 로고
    • Evolving concepts on the pathogenic mechanisms of aniridia related keratopathy
    • Ramaesh K, Ramaesh T, Dutton GN, Dhillon B. 2005b. Evolving concepts on the pathogenic mechanisms of aniridia related keratopathy. Int J Biochem Cell Biol 37:547-557.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 547-557
    • Ramaesh, K.1    Ramaesh, T.2    Dutton, G.N.3    Dhillon, B.4
  • 43
    • 0029882907 scopus 로고    scopus 로고
    • Apoptosis in the corneal epithelium
    • Ren H, Wilson G. 1996. Apoptosis in the corneal epithelium. Invest Ophthalmol Vis Sci 37:1017-1025.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 1017-1025
    • Ren, H.1    Wilson, G.2
  • 44
    • 0030581164 scopus 로고    scopus 로고
    • Influence of PAX6 gene dosage on development: Overexpression causes severe eye abnormalities
    • Schedl A, Ross A, Lee M, EngelKamp D, Rashbass P, van Heyningen V, Hastie ND. 1996. Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities. Cell 86:71-82.
    • (1996) Cell , vol.86 , pp. 71-82
    • Schedl, A.1    Ross, A.2    Lee, M.3    EngelKamp, D.4    Rashbass, P.5    van Heyningen, V.6    Hastie, N.D.7
  • 46
    • 34247511981 scopus 로고    scopus 로고
    • p63 is essential for proliferative potential of stem cells in stratified epithelia
    • Senoo M, Pinto F, Crum CP, McKeon F. 2007. p63 is essential for proliferative potential of stem cells in stratified epithelia. Cell 129:523-536.
    • (2007) Cell , vol.129 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3    McKeon, F.4
  • 47
    • 43449137535 scopus 로고
    • Ocular therapeutics in general practice
    • Shaw HA. 1960. Ocular therapeutics in general practice. Lancet 80:359-365.
    • (1960) Lancet , vol.80 , pp. 359-365
    • Shaw, H.A.1
  • 48
    • 0027336491 scopus 로고    scopus 로고
    • Sherr CJ. 1993. Mammalian G1 genes. Cell 73:1059-1065.
    • Sherr CJ. 1993. Mammalian G1 genes. Cell 73:1059-1065.
  • 49
    • 0034212574 scopus 로고    scopus 로고
    • Pax-6 expression and activity in the reepithelialising cornea control activity of the transcriptional promoter for matrix metalloproteinase gelatinase B
    • Sivak JM, Mohan R, Rinehart WB, Xu PX, Maas RL, Fine ME. 2002. Pax-6 expression and activity in the reepithelialising cornea control activity of the transcriptional promoter for matrix metalloproteinase gelatinase B. Dev Biol 222:41-54.
    • (2002) Dev Biol , vol.222 , pp. 41-54
    • Sivak, J.M.1    Mohan, R.2    Rinehart, W.B.3    Xu, P.X.4    Maas, R.L.5    Fine, M.E.6
  • 50
    • 0345732635 scopus 로고    scopus 로고
    • Transcription factors Pax6 and AP-2alpha interact to coordinate corneal epithelial repair by controlling expression of matrix metalloproteinase Gelatinase B
    • Sivak JM, West-Mays JA, Yee A, Williams T, Fini ME. 2004. Transcription factors Pax6 and AP-2alpha interact to coordinate corneal epithelial repair by controlling expression of matrix metalloproteinase Gelatinase B. Mol Cell Biol 24:245-257.
    • (2004) Mol Cell Biol , vol.24 , pp. 245-257
    • Sivak, J.M.1    West-Mays, J.A.2    Yee, A.3    Williams, T.4    Fini, M.E.5
  • 51
    • 0035281572 scopus 로고    scopus 로고
    • A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens
    • Thut CJ, Rountree RB, Hwa M, Kingsley DM. 2001. A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol 231:63-76.
    • (2001) Dev Biol , vol.231 , pp. 63-76
    • Thut, C.J.1    Rountree, R.B.2    Hwa, M.3    Kingsley, D.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.