Transcriptional regulation of the human PNRC promoter by NFY in HepG2 cells

Journal of Biochemistry

Volumn 143, Issue 5, 2008, Pages 675-683

  Zhang, Yan ^a   Chen, Bin ^a   Li, Yuping ^a   Chen, Jian ^a   Lou, Guiyu ^a   Chen, Min ^a   Zhou, Dujin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

NFY; Nuclear receptor co activator; PNRC; Promoter analysis; Transcriptional regulation

Indexed keywords

NUCLEAR FACTOR Y; PROLINE RICH NUCLEAR RECEPTOR COACTIVATOR PROTEIN; PROTEIN;

ARTICLE; BINDING SITE; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA FLANKING REGION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MUTAGENESIS; NUCLEOTIDE SEQUENCE; TRANSCRIPTION REGULATION;

5' FLANKING REGION; BASE SEQUENCE; BINDING SITES; CCAAT-BINDING FACTOR; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

BOVINAE;

EID: 43449102488     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvn019     Document Type: Article

References (25)

1. Chambon, P. (2005) The nuclear receptor superfamily: a personal retrospect on the first two decades. Mol. Endocrinol. 19, 1418-1428
2. Evans, R.M. (2005) The nuclear receptor superfamily: a rosetta stone for physiology. Mol. Endocrinol. 19, 1429-1438
3. Robyr, D., Wolffe, A.P., and Wahli, W. (2000) Nuclear hormone receptor coregulators in action: diversity for shared tasks. Mol. Endocrinol. 14, 329-347
4. Smith, C.L. and O'Malley, B.W. (2004) Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocrinol. Rev. 25, 45-71
5. Xu, J. and Li, Q. (2003) Review of the in vivo functions of the p160 steroid receptor coactivator family. Mol. Endocrinol. 17, 1681-1692
6. Zhou, D., Quach, K.M., Yang, C., Lee, S.Y., Pohajdak, B., and Chen, S. (2000) PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors including orphan receptors SF1 (steroidogenic factor 1) and ERRa1 (estrogen related receptor a-1). Mol. Endocrinol. 14, 986-998
7. Zhou, D. and Chen, S. (2001) PNRC2 is a 16 kDa coactivator that interacts with nuclear receptors through an SH3-binding motif. Nucleic Acid Res. 29, 3939-3948
8. Albers, M., Kranz, H., Kober, I., Kaiser, C., Klink, M., Suckow, J., Kern, R., and Koegl, M. (2005) Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Mol. Cell Proteomics. 4, 205-213
9. Zhou, D., Ye, J.J., Li, Y., Lui, K., and Chen, S. (2006) The molecular basis of the interaction between the proline-rich SH3-binding motif of PNRC and estrogen receptor alpha. Nucleic Acids Res. 34, 5974-5986
10. Zhou, D., Chen, B., Ye, J.J., and Chen, S. (2004) A novel crosstalk mechanism between nuclear receptor-mediated and growth factor/Ras-mediated pathways through PNRC-Grb2 interaction. Oncogene 23, 5394-5404
11. Zhou, D., Zhong, S., Ye, J.J., Qauch, K.M., Johnson, D.L., and Chen, S. (2007) PNRC is a unique nuclear receptor coactivator that stimulates RNA polymerase III-dependent transcription. J. Mol. Signal. 2, 5
12. Kanai, Y., Ushijima, S., Saito, Y., Nakanishi, Y., Sakamoto, M., and Hirohashi, S. (2001) MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers. J. Cancer Res. Clin. Oncol. 127, 697-706
13. Zhou, D., Clark, P., Wang, F., and Chen, S. (1996) Identification of a promoter that controls aromatase expression in human breast cancer and adipose stromal cells. J. Biol. Chem. 271, 15194-15202
14. Mantovani, R. (1999) The molecular biology of the CCAATbinding factor NFY. Gene 18, 15-27
15. Marziali, G., Perrotti, E., Ilari, R., Coccia, E.M., Mantovani, R., Testa, U., and Battistini, A. (1999) The activity of the CCAAT-box binding factor NF-Y is modulated through the regulated expression of its A subunit during monocyte to macrophage differentiation: regulation of tissue-specific genes through a ubiquitous transcription factor. Blood. 93, 519-526
16. Reith, W., Siegrist, C.A., Burand, B., Barras, E., and Mach, B. (1994) Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NFY. Proc. Natl. Acad. Sci. USA 91, 554-558
17. Nicolas, M., Noe, V., and Ciudad, C.J. (2003) Transcriptional regulation of the human Sp1 gene promoter by the specificity protein (Sp) family members nuclear factor Y (NFY) and E2F. Biochem. J. 371, 265-275
18. Radomska, H.S., Satterthwaite, A.B., Taranenko, N., Narravula, S., Krause, D.S., and Tenen, D.G. (1999) A nuclear factor Y (NFY) site positively regulates the human CD34 stem cell gene. Blood 94, 3772-3780
19. Cagen, L.M., Deng, X., Wilcox, H.G., Park, E.A., Raghow, R., and Elam, M.B. (2005) Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NFY cis-acting elements. Biochem. J. 385, 207-216
20. Huang, D.Y., Kuo, Y.Y., Lai, J.S., Suzuki, Y., Sugano, S., and Chang, Z.F. (2004) GATA-1 and NFY cooperate to mediate erythroid-specific transcription of Gfi-1B gene. Nucleic Acid Res. 32, 3935-3946
21. Caretti, G., Salsi, V., Vecchi, C., Imbriano, C., and Mantovani, R. (2003) Dynamic recruitment of NFY and histone acetyltransferases on cellcycle promoters. J. Biol. Chem. 278, 30435-30440
22. Li, Q., Herrler, M., Landsberger, N., Kaludov, N., Ogryzko, V.V., Nakatani, Y., and Wolffe, A.P. (1998) Xenopus NF-Ypre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivo. EMBO J. 17, 6300-6315
23. Frontini, M., Imbriano, C., diSilvio, A., Bell, B., Bogni, A., Romier, C., Moras, D., Tora, L., Davidson, I., and Mantovani. (2002) NF-Y recruitment of TFIID, multiple interactions with histone fold TAF(II)s. J. Biol. Chem. 277, 5841-5848
24. Coustry, F., Sinha, S., Maity, S.N., and Crombrugghe, B. (1998) The two activation domains of the CCAAT-binding factor CBF interact with the dTAFII110 component of the Drosophila TFIID complex. Biochem. J. 331(Pt 1), 291-297
25. Peng, Y. and Jahroudi, N. (2003) The NFY transcription factor inhibits von Willebrand factor promoter activation in non-endothelial cells through recruitment of histone deacetylases. J. Biol. Chem. 278, 8385-8394