Caspase inhibition of platelet activation

Blood Coagulation and Fibrinolysis

Volumn 19, Issue 4, 2008, Pages 305-309

  Cohen, Zoë ^a,c   Davis Gorman, Grace ^b   McDonagh, Paul F ^b,c   Ritter, Leslie ^a,c  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

Caspase; Diabetes; Platelet

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; PHOSPHATE BUFFERED SALINE; PHOSPHATIDYLSERINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME MECHANISM; IN VIVO STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PLATELET MICROPARTICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; ZUCKER DIABETIC FATTY RAT;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; BLOOD PLATELETS; CASPASES; DIABETES MELLITUS, TYPE 2; PLATELET ACTIVATION; PLATELET AGGREGATION; RATS; RATS, ZUCKER;

EID: 43449097875     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e3283001cf5     Document Type: Article

References (34)

1. Shcherbina A, Remold-O'Donnell E. Role of caspase in a subset of human platelet activation responses. Blood 1999; 93:4222-4231.
2. Li J, Xia Y, Bertino AM, Coburn JP, Kuter DJ. The mechanism of apoptosis in human platelets during storage. Transfusion 2000; 40:1320-1329.
3. Salvesen GS, Dixit VM. Caspases: intracellular signaling by proteolysis. Cell 1997; 91:443-446.
4. Wolf BB, Goldstein JC, Stennicke HR, Beere H, Amarante-Mendes GP, Salvesen GS, Green DR. Calpain functions in a caspase-independent manner to promote apoptosis-like events during platelet activation. Blood 1999; 94:1683-1692.
5. Cohen Z, Gonzales RF, Davis-Gorman G, McDonagh PF. Thrombin activity and platelet microparticle formation are increased in type 2 diabetic platelets: a potential correlation with caspase activation. Thromb Res 2002; 107:217-221.
6. Leytin V, Freedman J. Platelet apoptosis in stored platelet concentrates and other models. Transfus Apher Sci 2003; 28:285-295.
7. Piguet PF, Kan CD, Vesin C. Thrombocytopenia in an animal model of malaria is associated with an increased caspase-mediated death of thrombocytes. Apoptosis 2002; 7:91-98.
8. Piguet PF, Vesin C, Kan CD. Activation of platelet caspases by TNF and its consequences for kinetics. Cytokine 2002; 18:222-230.
9. Pereira J, Soto M, Palomo I, Ocqueteau M, Coetzee L-M, Astudillo S, et al. Platelet aging in vivo is associated with activation of apoptotic pathways: studies in a model of suppressed thrombopoiesis in dogs. Thromb Haemost 2002; 87:905-909.
10. Perrotta PL, Perrotta CL, Snyder EL. Apoptotic activity in stored human platelets. Transfusion 2003; 43:526-535.
11. Maurer-Spurej E, Devine DD. Platelet aggregation is not initiated by platelet shape change. Lab Invest 2001; 81:1517-1525.
12. Cohen Z, Wilson J, Ritter L, McDonagh P. Caspase inhibition decreases both platelet phosphatidylserine exposure and aggregation. Thromb Res 2004; 113:387-393.
13. Cohen JJ. Apoptosis: mechanism of life and death in the immune system. J Allergy Clin Immunol 1999; 103:548-554.
14. McDonagh PF. Platelets reduce coronary microvascular permeability to macromolecules. Am J Physiol 1986; 251:H581-H587.
15. Reynolds JM, McDonagh PF. Platelets do not modulate leukocyte-mediated coronary microvascular damage during early reperfusion. Am J Physiol 1994; 266:H171-H181.
16. Weerheim AM, Kolb AM, Sturk A, Nieuwland R. Phospholipid composition of cell-derived microparticles determined by one-dimensional high-performance thin-layer chromatography. Anal Biochem 2002; 302:191-198.
17. Tzima E, Trotter PJ, Orchard MA, Walker JH. Annexin V binds to the actin-based cytoskeleton at the plasma membrane of activated platelets. Exp Cell Res 1999; 251:185-193.
18. Hammill AK, Uhr JW, Scheuermann RH. Annexin V staining due to loss of membrane asymmetry can be reversible and precede commitment to apoptotic death. Exp Cell Res 1999; 251:16-21.
19. Murer EH, Gyda MA, Martinez NJ. Insulin increases the aggregation response of human platelets to ADP. Thromb Res 1994; 73:69-74.
20. Walkowiak B, Kesy A, Michalec L. Microplate reader: a convenient tool in studies of blood coagulation. Thromb Res 1997; 87:95-103.
21. Wallén NH, Ladjevardi M, Albert J, Bröijersén A. Influence of different anticoagulants on platelet aggregation in whole blood; a comparison between citrate, low molecular mass heparin and hirudin. Thromb Res 1997; 87:151-157.
22. Kim HK, Song KS, Lee ES, Lee YL, Park YS, Lee KR, Lee SN. Optimized flow cytometric assay for the measurement of platelet microparticles in plasma: preanalytic and analytic considerations. Blood Coagul Fibrinolysis 2002; 13:393-397.
23. Hokama JY, Susa NJ, Seaver NA, McDonagh PF. Platelet-activating factor induced expression of CD11b in diabetic rats. Microcirculation 1996; 3:90.
24. Hokama JY, Mullarkey PJ, Logan JJ, Cimetta AD, Leprince P, Goldman S, et al. Platelet-leukocyte interactions are increased in patients with type II diabetes. FASEB J 1999; 13:A660.
25. Born GVR. Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature 1962; 4832:927-929.
26. Dwyer SD, Meyers KM. Anesthetics and anticoagulants used in the preparation of rat platelet-rich-plasma alter rat platelet aggregation. Thromb Res 1986; 42:139-151.
27. Dwyer SD, Meyers KM. Rat platelet aggregation: strain and stock variations. Thromb Res 1986; 42:49-53.
28. Marciniak SJJ, Mascelli MA, Furman MI, Michelson AD, Jakubowski JA, Jordan RE, et al. An additional mechanism of action of abciximab: dispersal of newly formed platelet aggregates. Thromb Haemost 2002; 87:1020-1025.
29. Dowdy S, Wearden S. Statistics for research. New York: John Wiley & Sons; 1983. pp. 1-537.
30. Katopodis JN, Kolodny L, Jy W, Horstman LL, De Marchena EJ, Tao JG, et al. Platelet microparticles and calcium homeostasis in acute coronary ischemias. Am J Hematol 1997; 54:95-101.
31. Radziwon P, Boczkowska-Radziwon B, Schenk JF, Wojtukiewicz MZ, Kloczko J,Giedrojc J, Breddin HK. Platelet activation and its role in thrombin generation in platelet-induced thrombin generation time. Thromb Res 2000; 100:419-426.
32. Berino AM, Qi XQ, Li J, Xia Y, Kuter DJ. Apoptotic markers are increased in platelets stored at 37°C. Transfusion 2003; 43:857-866.
33. 1- and Bax-α-mediated regulation of apoptosis of human neutrophils via caspase-3. Blood 1999; 93:3106-3115.
34. Piguet PF, Vesin C. Modulation of platelet caspases and life-span by antiplatelet antibodies in mice. Eur J Haematol 2002; 68:253-261.