Site-directed mutagenesis provides insight into racemization and transamination of alanine catalyzed by Treponema denticola cystalysin

Journal of Biological Chemistry

Volumn 279, Issue 35, 2004, Pages 36898-36905

  Cellini, Barbara ^a   Bertoldi, Mariarita ^a   Paiardini, Alessandro ^b   D'Aguanno, Simona ^b   Voltattorni, Carla Borri ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSTS; DATA REDUCTION; ENZYMES; MUTAGENESIS;

RACEMASE ACTIVITY; TRANSAMINATION;

BIOCHEMISTRY;

ALANINE; ALANINE DEHYDROGENASE; AMINO ACID; AMINOTRANSFERASE; BACTERIAL ENZYME; CYSTALYSIN; DOUBLE STRANDED DNA; LACTATE DEHYDROGENASE; LYASE; LYSINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAMINE PHOSPHATE; PYRUVIC ACID; RACEMASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TYROSINE; UNCLASSIFIED DRUG;

ABSORPTION SPECTROPHOTOMETRY; ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME ASSAY; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RACEMIZATION; SITE DIRECTED MUTAGENESIS; TRANSAMINATION; TREPONEMA; TREPONEMA DENTICOLA;

ALANINE; BINDING SITES; CIRCULAR DICHROISM; CYSTATHIONINE GAMMA-LYASE; ESCHERICHIA COLI; KINETICS; LYSINE; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTONS; SPECTROPHOTOMETRY; TREPONEMA; TYROSINE; WATER;

BACTERIA (MICROORGANISMS); TREPONEMA; TREPONEMA DENTICOLA;

EID: 4344706396     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M404449200     Document Type: Article

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