Genetic risk of knee osteoarthritis: A sibling study

Annals of the Rheumatic Diseases

Volumn 63, Issue 9, 2004, Pages 1022-1027

  Neame, R L ^a   Muir, K ^b   Doherty, S ^a   Doherty, M ^a  

^a NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^b QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; FEMALE; GENETIC RISK; HERITABILITY; HUMAN; KNEE OSTEOARTHRITIS; KNEE PAIN; KNEE RADIOGRAPHY; MAJOR CLINICAL STUDY; MALE; PATELLOFEMORAL JOINT; PREVALENCE; PRIORITY JOURNAL; SIBLING; TOTAL KNEE REPLACEMENT; UNITED KINGDOM;

ADULT; AGE DISTRIBUTION; AGED; ENGLAND; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; ODDS RATIO; OSTEOARTHRITIS, KNEE; PREVALENCE; REPRODUCIBILITY OF RESULTS; RISK FACTORS; SEX DISTRIBUTION;

EID: 4344697342     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2003.014498     Document Type: Article

References (21)

1. Felsan DT, Lawrence RC, Dieppe PA, Hirsch R, Helmick CG. Osteoarthritis: new insights. Part 1. The disease and its risk factors. Ann Intern Med 2000;133:635-6.
2. Peat G, McCarney R, Croft P. Knee pain and Osteoarthritis in older adults: a review of the community burden and current use of primary health care. Ann Rheum Dis 2001;60:91-7.
3. Spector TD, Cicuttini F, Baker J, Loughlin J, Hart DJ. Genetic influences on osteoarthritis in women: a twin study. BMJ 1996;312:940-3.
4. Manek NJ, Hart D, Spector TD, MacGregor AJ. The association of body mass index and osteoarthritis of the knee joint. Arthritis Rheum 2003;48:1024-9.
5. Chitnavis J, Sinsheimer JS, Clipsham K, Loughlin J, Sykes B, Burge PD, et al. Genetic influences in end-stage osteoarthritis. Sibling risks of hip and knee replacement for idiopathic osteoarthritis. J Bone Joint Surg Br 1997;79:660-4.
6. Hirsch R, Lethbridge-Ceiku M, Hanson R, Scott WW, Reichle R, Plato CC, et al. Familial aggregation of osteoarthritis. Arthritis Rheum 1998;41:1227-32.
7. Bijkerk C, Houwing-Duistermaat JJ, Valkenburg HA, Meulenbelt I, Hofman A, Breedveld FC, et al. Heritabilities of radiologic osteoarthritis in peripheral joints and of disc degeneration of the spine. Arthritis Rheum 1999;42:1729-35.
8. O'Reilly SC, Muir KR, Doherty M. Screening for pain in knee osteoarthritis: which question? Ann Rheum Dis 1996;55:931-3.
9. Thomas KS, Muir KR, Doherty M, Jones AC, O'Reilly SC, Bassey EJ. Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trial. BMJ 2002;325:752-5.
10. Dieppe PA. Recommended methodology for assessing the progression of osteoarthritis of the hip and knee joints. Osteoarthritis Cartilage 1995;3:73-7.
11. Laurin CA, Dussault R, Levesque HP. The tangential x-ray investigation of the patellofemoral joint: x-ray technique, diagnostic criteria and their interpretation. Clin Orthop Relat Res 1979;144:16-26.
12. Kellgren JH, Lawrence JS. The epidemiology of chronic rheumatism. Atlas of standard radiographs of arthritis. Vol 2. Oxford: Blackwell Scientific, 1963.
13. Nagaosa Y, Mateus M, Hassan B, Lanyon P, Doherty M. Development of a logically devised line drawing atlas for grading of knee osteoarthritis. Ann Rheum Dis 2000;59:587-95.
14. Cohen J. A coefficient of agreement for nominal scales. Educ Psychol Meas 1960;20:37-46.
15. Statistics data analysis for windows. Version 6. Texas, USA: STATA Corporation.
16. SPSS For Windows 10.1. SPSS Inc. Illinois: Chicago, 60606, USA.
17. Falconer DS. Introduction to quantitative genetics, 3rd ed. Harlow: Longman Scientific and Technical, 1989.
18. 1991 Census. County Report: Nottinghamshire (Part 1). London: HMSO, 1992.
19. Lanyon P, Muir K, Doherty S, Doherty M. Assessment of a genetic contribution to osteoarthritis of the hip: sibling study. BMJ 2000;321:1179-83.
20. Willemsen G, Vink JM, Boomsma DI. Assortative mating may explain spouses' risk of same disease. BMJ 2003;326:396.
21. Cooper C, McAlindon T, Snow S, Vines K, Young P, Kirwan J, Dieppe P. Mechanical and constitutional risk factors for symptomatic knee osteoarthritis: differences between medial tibiofemoral and patellofemoral disease. J Rheumatol 1994;21:307-13.