Influence of a lipophilic thermal lubricant on the processing conditions and drug release properties of chlorpheniramine maleate tablets prepared by hot-melt extrusion

Journal of Drug Delivery Science and Technology

Volumn 14, Issue 4, 2004, Pages 313-318

  Zhu, Y ^a   Shah, N H ^b   Malick, A W ^b   Infeld, M H ^b   McGinity, J W ^c  

^a Kos Pharmaceuticals Inc   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Controlled release; Eudragit RS PO; Glyceryl monostearate; Hot melt extrusion; Melt viscosity; Processibility

Indexed keywords

CHLORPHENIRAMINE MALEATE; CITRIC ACID TRIETHYL ESTER; EUDRAGIT; EUDRAGIT RS PO; GLYCEROL STEARATE; LUBRICATING AGENT; POLYACRYLIC ACID;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG RELEASE; GLASS TRANSITION TEMPERATURE; HOT MELT EXTRUSION; LIPOPHILICITY; MELTING POINT; MISCIBILITY; POWDER; SCANNING ELECTRON MICROSCOPY; TABLET MANUFACTURE; THERMOGRAVIMETRY; THERMOSTABILITY; TORQUE; VISCOSITY; X RAY DIFFRACTION;

EID: 4344693923     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1773-2247(04)50053-9     Document Type: Article

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