A mixture of isothiocyanates induces cyclin B1- and p53-mediated cell-cycle arrest and apoptosis of human T lymphoblastoid cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 554, Issue 1-2, 2004, Pages 205-214

  Fimognari, C ^a   Nusse M ^b   Berti, F ^a   Iori, R ^c   Cantelli Forti, G ^a   Hrelia, P ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b GSF Flow Cytometry Group   (Italy)

^c ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

Author keywords

4 (methylthio)butylisothiocyanate; Apoptosis; bax; CDK; Cell cycle; Cyclin B1; cyclin dependent kinase; GER; glucoerucin; glucoraphanin; GRA; Isothiocyanates; MTBITC; p53

Indexed keywords

CYCLIN B1; GLUCOERUCIN; GLUCOIBERIN; GLUCORAPHANIN; GLUCOSINOLATE; ISOTHIOCYANIC ACID; PROTEIN BAX; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHOBLASTOID CELL; MITOSIS INHIBITION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLIN B; FLOW CYTOMETRY; GLUCOSINOLATES; HUMANS; ISOTHIOCYANATES; JURKAT CELLS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 4344692547     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2004.04.009     Document Type: Article

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