Phase II clinical trial of homemade human rh-endostatin in the treatment of patients with stage III B-IV non-small cell lung cancer

Chinese Journal of Lung Cancer

Volumn 7, Issue 4, 2004, Pages 325-328

  Shi, Heling ^a   Xu, Liyan ^a   Liu, Zhe ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Clinical trial; Homemade human rh endostatin; Non small cell lung cancer

Indexed keywords

CISPLATIN; ENDOSTATIN; MITOMYCIN C; NAVELBINE; NITROSOUREA DERIVATIVE; YH 16;

ALOPECIA; ANEMIA; ARTICLE; BLOOD TOXICITY; CANCER GROWTH; CANCER STAGING; CLINICAL ARTICLE; CLINICAL TRIAL; CONSTIPATION; DRUG EFFICACY; DRUG SAFETY; FATIGUE; HEMATURIA; HUMAN; INFECTION; LEUKOPENIA; LUNG NON SMALL CELL CANCER; NAUSEA; NEUTROPENIA; PAIN; PHASE 2 CLINICAL TRIAL; PROTEINURIA; QUALITY OF LIFE; THROMBOCYTOPENIA; VOMITING;

EID: 4344684052     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. O'Reilly MS, Holmgren L, Shing Y, et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell, 1994, 79(2): 315-328.
2. O'Reilly MS, Boehm T, Shing Y, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell. 1997, 88(2): 277-285.
3. Liu JQ, Li ZY, Chen LS, et al. An experimental study on inhibiting growth and metastasis of mouse melanoma by engineering endostatin. J Cell Mol Immunol, 2001, 17(1): 63-64.
4. Su LH, Zhou L, Zhu Y, et al. Recombinant human vascular endostatin inhibits growth of tumors in nude mice. Shandong Journal of Biomedical Engineering, 2002, 2(1): 34-35.