Asymmetric synthesis of (R)-S-(1,2,4-triazol-3-yl)cysteines by nucleophilic addition of triazolethiols to a Ni II complex with a chiral dehydroalanine Schiff base

Russian Chemical Bulletin

Volumn 53, Issue 4, 2004, Pages 932-935

  Saghiyan, A S ^a   Geolchanyan, A V ^a   Manasyan, L L ^a   Mkrtchyan, G M ^a   Martirosyan, N R ^a   Dadayan, S A ^a   Kochickyan, T V ^a   Harutyunyan, V S ^a   Avetisyan, A A ^a   Tararov, V I ^b   Maleev, V I ^b   Belokon', Yu N ^b  

^a YEREVAN STATE UNIVERSITY   (Armenia)

^b A N NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS   (Russian Federation)

Author keywords

asymmetric synthesis; dehydroalanine; diastereoselectivity; enantiomeric analysis; enantiomeric purity; triazolethiols

Indexed keywords

CYSTEINE DERIVATIVE; DEHYDROALANINE; NICKEL COMPLEX; S (4 ALLYL 5 PROPYL 1,2,4 TRIAZOL 3 YL)CYSTEINE; S (4 PHENYL 5 PROPYL 1,2,4 TRIAZOL 3 YL)CYSTEINE; S [4 ALLYL 5 (2 CHLOROPHENYL) 1,2,4 TRIAZOL 3 YL]CYSTEINE; S [4 ALLYL 5 (2 METHOXYPHENYL) 1,2,4 TRIAZOL 3 YL]CYSTEINE; S [4 ALLYL 5 (3 HYDROXY 4 ISOPENTYLOXYBUTYL) 1,2,4 TRIAZOL 3 YL]CYSTEINE; S [4 ALLYL 5 (3 HYDROXYOCTYL) 1,2,4 TRIAZOL 3 YL]CYSTEINE; S [4 ALLYL 5 (3 HYDROXYPROPYL) 1,2,4 TRIAZOL 3 YL]CYSTEINE; S [5 (3 HYDROXY 4 ISOPENTYLOXYBUTYL) 4 PHENYL 1,2,4 TRIAZOL 3 YL]CYSTEINE; S [5 (3 HYDROXYPROPYL) 4 PHENYL 1,2,4 TRIAZOL 3 YL]CYSTEINE; SCHIFF BASE; THIOL DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL BOND; CHIRALITY; DRUG SYNTHESIS; STEREOCHEMISTRY; SUBSTITUTION REACTION; THERMODYNAMICS;

EID: 4344679067     PISSN: 10665285     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:RUCB.0000037866.13065.c7     Document Type: Article

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