메뉴 건너뛰기




Volumn 18, Issue 3-6, 2004, Pages 307-317

Perospirone hydrochloride: The novel atypical antipsychotic agent with high affinities for 5-HT2, D2 and 5-HT1A receptors

Author keywords

5 HT1A receptors; 5 HT2 receptors; Antipsychotic agents; D2 receptors; Extrapyramidal side effects; Perospirone

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; CLOZAPINE; DESIPRAMINE; DIAZEPAM; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; HALOPERIDOL; IMIPRAMINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; OLANZAPINE; PEROSPIRONE; RISPERIDONE; SEROTONIN 1A RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN ANTAGONIST;

EID: 4344663852     PISSN: 01688561     EISSN: None     Source Type: Journal    
DOI: 10.1163/1569391041501906     Document Type: Article
Times cited : (12)

References (27)
  • 1
    • 0030062260 scopus 로고    scopus 로고
    • Radioreceptor binding profile of the atypical antipsychotic olanzapine
    • Brymaster, F. P., Calligara, D. O., Falcone, J. F., et al. (1996). Radioreceptor binding profile of the atypical antipsychotic olanzapine, Neuropsychopharmacology 14, 87-96.
    • (1996) Neuropsychopharmacology , vol.14 , pp. 87-96
    • Bymaster, F.P.1    Calligara, D.O.2    Falcone, J.F.3
  • 2
    • 0023634681 scopus 로고
    • The paw test: A behavioural paradigm for differentiating between classical and atypical neuroleptic drugs
    • Ellenbroek, B. A., Peeters, B. W., Honig, W. M., et al. (1987). The paw test: a behavioural paradigm for differentiating between classical and atypical neuroleptic drugs, Psychopharmacology (Berlin) 93, 343-348.
    • (1987) Psychopharmacology (Berlin) , vol.93 , pp. 343-348
    • Ellenbroek, B.A.1    Peeters, B.W.2    Honig, W.M.3
  • 4
    • 0029995536 scopus 로고    scopus 로고
    • Contrasting effects of SM-9018, a potential atypical antipsychotic, and haloperidol on c-fos mRNA expression in the rat striatum
    • Ishibashi, T., Ikeda, K., Ishida, K., et al. (1996). Contrasting effects of SM-9018, a potential atypical antipsychotic, and haloperidol on c-fos mRNA expression in the rat striatum, Eur. J. Pharmacol. 303, 247-251.
    • (1996) Eur. J. Pharmacol. , vol.303 , pp. 247-251
    • Ishibashi, T.1    Ikeda, K.2    Ishida, K.3
  • 6
    • 0029826027 scopus 로고    scopus 로고
    • Effects of perospirone (SM-9018), a novel serotonin-2 and dopamine-2 receptor antagonist, and other antipsychotics in the conditioned fear stress-induced freezing behavior model in rats
    • Ishida-Tokuda, K., Ohno, Y., Sakamoto, H., et al. (1996). Effects of perospirone (SM-9018), a novel serotonin-2 and dopamine-2 receptor antagonist, and other antipsychotics in the conditioned fear stress-induced freezing behavior model in rats, Jpn. J. Pharmacol. 72, 119-126.
    • (1996) Jpn. J. Pharmacol. , vol.72 , pp. 119-126
    • Ishida-Tokuda, K.1    Ohno, Y.2    Sakamoto, H.3
  • 8
    • 0025615126 scopus 로고
    • Binding profile of SM-9018, a novel antipsychotic candidate
    • Kato, T., Hirose, A., Ohno, Y., et al. (1990). Binding profile of SM-9018, a novel antipsychotic candidate, Jpn. J. Pharmacol. 54, 478-481.
    • (1990) Jpn. J. Pharmacol. , vol.54 , pp. 478-481
    • Kato, T.1    Hirose, A.2    Ohno, Y.3
  • 9
    • 0026562188 scopus 로고
    • In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone
    • Leysen, J. E., Janssen, P. M. F., Gommeren, W., et al. (1992). In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone, Mol. Pharmacol. 41, 494-508.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 494-508
    • Leysen, J.E.1    Janssen, P.M.F.2    Gommeren, W.3
  • 10
    • 0027234566 scopus 로고
    • Effects of SM-9018, a potential atypical neuroleptic, on the central monoaminergic system in rats
    • Maruoka, Y., Ohno, Y., Kato, T., et al. (1993). Effects of SM-9018, a potential atypical neuroleptic, on the central monoaminergic system in rats, Jpn. J. Pharmacol. 62, 419-422.
    • (1993) Jpn. J. Pharmacol. , vol.62 , pp. 419-422
    • Maruoka, Y.1    Ohno, Y.2    Kato, T.3
  • 11
    • 0026357347 scopus 로고
    • Effects of antipsychotic drugs on serotonin receptors
    • Meltzer, H. Y. and Nash, J. F. (1991). Effects of antipsychotic drugs on serotonin receptors, Pharmacol. Rev. 43, 587-604.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 587-604
    • Meltzer, H.Y.1    Nash, J.F.2
  • 13
    • 0001013924 scopus 로고    scopus 로고
    • Clinical evaluation of a new antipsychotic, perospirone HCl, on schizophrenia - A comparative double-blind study with haloperidol
    • Murasaki, M., Koyama, T., Machiyama, Y., et al. (1997). Clinical evaluation of a new antipsychotic, perospirone HCl, on schizophrenia - A comparative double-blind study with haloperidol, Clin. Eval. 24, 159-205.
    • (1997) Clin. Eval. , vol.24 , pp. 159-205
    • Murasaki, M.1    Koyama, T.2    Machiyama, Y.3
  • 14
    • 0033828218 scopus 로고    scopus 로고
    • Repeated phencyclidine treatment induces negative symptom-like behavior in forced swimming test in mice: Imbalance of prefrontal serotonergic and dopaminergic functions
    • Noda, Y., Kamei, H., Mamiya, T., et al. (2000). Repeated phencyclidine treatment induces negative symptom-like behavior in forced swimming test in mice: imbalance of prefrontal serotonergic and doparninergic functions, Neuropsychopharmacology 23, 375-387.
    • (2000) Neuropsychopharmacology , vol.23 , pp. 375-387
    • Noda, Y.1    Kamei, H.2    Mamiya, T.3
  • 15
    • 4344705143 scopus 로고    scopus 로고
    • Pharmacological characteristics of the new atypical antipsychotic agents, serotonin-dopamine antagonists (SDA)
    • Ohno, Y. (2002). Pharmacological characteristics of the new atypical antipsychotic agents, serotonin-dopamine antagonists (SDA), Jpn. J. Clin. Psychopharmacol. 5, 147-153.
    • (2002) Jpn. J. Clin. Psychopharmacol. , vol.5 , pp. 147-153
    • Ohno, Y.1
  • 21
    • 0028135046 scopus 로고
    • Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity
    • Robertson, G. S., Matsumura, H. and Fibiger, H. C. (1994). Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity, J. Pharmacol. Exp. Ther. 271, 1058-1066.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 1058-1066
    • Robertson, G.S.1    Matsumura, H.2    Fibiger, H.C.3
  • 22
    • 0031824953 scopus 로고    scopus 로고
    • Anxiolytic-like effects of perospirone, a novel serotonin-2 and dopamine-2 antagonist (SDA)-type antipsychotic agent
    • Sakamoto, H., Matsumoto, K., Ohno, Y., et al. (1998). Anxiolytic-like effects of perospirone, a novel serotonin-2 and dopamine-2 antagonist (SDA)-type antipsychotic agent, Pharmacol. Biochem. Behav. 60, 873-878.
    • (1998) Pharmacol. Biochem. Behav. , vol.60 , pp. 873-878
    • Sakamoto, H.1    Matsumoto, K.2    Ohno, Y.3
  • 23
    • 0025279451 scopus 로고
    • Comparison of chronic administration of haloperidol and the atypical neuroleptics, clozapine and raclopride, in an animal model of tardive dyskinesia
    • See, R. E. and Ellison, G. (1990). Comparison of chronic administration of haloperidol and the atypical neuroleptics, clozapine and raclopride, in an animal model of tardive dyskinesia, Eur. J. Pharmacol. 181, 175-186.
    • (1990) Eur. J. Pharmacol. , vol.181 , pp. 175-186
    • See, R.E.1    Ellison, G.2
  • 26
    • 0345209936 scopus 로고    scopus 로고
    • Studies on central actions of perospirone hydrochloride, a novel antipsychotic agent
    • Tokuda, K., Ohno, Y., Ishibashi, T., et al. (1997). Studies on central actions of perospirone hydrochloride, a novel antipsychotic agent, Clin. Rep. 31, 853-878.
    • (1997) Clin. Rep. , vol.31 , pp. 853-878
    • Tokuda, K.1    Ohno, Y.2    Ishibashi, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.