Multisystem evaluations of the long-term effects of tibolone on postmenopausal monkeys

Maturitas

Volumn 48, Issue SUPPL. 1, 2004, Pages 24-29

  Clarkson, T B ^a   Anthony, M S ^a   Cline, J M ^a   Lees, C J ^a   Ederveen, A G H ^b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b NV ORGANON   (Netherlands)

Author keywords

Conjugated equine oestrogen; Medroxyprogesterone acetate; Tibolone

Indexed keywords

CONJUGATED ESTROGEN; MEDROXYPROGESTERONE ACETATE; TIBOLONE;

ATHEROGENIC DIET; BONE; BREAST; CONFERENCE PAPER; CORONARY ARTERY ATHEROSCLEROSIS; DRUG EFFECT; ENDOMETRIUM; MAMMARY GLAND; MONKEY; NONHUMAN; OVARIECTOMY; POSTMENOPAUSE OSTEOPOROSIS; UTERUS;

EQUIDAE; MACACA FASCICULARIS;

EID: 4344662917     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2004.02.011     Document Type: Conference Paper

References (8)

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3. Crona N., Silfverstolpe G., Samsoie G. A double-blind cross-over study on the effects of Org OD 14 compared to oestradiol valerate and placebo on lipid and carbohydrate metabolism in oophorectomized women. Acta Endocrinol. 102:1983;451-455
4. Clarkson T.B., Anthony M.S., Wagner J.D. A comparison of tibolone and conjugated equine estrogens effects on coronary artery atherosclerosis and bone density of postmenopausal monkeys. J. Clin. Endocrinol. Metab. 86:2001;5396-5404
5. Mikkola T.S., Anthony M.S., Clarkson T.B., St.Clair R.W. Serum cholesterol efflux in postmenopausal monkeys treated with tibolone or conjugated estrogens. Metabolism. 51(4):2002;523-530
6. Lees C.J., Ederveen A.G.H., Clarkson T.B. Tibolone treatment in ovariectomized macaques. J. Bone Miner. Res. 16:2001;5537. (Abstract)
7. Cline J.M., Register T.C., Clarkson T.B. Comparative effects of tibolone and conjugated equine estrogens with and without medroxyprogesterone acetate on the reproductive tract of female cynomolgus monkeys. Menopause. 9:2002;242-252
8. Cline J.M., Register T.C., Clarkson T.B. Effects of tibolone and hormone replacement therapy on the breast of cynomolgus monkeys. Menopause. 9:2002;422-429