Local influence analysis when interfacing toxicokinetic and proportional hazard models

Statistics in Medicine

Volumn 23, Issue 15, 2004, Pages 2399-2412

  Sartori, Nicola ^a   Thomaseth, Karl ^b   Salvan, Alberto ^b  

^a CA' FOSCARI UNIVERSITY OF VENICE   (Italy)

^b CNR   (Italy)

Author keywords

Dioxin; Local influence; Partial likehood; Proportional hazard model; Toxicokinetic models

Indexed keywords

DIOXIN;

ADULT; ARTICLE; CANCER MORTALITY; CHEMICAL CARCINOGENESIS; CHEMICAL INDUSTRY; DOSE RESPONSE; HUMAN; HUMAN TISSUE; INDUSTRIAL WORKER; LUNG CANCER; MAJOR CLINICAL STUDY; NONBIOLOGICAL MODEL; OCCUPATIONAL EXPOSURE; RISK ASSESSMENT; STATISTICAL PARAMETERS; TOXICOKINETICS;

CARCINOGENS; DIOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; ITALY; NEOPLASMS; PROPORTIONAL HAZARDS MODELS;

EID: 4344661974     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/sim.1823     Document Type: Article

References (24)

1. Saltelli A, Chan K, Scott EM. Sensitivity Analysis. Wiley: New York, 2000.
2. Cook DR. Assessment of local influence. Journal of the Royal Statistical Society B 1986; 48(2):133-169.
3. Fingerhut MA, Halperin WE, Marlow DA, Piacitelli LA, Honchar PA, Sweeney MH, Greife AL, Dill PA, Steenland K, Suruda AJ. Cancer mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. New England Journal of Medicine 1991; 324:212-218.
4. Thomaseth K, Salvan A. Estimation of occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin using a minimal physiologic toxicokinetic model. Environmental Health Perspectives 1998; 106:743-753.
5. Salvan A, Thomaseth K, Bortot P, Sartori N. Uncertainty in estimating exposure using a toxicokinetic model: The example of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Annals of the New York Academy of Sciences 1999; 895:125-140.
6. Bortot P, Thomaseth K, Salvan A. Population toxicokinetic analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin using Bayesian techniques. Statistics in Medicine 2002; 21:533-547.
7. Salvan A, Thomaseth K, Bortot P, Sartori N. Use of a toxicokinetic model in the analysis of cancer mortality in relation to estimated absorbed dose of dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD). The Science of the Total Environment 2001; 274:21-35.
8. Suárez Rancel MM, González Sierra MA. Regression diagnostic using local influence: a review. Communication in Statistics - Theory and Methods 2001; 30(5):799-813.
9. Billor N, Loynes RM. Local influence: a new approach. Communication in Statistics - Theory and Methods 1993; 22(6):1595 -1611.
10. Loynes RM. A new measure in local influence. Journal of Statistical Planning and Inference 2001; 92:47-53.
11. Verbeke G, Molenberghs G, Thijs H, Lesaffre E, Kenward MG. Sensitivity analysis for nonrandom dropouts: a local influence approach. Biometrics 2001; 57:7-14.
12. Weissfeld LA. Influence diagnostics for the proportional hazard model. Statistics and Probability Letters 1990; 10:411-417.
13. Barlow WE. Global measure of local influence for proportional hazard models. Biometrics 1997; 53:1157-1162.
14. Pettitt AN, Bin Daud I. Case-weighted measures of influence for proportional hazard models. Applied Statistics 1989; 38(1):51-67.
15. Cain KC, Lange NT. Approximate case influence for the proportional hazards regression model with censored data. Biometrics 1984; 40:493-499.
16. Reid N, Crépeau H. Influence functions for proportional hazard regression. Biometrika 1985; 72(1):1-9.
17. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Polychlorinated Dibenzo-paradioxins and Polychlorinated Dibenzofurans. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol. 69. IARC: Lyon, France, 1997.
18. Steenland K, Piacitelli L, Deddens J, Fingerhut M, Chang LI. Cancer, heart disease, and diabetes in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Journal of the National Cancer Institute 1999; 91:779-786.
19. Steenland K, Deddens J, Piacitelli L. Risk assessment for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on an epidemiologic study. American Journal of Epidemiology 2001; 154:451-458.
20. Knapik JJ, Burse RL, Vogel JA. Height, weight, per cent body fat, and indices of adiposity for young men and women entering the U.S. army. Aviation Space and Environmental Medicine 1983; 54:223-231.
21. ICRP-International Commission on Radiological Protection. The Reference Man. Report No. 23. Pergamon Press: Oxford, 1975.
22. Thomaseth K. PANSYM: a symbolic equation generator for mathematical modelling, analysis and control of metabolic and pharmacokinetic systems. Computer Methods and Programs in Biomedicine 1994; 42(2):99-112.
23. Schall R, Dunne TT. A note on the relationship between parameter collinearity and local influence. Biometrika 1992; 79(2):399-404.
24. Fung WK, Kwan CW. A note on local influence based on normal curvature. Journal of the Royal Statistical Society B 1997; 59(4):839-843.