The albumin controversy

Clinics in Perinatology

Volumn 31, Issue 3, 2004, Pages 475-488

  Uhing, Michael R ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ENDOTOXIN; FIBRINOGEN; IMMUNOGLOBULIN G; SERUM ALBUMIN;

ABDOMINAL AORTA ANEURYSM; ALBUMIN BLOOD LEVEL; BLOOD TRANSFUSION; CAPILLARY PERMEABILITY; CRITICAL ILLNESS; EVALUATION; FLUID THERAPY; GESTATIONAL AGE; GOLGI COMPLEX; HUMAN; HYDROSTATIC PRESSURE; HYPOALBUMINEMIA; HYPOVOLEMIA; LABORATORY TEST; LENGTH OF STAY; LIVER CELL; MOLECULAR WEIGHT; NECROTIZING ENTEROCOLITIS; NUTRITIONAL DEFICIENCY; ONCOTIC PRESSURE; PLASMA OSMOLALITY; PLASMAPHERESIS; POSTOPERATIVE CARE; PREMATURITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; RESPIRATORY TRACT DISEASE; RESUSCITATION; REVIEW; SEPSIS; SURGICAL PATIENT; TISSUE OXYGENATION; WOUND DEHISCENCE;

ALBUMINS; CRITICAL ILLNESS; HUMANS; HYPOALBUMINEMIA; HYPOTENSION; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; RESPIRATION DISORDERS; SEPSIS;

EID: 4344655948     PISSN: 00955108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clp.2004.03.018     Document Type: Review

References (92)

1. Vincent J.L., Dubois M.J., Navickis R.J., Wilkes M.M. Hypoalbuminemia in acute illness: is there a rationale for intervention? A meta-analysis of cohort studies and controlled trials. Ann Surg. 237(3):2003;319-334
2. Gibbs J., Cull W., Henderson W., Daley J., Hur K., Khuri S.F. Preoperative serum albumin level as a predictor of operative mortality and morbidity: results from the National VA Surgical Risk Study. Arch Surg. 134(1):1999;36-42
3. Cochrane Injuries Group Albumin Reviewers Human albumin administration in critically ill patients: systematic review of randomised controlled trials. BMJ. 317(7153):1998;235-240
4. Boldt J. The good, the bad, and the ugly: should we completely banish human albumin from our intensive care units [table of contents]? Anesth Analg. 91(4):2000;887-895
5. Haynes G.R., Navickis R.J., Wilkes M.M. Albumin administration - what is the evidence of clinical benefit? A systematic review of randomized controlled trials. Eur J Anaesthesiol. 20(10):2003;771-793
6. Allison S.P., Lobo D.N. Debate: albumin administration should not be avoided. Crit Care. 4(3):2000;147-150
7. Wilkes M.M., Navickis R.J. Patient survival after human albumin administration. A meta-analysis of randomized, controlled trials. Ann Intern Med. 135(3):2001;149-164
8. Doweiko J.P., Nompleggi D.J. Role of albumin in human physiology and pathophysiology. JPEN J Parenter Enteral Nutr. 15(2):1991;207-211
9. Margarson M.P., Soni N. Serum albumin: touchstone or totem? Anaesthesia. 53(8):1998;789-803
10. Takagi M., Ogata K. Direct evidence for albumin biosynthesis by membrane bound polysomes in rat liver. Biochem Biophys Res Commun. 33(1):1968;55-60
11. Rothschild M.A., Oratz M., Schreiber S.S. Serum albumin. Hepatology. 8(2):1988;385-401
12. Pietrangelo A., Panduro A., Chowdhury J.R., Shafritz D.A. Albumin gene expression is down-regulated by albumin or macromolecule infusion in the rat. J Clin Invest. 89(6):1992;1755-1760
13. Yamauchi A., Fukuhara Y., Yamamoto S., Yano F., Takenaka M., Imai E., et al. Oncotic pressure regulates gene transcriptions of albumin and apolipoprotein B in cultured rat hepatoma cells. Am J Physiol. 263(2 Pt 1):1992;C397-C404
14. Hutson S.M., Stinson-Fisher C., Shiman R., Jefferson L.S. Regulation of albumin synthesis by hormones and amino acids in primary cultures of rat hepatocytes. Am J Physiol. 252(3 Pt 1):1987;E291-E298
15. Bent-Hansen L., Feldt-Rasmussen B., Kverneland A., Deckert T. Transcapillary escape rate and relative metabolic clearance of glycated and non-glycated albumin in type 1 (insulin-dependent) diabetes mellitus. Diabetologia. 30(1):1987;2-4
16. Joles J.A., Rabelink T.J., Braam B., Koomans H.A. Plasma volume regulation: defences against edema formation (with special emphasis on hypoproteinemia). Am J Nephrol. 13(5):1993;399-412
17. Blunt M.C., Nicholson J.P., Park G.R. Serum albumin and colloid osmotic pressure in survivors and nonsurvivors of prolonged critical illness. Anaesthesia. 53(8):1998;755-761
18. Barclay S.A., Bennett D. The direct measurement of plasma colloid osmotic pressure is superior to colloid osmotic pressure derived from albumin or total protein. Intensive Care Med. 13(2):1987;114-118
19. Grundmann R., Heistermann S. Postoperative albumin infusion therapy based on colloid osmotic pressure. A prospectively randomized trial. Arch Surg. 120(8):1985;911-915
20. Bartels C., Hadzik B., Abel M., Roth B., Diefenbach C., De Vive R. The significance of oncometry for infusion therapy during pediatric heart surgery. J Cardiovasc Surg (Torino). 38(3):1997;249-255
21. Guardia J.A., Ortiz-Butcher C., Bourgoignie J.J. Oncotic pressure and edema formation in hypoalbuminemic HIV-infected patients with proteinuria. Am J Kidney Dis. 30(6):1997;822-828
22. Cartlidge P.H., Rutter N. Serum albumin concentrations and oedema in the newborn. Arch Dis Child. 61(7):1986;657-660
23. Buehler B.A. Hereditary disorders of albumin synthesis. Ann Clin Lab Sci. 8(4):1978;283-286
24. Watkins S., Madison J., Galliano M., Minchiotti L., Putnam F.W. Analbuminemia: three cases resulting from different point mutations in the albumin gene. Proc Natl Acad Sci USA. 91(20):1994;9417-9421
25. Elias R.M., Johnston M.G., Hayashi A., Nelson W. Decreased lymphatic pumping after intravenous endotoxin administration in sheep. Am J Physiol. 253(6 Pt 2):1987;H1349-H1357
26. Johnston M.G., Elias R.M., Hayashi A., Nelson W. Role of the lymphatic circulatory system in shock. J Burn Care Rehabil. 8(6):1987;469-474
27. Ballmer P.E. Causes and mechanisms of hypoalbuminaemia. Clin Nutr. 20(3):2001;271-273
28. Reading R.F., Ellis R., Fleetwood A. Plasma albumin and total protein in preterm babies from birth to eight weeks. Early Hum Dev. 22(2):1990;81-87
29. Zlotkin S.H., Casselman C.W. Percentile estimates of reference values for total protein and albumin in sera of premature infants (less than 37 weeks of gestation). Clin Chem. 33(3):1987;411-413
30. Barle H., Gamrin L., Essen P., McNurlan M.A., Garlick P.J., Wernerman J. Growth hormone does not affect albumin synthesis in the critically ill. Intensive Care Med. 27(5):2001;836-843
31. O'Leary M.J., Koll M., Ferguson C.N., Coakley J.H., Hinds C.J., Preedy V.R., et al. Liver albumin synthesis in sepsis in the rat: influence of parenteral nutrition, glutamine, and growth hormone. Clin Sci (Lond). 105(6):2003;691-698
32. Foley E.F., Borlase B.C., Dzik W.H., Bistrian B.R., Benotti P.N. Albumin supplementation in the critically ill. A prospective, randomized trial. Arch Surg. 125(6):1990;739-742
33. Golub R., Sorrento J.J. Jr., Cantu R. Jr., Nierman D.M., Moideen A., Stein H.D. Efficacy of albumin supplementation in the surgical intensive care unit: a prospective, randomized study. Crit Care Med. 22(4):1994;613-619
34. Rubin H., Carlson S., DeMeo M., Ganger D., Craig R.M. Randomized, double-blind study of intravenous human albumin in hypoalbuminemic patients receiving total parenteral nutrition. Crit Care Med. 25(2):1997;249-252
35. Greenhalgh D.G., Housinger T.A., Kagan R.J., Rieman M., James L., Novak S., et al. Maintenance of serum albumin levels in pediatric burn patients: a prospective, randomized trial. J Trauma. 39(1):1995;67-73
36. Lowe R.J., Moss G.S., Jilek J., Levine H.D. Crystalloid vs colloid in the etiology of pulmonary failure after trauma: a randomized trial in man. Surgery. 81(6):1977;676-683
37. Shires G.T. III, Peitzman A.B., Albert S.A., Illner H., Silane M.F., Perry M.O., et al. Response of extravascular lung water to intraoperative fluids. Ann Surg. 197(5):1983;515-519
38. Zetterstrom H. Albumin treatment following major surgery. II. Effects on postoperative lung function and circulatory adaptation. Acta Anaesthesiol Scand. 25(2):1981;133-141
39. Virgilio R.W., Rice C.L., Smith D.E., James D.R., Zarins C.K., Hobelmann C.F., et al. Crystalloid vs. colloid resuscitation: is one better? A randomized clinical study. Surgery. 85(2):1979;129-139
40. Rackow E.C., Weil M.H., Macneil A.R., Makabali C.G., Michaels S. Effects of crystalloid and colloid fluids on extravascular lung water in hypoproteinemic dogs. J Appl Physiol. 62(6):1987;2421-2425
41. Rackow E.C., Astiz M.E., Schumer W., Weil M.H. Lung and muscle water after crystalloid and colloid infusion in septic rats: effect on oxygen delivery and metabolism. J Lab Clin Med. 113(2):1989;184-189
42. Ellman H. Capillary permeability in septic patients. Crit Care Med. 12(8):1984;629-633
43. Fleck A., Raines G., Hawker F., Trotter J., Wallace P.I., Ledingham I.M., et al. Increased vascular permeability: a major cause of hypoalbuminaemia in disease and injury. Lancet. 1(8432):1985;781-784
44. Ballmer P.E., Ochsenbein A.F., Schutz-Hofmann S. Transcapillary escape rate of albumin positively correlates with plasma albumin concentration in acute but not in chronic inflammatory disease. Metabolism. 43(6):1994;697-705
45. Marx G., Cobas Meyer M., Schuerholz T., Vangerow B., Gratz K.F., Hecker H., et al. Hydroxyethyl starch and modified fluid gelatin maintain plasma volume in a porcine model of septic shock with capillary leakage. Intensive Care Med. 28(5):2002;629-635
46. Marcus B.C., Wyble C.W., Hynes K.L., Gewertz B.L. Cytokine-induced increases in endothelial permeability occur after adhesion molecule expression. Surgery. 120(2):1996;411-416
47. Ballmer-Weber B.K., Dummer R., Kung E., Burg G., Ballmer P.E. Interleukin 2-induced increase of vascular permeability without decrease of the intravascular albumin pool. Br J Cancer. 71(1):1995;78-82
48. Nedrebo T., Reed R.K. Different serotypes of endotoxin (lipopolysaccharide) cause different increases in albumin extravasation in rats. Shock. 18(2):2002;138-141
49. Ruot B., Breuille D., Rambourdin F., Bayle G., Capitan P., Obled C. Synthesis rate of plasma albumin is a good indicator of liver albumin synthesis in sepsis. Am J Physiol Endocrinol Metab. 279(2):2000;E244-E251
50. Barle H., Januszkiewicz A., Hallstrom L., Essen P., McNurlan M.A., Garlick P.J., et al. Albumin synthesis in humans increases immediately following the administration of endotoxin. Clin Sci (Lond). 103(5):2002;525-531
51. Ballmer P.E., McNurlan M.A., Hulter H.N., Anderson S.E., Garlick P.J., Krapf R. Chronic metabolic acidosis decreases albumin synthesis and induces negative nitrogen balance in humans. J Clin Invest. 95(1):1995;39-45
52. Kleger G.R., Turgay M., Imoberdorf R., McNurlan M.A., Garlick P.J., Ballmer P.E. Acute metabolic acidosis decreases muscle protein synthesis but not albumin synthesis in humans. Am J Kidney Dis. 38(6):2001;1199-1207
53. Ernest D., Belzberg A.S., Dodek P.M. Distribution of normal saline and 5% albumin infusions in septic patients. Crit Care Med. 27(1):1999;46-50
54. Rackow E.C., Falk J.L., Fein I.A., Siegel J.S., Packman M.I., Haupt M.T., et al. Fluid resuscitation in circulatory shock: a comparison of the cardiorespiratory effects of albumin, hetastarch, and saline solutions in patients with hypovolemic and septic shock. Crit Care Med. 11(11):1983;839-850
55. Camacho M.T., Totapally B.R., Torbati D., Wolfsdorf J. Pulmonary and extrapulmonary effects of increased colloid osmotic pressure during endotoxemia in rats. Chest. 120(5):2001;1655-1662
56. Kohler J.P., Rice C.L., Zarins C.K., Cammack B.F. III, Moss G.S. Does reduced colloid oncotic pressure increase pulmonary dysfunction in sepsis? Crit Care Med. 9(2):1981;90-93
57. Quinlan G.J., Margarson M.P., Mumby S., Evans T.W., Gutteridge J.M. Administration of albumin to patients with sepsis syndrome: a possible beneficial role in plasma thiol repletion. Clin Sci (Lond). 95(4):1998;459-465
58. Powers K.A., Kapus A., Khadaroo R.G., He R., Marshall J.C., Lindsay T.F., et al. Twenty-five percent albumin prevents lung injury following shock/resuscitation. Crit Care Med. 31(9):2003;2355-2363
59. Smeets H.J., Kievit J., Dulfer F.T., Hermans J., Moolenaar A.J. Analysis of post-operative hypalbuminaemia: a clinical study. Int Surg. 79(2):1994;152-157
60. Hoye R.C., Bennett S.H., Geelhoed G.W., Gorschboth C. Fluid volume and albumin kinetics occurring with major surgery. JAMA. 222(10):1972;1255-1261
61. Woods M.S., Kelley H. Oncotic pressure, albumin and ileus: the effect of albumin replacement on postoperative ileus. Am Surg. 59(11):1993;758-763
62. Zetterstrom H., Hedstrand U. Albumin treatment following major surgery. I. Effects on plasma oncotic pressure, renal function and peripheral oedema. Acta Anaesthesiol Scand. 25(2):1981;125-132
63. Nielsen O.M., Thunedborg P., Jorgensen K. Albumin administration and acute phase proteins in abdominal vascular surgery. A randomised study. Dan Med Bull. 36(5):1989;496-499
64. Nielsen O.M., Engell H.C. Effects of maintaining normal plasma colloid osmotic pressure on renal function and excretion of sodium and water after major surgery. A randomized study. Dan Med Bull. 32(3):1985;182-185
65. Horstick G., Lauterbach M., Kempf T., Ossendorf M., Kopacz L., Heimann A., et al. Plasma protein loss during surgery: beneficial effects of albumin substitution. Shock. 16(1):2001;9-14
66. Atkinson S.D., Tuggle D.W., Tunell W.P. Hypoalbuminemia may predispose infants to necrotizing enterocolitis. J Pediatr Surg. 24(7):1989;674-676
67. Weber T.R., Tracy T.F. Jr., Silen M.L., Powell M.A. Enterostomy and its closure in newborns. Arch Surg. 130(5):1995;534-537
68. Kenny S.E., Pierro A., Isherwood D., Donnell S.C., Van Saene H.K., Lloyd D.A. Hypoalbuminaemia in surgical neonates receiving parenteral nutrition. J Pediatr Surg. 30(3):1995;454-457
69. Ford E.G., Jennings L.M., Andrassy R.J. Serum albumin (oncotic pressure) correlates with enteral feeding tolerance in the pediatric surgical patient. J Pediatr Surg. 22(7):1987;597-599
70. Forse R.A., Shizgal H.M. Serum albumin and nutritional status. JPEN J Parenter Enteral Nutr. 4(5):1980;450-454
71. Fuhrman M.P. The albumin-nutrition connection: separating myth from fact. Nutrition. 18(2):2002;199-200
72. Mora R.J. Malnutrition: organic and functional consequences. World J Surg. 23(6):1999;530-535
73. Starker P.M., LaSala P.A., Forse R.A., Askanazi J., Elwyn D.H., Kinney J.M. Response to total parenteral nutrition in the extremely malnourished patient. JPEN J Parenter Enteral Nutr. 9(3):1985;300-302
74. Erstad B.L., Campbell D.J., Rollins C.J., Rappaport W.D. Albumin and prealbumin concentrations in patients receiving postoperative parenteral nutrition. Pharmacotherapy. 14(4):1994;458-462
75. Brown R.O., Bradley J.E., Bekemeyer W.B., Luther R.W. Effect of albumin supplementation during parenteral nutrition on hospital morbidity. Crit Care Med. 16(12):1988;1177-1182
76. D'Angio R.G. Is there a role for albumin administration in nutrition support? Ann Pharmacother. 28(4):1994;478-482
77. Wojtysiak S.L., Brown R.O., Roberson D., Powers D.A., Kudsk K.A. Effect of hypoalbuminemia and parenteral nutrition on free water excretion and electrolyte-free water resorption. Crit Care Med. 20(2):1992;164-169
78. Koretz R.L. Intravenous albumin and nutrition support: going for the quick fix. JPEN J Parenter Enteral Nutr. 19(2):1995;166-171
79. Kanarek K.S., Williams P.R., Blair C. Concurrent administration of albumin with total parenteral nutrition in sick newborn infants. JPEN J Parenter Enteral Nutr. 16(1):1992;49-53
80. So K.W., Fok T.F., Ng P.C., Wong W.W., Cheung K.L. Randomised controlled trial of colloid or crystalloid in hypotensive preterm infants. Arch Dis Child Fetal Neonatal Ed. 76(1):1997;F43-F46
81. Oca M.J., Nelson M., Donn S.M. Randomized trial of normal saline versus 5% albumin for the treatment of neonatal hypotension. J Perinatol. 23(6):2003;473-476
82. Osborn D.A., Evans N. Early volume expansion for prevention of morbidity and mortality in very preterm infants. Cochrane Database Syst Rev. (4):2001;CD002055
83. Alderson P., Bunn F., Lefebvre C., Li W.P., Li L., Roberts I., et al. Human albumin solution for resuscitation and volume expansion in critically ill patients. Cochrane Database Syst Rev. (1):2002;CD001208
84. Choi P.T., Yip G., Quinonez L.G., Cook D.J. Crystalloids vs. colloids in fluid resuscitation: a systematic review. Crit Care Med. 27(1):1999;200-210
85. Schierhout G., Roberts I. Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: a systematic review of randomised trials. BMJ. 316(7136):1998;961-964
86. Weaver D.W., Ledgerwood A.M., Lucas C.E., Higgins R., Bouwman D.L., Johnson S.D. Pulmonary effects of albumin resuscitation for severe hypovolemic shock. Arch Surg. 113(4):1978;387-392
87. Greenough A., Emery E., Hird M.F., Gamsu H.R. Randomised controlled trial of albumin infusion in ill preterm infants. Eur J Pediatr. 152(2):1993;157-159
88. Kavvadia V., Greenough A., Dimitriou G., Hooper R. Randomised trial of fluid restriction in ventilated very low birthweight infants. Arch Dis Child Fetal Neonatal Ed. 83(2):2000;F91-F96
89. Greenough A., Cheeseman P., Kavvadia V., Dimitriou G., Morton M. Colloid infusion in the perinatal period and abnormal neurodevelopmental outcome in very low birth weight infants. Eur J Pediatr. 161(6):2002;319-323
90. Martin G.S., Mangialardi R.J., Wheeler A.P., Dupont W.D., Morris J.A., Bernard G.R. Albumin and furosemide therapy in hypoproteinemic patients with acute lung injury. Crit Care Med. 30(10):2002;2175-2182
91. Wong W., Fok T.F., Lee C.H., Ng P.C., So K.W., Ou Y., et al. Randomised controlled trial: comparison of colloid or crystalloid for partial exchange transfusion for treatment of neonatal polycythaemia. Arch Dis Child Fetal Neonatal Ed. 77(2):1997;F115-F118
92. Vermeulen L.C. Jr., Ratko T.A., Erstad B.L., Brecher M.E., Matuszewski K.A. A paradigm for consensus. The University Hospital Consortium guidelines for the use of albumin, nonprotein colloid, and crystalloid solutions. Arch Intern Med. 155(4):1995;373-379