Two cases involving clomipramine intoxication

Journal of Analytical Toxicology

Volumn 28, Issue 6, 2004, Pages 504-508

  Avella, Joseph ^a,b   Lehrer, Michael ^a   Katz, Michael ^a   Minden, Edward ^a  

^a U S DEPARTMENT OF HEALTH AND HUMAN SERVICES   (United States)

^b Suffolk County Medical Examiner's Office   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIDEPRESSANT AGENT; BENZATROPINE; CLOMIPRAMINE; CODEINE; DEXTROPROPOXYPHENE; DILTIAZEM; DIPHENHYDRAMINE; DRUG METABOLITE; HYDROCODONE; HYDROMORPHONE; MORPHINE; NORCLOMIPRAMINE; NORPROPOXYPHENE; OPIATE; OXYMORPHONE; PARACETAMOL; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; CASE REPORT; CONFERENCE PAPER; DRUG BLOOD LEVEL; DRUG INTOXICATION; DRUG OVERDOSE; DRUG URINE LEVEL; FEMALE; HUMAN; LABORATORY TEST; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PNEUMONIA;

EID: 4344655924     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/28.6.504     Document Type: Conference Paper

References (14)

1. R.C. Baselt. Disposition of Toxic Drugs and Chemicals in Man, 6th ed. Biomedical Publications, Foster City, CA, 2002, pp 233-234, 53-57.
2. American Hospital Formulary Service Drug Information, G.K. McEvoy, Ed. American Society of Health-System Pharmacists, Bethesda, MD, 2002, pp 2195-2206.
3. S.J. Dencker and A. Nagy. Single versus divided daily dosages of clomipramine. Acta Psych. Scand. 59: 326-334 (1979).
4. A.D. Broadhurst, H.D. James, L. Della Corte, and A.F. Heeley. Clomipramine plasma level and clinical response. Postgrad. Med. J. 53: 139-145 (1977).
5. R.C. Meatherall, D.R.P. Gray, J.L. Chalmers, and J.R. Keenan. A fatal overdose with clomipramine. J. Anal. Toxicol. 7: 168-171 (1983).
6. A.D. Fraser, A.F. Isner, and M.A. Moss. A fatality involving clomipramine. J. Forensic Sci. 31: 762-767 (1986).
7. M. Dalpe-Scott, M. Degouffe, D. Garbutt, and M. Drost. A comparison of drug concentrations in postmortem cardiac and peripheral blood in 320 cases. Can. Soc. Forensic Sci. J. 28: 113-121 (1995).
8. I.M. McIntyre, C.V. King, S.M. Cordner, and O.H. Drummer. Postmortem clomipramine: therapeutic or toxic concentrations. J. Forensic Sci. 39: 486-493 (1994).
9. C.D. Klaassen, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th ed. McGraw-Hill, New York, NY, 2001, pp 1098, 1120.
10. B. Levine, Ed. Principles of Forensic Toxicology. American Association for Clinical Chemistry, Washington, D.C., 1999, p 12.
11. M.J. Ellenhorn, Ed. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning, 2nd ed. Williams & Wilkins, Baltimore, MD, 1997, pp 625-628, 405.
12. Opiates or opioids. Lancet 1: 687 (1983).
13. D.N. Bailey and R.F. Shaw. Interpretation of blood and tissue concentrations in fatal self-ingested overdose involving amitriptyline: an update. J. Anal. Toxicol. 4: 232-236 (1980).
14. D.A. Frommer, K.W. Kulig, J.A. Marx, and B. Rumack. Tricyclic antidepressant overdose: a review. J. Am. Med. Assoc. 257: 219-227 (1987).