Developmental changes in inhibin-α gene expression in the mouse testis

Molecules and Cells

Volumn 17, Issue 1, 2004, Pages 67-72

  Seok, Oye Sun ^b   Ahn, Jung Mi ^b   Mayo, Kelly E ^a   Cho, Byung Nam ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b The Catholic University of Korea   (South Korea)

Author keywords

Fertility; Histology; Inhibin ; Methylation; mRNA

Indexed keywords

INHIBIN; MESSENGER RNA; SEX HORMONE;

ALPHA CHAIN; ANIMAL TISSUE; ARTICLE; BETA CHAIN; CELL POPULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE ACTIVATION; GENE EXPRESSION; HISTOLOGY; HORMONE ACTION; LEYDIG CELL; MALE; MALE FERTILITY; MOUSE; NONHUMAN; NORTHERN BLOTTING; PROTEIN BLOTTING; PROTEIN METHYLATION; PROTEIN SYNTHESIS; SEMINIFEROUS TUBULE; SEXUAL MATURATION; SOUTHERN BLOTTING; SPERMATOZOON MATURATION; TESTIS DEVELOPMENT; TESTIS FUNCTION; TIME;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; BLOTTING, WESTERN; DNA; FERTILITY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INHIBINS; MALE; METHYLATION; MICE; MICE, INBRED ICR; RNA, MESSENGER; TESTIS;

EID: 4344638977     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Boniet, G. and Trasler, J. A. (1994) Developmental expression of DNA methyltransferase messenger ribonucleic acid, protein, and enzyme activity in the mouse testis. Biol. Reprod. 50, 1312-1319.
2. Cho, B.-N., Suh, Y. H., Yoon, Y. D., Lee, C. C., and Kim, K. J. (1993) Progesterone inhibits the estrogen-induced prolactin gene expression in the rat pituitary. Mol. Cell. Endocrinol. 93, 47-52.
3. Cho, B.-N., McMullen, M. L., Pei, L., Yates, J., and Mayo, K. E. (2001) Reproductive deficiencies in transgenic mice expressing the rat inhibin α-subunit gene. Endocrinology 142, 4994-5004.
4. Crawford, R. J., Hammond, V. E., Evans, B. A., Coghan, J. P., Haralambidis, J., Hudson B., Penschow, J., Richards, R., and Treagear, G. (1987) α-inhibin gene expression occurs in the ovine adrenal cortex, and is regulated by adrenocorticotropin. Mol. Endocrinol. 1, 699-706.
5. Feng, Z.-M., Wu, A. Z., and Chen, C.-L. (1998) Testicular GATA-1 factor up-regulates the promoter activity of rat inhibin α-subunit gene in MA-10 Leydig tumor cells. Mol. Endocrinol. 12, 378-390
6. Ito, E., Toki, T., Ishihara, H., Ohtani, H., Gu, L., Yokoyama, M., Engel, J. D., and Yamamoto, M. (1993) Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. Nature 362, 466-468.
7. Ko, J.-Y., Ahn, Y.-L., and Cho, B.-N. (2003) Angiogenesis and white blood cell proliferation induced in mice by injection of a prolactin-expressing plasmid into muscle. Mol. Cells 15, 262-270.
8. Keinan, D., Madigan, M. B., Bardin, W., and Chen, C.-L. (1989) Expression and regulation of testicular inhibin α-subunit gene in vivo and in vitro. Mol. Endocrinol. 3, 29-35.
9. Ling, N., Ying, S. Y., Ueno, N., Esch, F., Denoroy, L., and Guillemin, R. (1985) Isolation and partial characterization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid. Proc. Natl. Acad. Sci. USA 82, 7217-7221.
10. Ling, N., Ying, S. Y., Ueno, N., Shimasaki, S., Esch, F., Hotta, M., and Guillemin, R. (1986a) Pituitary FSH is released by a heterodimer of the β subunits from the two forms of inhibin. Nature 321, 779-782.
11. Ling, N., Ying, S. Y., Ueno, N., Shimasaki, S., Esch, F., Hotta, M., and Guillemin, R. (1986b) A homodimer of the β-subunits of inhibin A stimulates the secretion of pituitary follicle stimulating hormone. Biochem. Biophys. Res. Commun. 138, 1129-1137.
12. Matzuk, M. M., Finegold, M. J., Su, J. G., Hsueh, A. J., and Bradley, A. (1992) α-inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature 360, 313-319.
13. McMullen, M. L., Cho, B.-N., Yates, C. J., and Mayo, K. E. (2001) Gonadal pathologies in transgenic mice expressing the rat inhibin-α subunit. Endocrinology 142, 5005-5014.
14. Mellor, S. L., Richards, M. G., Pedersen, J. S., Robertson, D. M., and Risbridger, G. P. (1998) Loss of the expression and localization of inhibin α-subunit in high grade prostate cancer. J. Clin. Endocrinol. Metab. 83, 969-975.
15. B subunits in ovarian cell types during the rat estrous cycle. Mol. Endocrinol. 2, 1352-1363.
16. B subunits in various tissues predicts diverse functions. Proc. Natl. Acad. Sci. USA 85, 247-251.
17. Miyamoto, K., Hasegawa, Y., Fukuda, M., Nomura, M., Igarashi, M., Kangawa, K., and Matsuo, H. (1985) Isolation of porcine follicular fluid inhibin of 32K daltons. Biochem. Biophys. Res. Commun. 129, 396-403.
18. Ojeda, S. R. and Urbanski, H. F. (1988) in The Physiology of Reproduction, Knobil, E. and Neill, J. (eds.), pp. 1699-1738, Raven Press, New York.
19. Pierson, T. M., Wang, Y., DeMayo, F. J., Matzuk, M. M., Tsai, S. Y., and O'Malley, B. W. (2000) Regulable expression of inhibin A in wild-type and inhibin a null mice. Mol. Endocrinol. 14, 1075-1085.
20. Rivier, J., Spiess, J., McClintock, R., Vaughan, J., and Vale, W. (1985) Purification and partial characterization of inhibin from porcine follicular fluid. Biochem. Biophys. Res. Commun. 133, 120-127.
21. Roberts, V., Meunier, H., Sawchenko, P. E., and Vale, W. (1989) Differential production and regulation of inhibin subunits in rat testicular cell types. Endocrinology 125, 3122-3129.
22. Robertson, D. M., Foulds, L. M., Leversha, L., Morgan, F. J., Hearn, M. T., Burger, H. G., Wettenhall, R. E., and de Krester, D. M. (1985) Isolation of inhibin from bovine follicular fluid. Biochem. Biophys. Res. Commun. 126, 220-226.
23. Schmitt, J. F., Millar, D. S., Pedersen, J. S., Clark, S. L., Venter, D. J., Frydenberg, M., Molloy, P. L., and Risbridger, G. P. (2002) Hypermethylation of the inhibin α-subunit gene in prostate carcinoma. Mol. Endocrinol. 16, 213-220.
24. Sharpe, R. M., Turner, K. J., McKinnell, C., Groome, N. P., Atanassova, N., Millar, M. R., Buchanan, D. L., and Cooke, P. S. (1999) Inhibin B levels in plasma of the male rat from birth to adulthood: effect of experimental manipulation of Sertoli cell number. J. Androl. 20, 94-101.
25. Su, J.-G. and Hsueh, A. J. W. (1992) Characterization of mouse inhibin α gene and its promoter. Biochem. Biophys. Res. Commun. 186, 293-300.
26. Tone, S., Katoh, Y., Fujimoto, H., Togashi, S., Yanazawa, M., Kato, Y., and Higashinakagawa, T. (1990) Expression if inhibin α -subunit gene during mouse gametogenesis. Differentiation 44, 62-68.
27. Vale, W., Rivier, J., Vaughan, J., McClintock, R., Corrigan, A., Woo, W., Karr, D., and Spiess, J. (1986) Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid. Nature 321, 776-779.
28. Woodruff, T. K., D'Agostino, J., Schwartz, N. B., and Mayo, K. E. (1989) Decreased inhibin gene expression in preovulatory follicles requires primary gonadotropin surges. Endocrinology 124, 2193-2199.
29. Woodruff, T. K., Besecke, L. M., Groome, N., Draper, L. B., Schwartz, N. B., and Weiss J. (1996) Inhibin A and inhibin B are inversely correlated to follicle-stimulating hormone, yet are discordant during the follicular phage of the rat estrous cycle, and inhibin A is expressed in a sexually dimorphic manner. Endocrinology 137, 5463-5467.
30. Zhang, Z., Wu, A. Z., Feng, Z.-M., Mruk, D., Cheng, Y., and Chen, C.-L. (2002) Gonadotropins, via cAMP, negatively regulate GATA-1 gene expression in testicular cells. Endocrinology 143, 829-836.