Development of granulomatous common variable immunodeficiency subsequent to infection with Toxoplasma gondii

Clinical and Experimental Immunology

Volumn 137, Issue 3, 2004, Pages 578-583

  Mrusek, S ^a   Marx, A ^b   Kummerle Deschner J ^c   Tzaribachev, N ^c   Enders, A ^a   Riede, U N ^a   Warnatz, K ^d   Dannecker, G E ^e   Ehl, Stephan ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

^e OLGAHOSPITAL   (Germany)

Author keywords

Common variable immunodeficiency; Granuloma; Hypogammaglobulinaemia sarcoidosis; Toxoplasma gondii

Indexed keywords

CD4 ANTIGEN; DIPEPTIDYL CARBOXYPEPTIDASE; INTERLEUKIN 2 RECEPTOR; TUMOR NECROSIS FACTOR;

ARTICLE; B LYMPHOCYTE; BIOPSY; CASE REPORT; CLINICAL FEATURE; COMMON VARIABLE IMMUNODEFICIENCY; DISEASE ASSOCIATION; DISEASE COURSE; ENZYME BLOOD LEVEL; FEMALE; GRANULOMATOUS COMMON VARIABLE IMMUNODEFICIENCY; GRANULOMATOUS INFLAMMATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOGAMMAGLOBULINEMIA; LIVER; LUNG; LYMPH NODE; MEMORY CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCHOOL CHILD; T LYMPHOCYTE ACTIVATION; TOXOPLASMA GONDII; TOXOPLASMOSIS;

EID: 4344637634     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02558.x     Document Type: Article

References (21)

1. Durandy A, Honjo T. Human genetic defects in class-switch recombination (hyper-IgM syndromes). Curr Opin Immunol 2001; 13:543-8.
2. Morra M, Silander O, Calpe S et al. Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome. Blood 2001; 98:1321-5.
3. Grimbacher B, Hutloff A, Schlesier M et al. Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency. Nat Immunol 2003; 4:261-8.
4. Vorechovsky I, Cullen M, Carrington M, Hammarstrom L, Webster AD. Fine mapping of IGAD1 in IgA deficiency and common variable immunodeficiency: identification and characterization of haplotypes shared by affected members of 101 multiple-case families. J Immunol 2000; 164:4408-16.
5. Spickett GP, Farrant J, North ME, Zhang JG, Morgan L, Webster AD. Common variable immunodeficiency: how many diseases? Immunol Today 1997; 18:325-8.
6. Soresina A, Lougaris V, Giliani S et al. Mutations of the X-linked lymphoproliferative disease gene SH2D1A mimicking common variable immunodeficiency. Eur J Pediatr 2002; 161:656-9.
7. Fasano MB, Sullivan KE, Sarpong SB et al. Sarcoidosis and common variable immunodeficiency. Report of 8 cases and review of the literature. Medicine (Baltimore) 1996; 75:251-61.
8. Mechanic LJ, Dikman S, Cunningham-Rundles C. Granulomatous disease in common variable immunodeficiency. Ann Intern Med 1997; 127:613-7.
9. Ströbel P, Nanan R, Gattenlöhner S et al. Reversible monoclonal lymphadenopathy in autoimmune lymphoproliferative syndrome with functional Fas (CD95/APo-1) defiency. Am J Surg Pathol 1999; 23:829-37.
10. Warnatz K, Denz A, Drager R et al. Severe deficiency of switched memory B cells (CD27(+) IgM(-) IgD(-) in subgroups of patients with common variable immunodeficiency: a new approach to classify a heterogeneous disease. Blood 2002; 99:1544-51.
11. Shachor J, Shneyour A, Radnay J, Steiner ZP, Bruderman I. Toxoplasmosis in a patient with common variable immunodeficiency. Am J Medical Sci 1984; 287:36-8.
12. Ameratunga R, Becroft DM, Hunter W. The simultaneous presentation of sarcoidosis and common variable immune deficiency. Pathology 2000; 32:280-2.
13. Kanathur N, Byrd RP Jr, Fields CL, Roy TM. Noncaseating granulomatous disease in common variable immunodeficiency. South Med 2000; 93:631-3.
14. Mullighan CG, Fanning GC, Chapel HM, Welsh KI. TNF and lymphotoxin-alpha polymorphisms associated with common variable immunodeficiency: role in the pathogenesis of granulomatous disease. J Immunol 1997; 159:6236-41.
15. Spickett GP, Zhang JG, Green T, Shrimankar J. Granulomatous disease in common variable immunodeficiency, effect on immunoglobulin replacement therapy and response to steroids and splenectomy. J Clin Pathol 1996; 49:431-4.
16. Sutor G, Fabel H. Sarcoidosis and common variable immunodeficiency. A case of a malignant course of sarcoidosis in conjunction with severe impairment of the cellular and humoral immune system. Respiration 2000; 67:204-8.
17. Aukrust P, Lien E, Kristoffersen AK et al. Persistent activation of the tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency - possible immunologic and clinical consequences. Blood 1996; 87:674-81.
18. Wright JJ, Wagner DK, Blaese RM, Hagengruber C, Waldmann TA, Fleisher TA. Characterization of common variable immunodeficiency: identification of a subset of patients with distinctive immunophenotypic and clinical features. Blood 1990; 76:2046-51.
19. Crofts MJ, Joyner MV, Sharp JC, Costello J, Vergani D. Sarcoidosis associated with combined immunodeficiency. Postgrad Med 1980; 56:263-5.
20. Edelstein AD, Miller A, Zimelman AP, Rocklin RE, Neiman RS. Adult severe combined immunodeficiency and sarcoid-like granulomas with hypersplenism. Am J Hematol 1978; 5:55-62.
21. Perks WH, Petheram IS. Familial combined cellular and humoral immune defect with multisystem granulomata. Thorax 1978; 33:101-5.