Endocrine pancreatic dysfunction in HIV-infected children: Association with growth alterations

Journal of Infectious Diseases

Volumn 190, Issue 5, 2004, Pages 908-912

  Rondanelli, Mariangela ^a,c   Caselli, Desiree ^a   Trotti, Rosita ^a   Solerte, Sebastiano Bruno ^a   Maghnie, Mohamed ^a   Maccabruni, Anna ^b   Minoli, Lorenzo ^b   Ferrari, Ettore ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c Istituto Santa Margherita   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; CORTICOTROPIN; GLUCAGON; GLUCOSE; GROWTH HORMONE; HYDROCORTISONE; INSULIN; LIPID; PROTEINASE INHIBITOR; THYROTROPIN;

AGE DISTRIBUTION; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL EXAMINATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FAILURE TO THRIVE; FEMALE; FOLLOW UP; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; GROWTH DISORDER; HOMEOSTASIS; HORMONE BLOOD LEVEL; HORMONE RELEASE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INSULIN BLOOD LEVEL; LABORATORY TEST; MALE; MODEL; PANCREAS FUNCTION DISORDER; PANCREAS ISLET DISEASE; PANCREAS SECRETION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEX;

BLOOD GLUCOSE; C-PEPTIDE; CHILD; FEMALE; GLUCAGON; GROWTH DISORDERS; HIV INFECTIONS; HOMEOSTASIS; HORMONES; HUMANS; INSULIN; LIPIDS; MALE; PANCREAS; PROSPECTIVE STUDIES;

EID: 4344613593     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/422255     Document Type: Article

References (39)

1. Roubenoff R. Inflammatory and hormonal mediators of cachexia. J Nutr 1997; 127(Suppl 5):1014S-6S.
2. Safrin S, Grunfeld C. Fat distribution and metabolic changes in patients with HIV infection. AIDS 1999; 13:2493-505.
3. Grunfeld C, Feingold KR. Metabolic disturbances and wasting in the acquired immunodeficiency syndrome. N Engl J Med 1992; 327:329-37.
4. Behrens G, Dejam A, Schmidt H, et al. Impaired glucose tolerance, beta cell function and lipid metabolism in HIV patients under treatment with protease inhibitors. AIDS 1999; 13:F63-70.
5. Tovo PA, de Martino M, Gabiano C, et al. Prognostic factors and survival in children with perinatal HIV-1 infection. The Italian Register for HIV Infections in Children. Lancet 1992; 339:1249-523.
6. Brettler DB, Forsberg A, Bolivar E, Brewster F, Sullivan J. Growth failure as a prognostic indicator for progression to acquired immunodeficiency syndrome in children with hemophilia. J Pediatr 1990; 117:584-8.
7. Scott GB, Buck BE, Leterman JG, Bloom FL, Parks WP. Acquired immunodeficiency syndrome in infants. N Engl J Med 1984; 310:76-81.
8. Gertner JM, Kaufman FR, Donfield SM, et al. Delayed somatic growth and pubertal development in human immunodeficiency virus-infected hemophiliac boys: Hemophilia Growth and Development Study. J Pediatr 1994; 124:896-902.
9. Centers for Disease Control and Prevention. 1994 Revised classification system for human immunodeficiency virus infection in children less than 13 years of age. MMWR Recomm Rep 1994; 12:1-10.
10. Greulich WW, Pyle SI. Radiographic atlas of skeletal development of the hand and wrist. 2nd ed. Stanford, CA: Stanford University Press, 1959.
11. Tanner JM, Whitehouse RH. Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Arch Dis Child 1976; 51:170-9.
12. Hughes IA. Handbook of endocrine tests in children. Bristol, England: John Wright & Sons, 1990.
13. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in men. Diabetologia 1985; 28:412-9.
14. Heijligenberg R, Sauerwein HP, Brabant G, Endert E, Hommes MJ, Romijn JA. Circadian growth hormone secretion in asymptomatic human immune deficiency virus infection and acquired immunodeficiency syndrome. J Clin Endocrinol Metab 1996; 81:4028-32.
15. Verges B, Chavanet P, Desgres J, et al. Adrenal function in HIV infected patients. Acta Endocrinol (Copenh) 1989; 121:633-7.
16. Dluhy RG. The growing spectrum of HIV-related endocrine abnormalities. J Clin Endocrinol Metab 1990; 70:563-5.
17. Mulder JW, Frissen PH, Krijnen P, et al. Dehydroepiandrosterone as predictor for progression to AIDS in asymptomatic human immunodeficiency virus-infected men. J Infect Dis 1992; 165:413-8.
18. Azar ST, Melby JC. Hypothalamic-pituitary-adrenal function in non-AIDS patients with advanced HIV infection. Am J Med Sci 1993; 305:321-5.
19. Findling JW, Buggy BP, Gilson IH, Brummitt CF, Bernstein BM, Raff H. Longitudinal evaluation of adrenocortical function in patients infected with the human immunodeficiency virus. J Clin Endocrinol Metab 1994; 79:1091-6.
20. Membreno L, Irony I, Dere W, Klein R, Biglieri EG, Cobb E. Adrenocortical function in acquired immunodeficiency syndrome. J Clin Endocrinol Metab 1987; 65:482-7.
21. Bateman A, Singh A, Kral T, Solomon S. The immune-hypothalamic-pituitary- adrenal axis. Endocr Rev 1989; 10:92-112.
22. Norbiato G, Bevilacqua M, Vago T, Clerici M. Glucocorticoids and interferon-alpha in the acquired immunodeficiency syndrome. J Clin Endocrinol Metab 1996; 81:2601-6.
23. Solerte SB, Rondanelli M, Fioravanti M, et al. Impaired regulation of GH-IGF-I-IGFBP3 axis and ACTH-adrenal function in AIDS patients (CDC IVC) with wasting syndrome: a possible defensive mechanism. J Endocrinol Invest 1995; 18:43.
24. Rondanelli M, Scevola D, Solerte SB, Locatelli M, Minoli L, Ferrari E. Circadian secretory pattern of growth factor, insulin-like growth factor type I, cortisol, adrenocorticotropic hormone, thyroid-stimulating hormone, and prolactin during HIV infection. AIDS Res Hum Retroviruses 1997; 13:1243-9.
25. Bhasin S, Singh AB, Javanbakht M. Neuroendocrine abnormalities associated with HIV infection. Endocrinol Metab Clin North Am 2001; 30:749-64.
26. Schwartz LJ, St Louis Y, Wu R, Wiznia A, Rubinstein A, Saenger P. Endocrine function in children with human immunodeficiency virus infection. Am J Dis Child 1991; 145:330-3.
27. Lepage P, Van de Perre P, Van Vliet G, et al. Clinical and endocrinologic manifestations in perinatally acquired human immunodeficiency virus type 1-infected children aged 5 years or older. Am J Dis Child 1991; 145:1248-51.
28. Matarazzo P, Palomba E, Lala R, et al. Growth impairment, IGF I hyposecretion and thyroid dysfunction in children with perinatal HIV-1 infection. Acta Paediatr 1994; 83:1029-34.
29. Hirschfeld S, Laue L, Cutler GB Jr, Pizzo PA. Thyroid abnormalities in children infected with human immunodeficiency virus. J Pediatr 1996; 128:70-4.
30. Blethen SL, Nachman S, Chasalow FI. Thyroid function in children with perinatally acquired antibodies to human immunodeficiency virus. J Pediatr Endocrinol 1994; 7:201-4.
31. Geffner M, Yeh DY, Landaw EM, et al. In vitro insulin-like growth factor-I, growth hormone, and insulin resistance occurs in symptomatic human immunodeficiency virus-1-infected children. Pediatr Res 1993; 34:66-72.
32. Lala R, Palomba E, Matarazzo MD, Altare F, Tovo PA. ACTH and cortisol secretions in children with perinatal HIV-1 infection. Pediatr AIDS HIV Infect 1996; 7:243-5.
33. Rondanelli M, Caselli D, Aricò M, et al. Insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 response to growth hormone is impaired in HIV-infected children. AIDS Res Hum Retroviruses 2002; 18:331-9.
34. Oberfield SE, Kairam R, Bakshi S, et al. Steroid response to adrenocorticotropin stimulation in children with human immunodeficiency virus infection. J Clin Endocrinol Metab 1990; 70:578-81.
35. Azzari C, Rossi ME, Resti M, et al. Changed levels of substance P and somatostatin in HIV-positive children. Pediatr Med Chir 1992; 14:577-81.
36. Kino T, Chrousos GP. AIDS-related insulin resistance and lipodystrophy syndrome. Curr Drug Targets Immune Endocr Metabol Disord 2003; 3:111-7.
37. Kino T, Mirani M, Alesci S, et al. AIDS-related lipodystrophy/insulin resistance syndrome. Horm Metab Res 2003; 35:129-36.
38. Benjamin DK Jr, Miller W, Benjamin DK, et al. A comparison of height and weight velocity as a part of the composite endpoint in pediatric HIV. AIDS 2003; 17:2331-36.
39. Tsigos C, Papanicolau DA, Kyrou I, Defensor R, Mitsiadis CS, Chrousos GP. Dose-dependent effects of recombinant human interleukin-6 on glucose regulation. J Clin Endocrinol Metab 1997; 82:4167-70.