Effects of Helicobacter pylori on endothelial cell proliferation and chemotaxis

Digestion

Volumn 69, Issue 4, 2004, Pages 201-210

  Pearce, Hannah Rose ^a   Kalia, Neena ^a   Bardhan, Karna Dev ^a   Atherton, John Christopher ^a   Brown, Nicola Jane ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Angiogenesis; Endothelial cell cycle; Endothelial cells, proliferation chemotaxis; Helicobacter pylori

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; CAMPYLOBACTER JEJUNI; CELL CYCLE S PHASE; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ESCHERICHIA COLI; FLOW CYTOMETRY; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MEDICAL ASSESSMENT; NEUTROPHIL CHEMOTAXIS; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PEPTIC ULCER; PRIORITY JOURNAL;

CAMPYLOBACTER JEJUNI; CELL CULTURE TECHNIQUES; CELL DIVISION; CELL MOVEMENT; CHEMOTAXIS; ENDOTHELIAL CELLS; ESCHERICHIA COLI; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; NEOVASCULARIZATION, PATHOLOGIC; PEPTIC ULCER; UMBILICAL VEINS;

EID: 4344607480     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000079149     Document Type: Article

References (56)

1. Kelly DJ: The physiology and metabolism of the human gastric pathogen Helicobacter pylori. Adv Microb Physiol 1998;40:137-189.
2. Calam J: Clinical science of Helicobacter pylori infection: Ulcers and NSAIDs. Br Med Bull 1998;54:55-62.
3. Blaser M: Science, medicine, and the future: Helicobacter pylori and gastric diseases. BMJ 1998;316:1507-1510.
4. Censini S, Lange C, Xiang Z, Crabtree JE, Ghiara P, Borodovsky M, Rappuoli R, Covacci A: cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci U S A 1996;93:14648-14653.
5. Atherton JC: H. pylori virulence factors. Br Med Bull 1998;54:105-120.
6. Atherton JC, Cao P, Peek RM Jr, Tummuru MK, Blaser MJ, Cover TL: Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori: Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem 1995;270:17771-17777.
7. van Doorn LJ, Figueiredo C, Sanna R, Blaser MJ, Quint WG: Distinct variants of Helicobacter pylori cagA are associated with vacA subtypes. J Clin Microbiol 1999;37:2306-2311.
8. Atherton JC, Peek RM Jr, Tham KT, Cover TL, Blaser MJ: Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori. Gastroenterology 1997;112:92-99.
9. Segal ED, Cha J, Lo J, Falkow S, Tompkins LS: Altered states: Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc Natl Acad Sci USA 1999;96:14559-14564.
10. Brzozowski T, Konturek PC, Konturek SJ, Karczewska E, Pajdo R, Stachura J, Ghiara P, Hahn EGl: Gastric secretion and ulcer healing in mouse stomach infected with cytotoxin expressing strain of Helicobacter pylori. J Physiol Pharmacol 1998;49:387-403.
11. Brzozowski T, Konturek PC, Konturek JW, et al: Water extracts of Helicobacter pylori delay healing of chronic gastric ulcers in rats: Role of cytokines and gastrin-somatostatin link. Digestion 1998;60:22-33.
12. Ross JS, Bui HX, del Rosario A, Sonbati H, George M, Lee CY: Helicobacter pylori: Its role in the pathogenesis of peptic ulcer disease in a new animal model. Am J Pathol 1992;141: 721-727.
13. Tarnawski A, Halter F: Cellular mechanisms, interactions, and dynamics of gastric ulcer healing. J Clin Gastroenterol 1995;21(suppl 1): S93-S97.
14. Arnold F, West DC: Angiogenesis in wound healing. Pharmacol Ther 1991;52:407-422.
15. Taha AS, Huxham IM, Motley P, Morton R, Beattie AD: Reduced gastric mucosal vascularity in patients with chronic gastritis. Eur J Gastroenterol Hepatol 1998;10:1001-1005.
16. Szabo S, Folkman J, Vattay P, Morales RE, Pinkus GS, Kato K: Accelerated healing of duodenal ulcers by oral administration of a mutein of basic fibroblast growth factor in rats. Gastroenterology 1994;106:1106-1111.
17. Szabo S, Vincze A, Sandor Z, Jadus M, Gombos Z, Pedram A, Levin E, Hagar J, Iaquinto G: Vascular approach to gastroduodenal ulceration: New studies with endothelins and VEGF. Dig Dis Sci 1998;43(9 suppl):40S-45S.
18. Fajardo LF: The complexity of endothelial cells: A review. Am J Clin Pathol 1989;92:241-250.
19. Folkman J, Shing Y: Angiogenesis. J Biol Chem 1992;267:10931-10934.
20. Pepper MS, Mandriota SJ, Vassalli JD, Orci L, Montesano R: Angiogenesis-regulating cytokines: Activities and interactions. Curr Top Microbiol Immunol 1996;213:31-67.
21. Tarnawski A, Hollander D, Stachura J, Gergely H, Krause WJ, Sarfeh IJ: Role of angiogenesis in healing of experimental gastric ulcer; in Halter F, Garner A, Tytgat GN (eds): Mechanisms of Peptic Ulcer Healing. Dordrecht, Kluwer, 1991, pp 165-171.
22. Kurosawa A, Miwa H, Hirose M, Tsune I, Nagahara A, Sato N: Inhibition of cell proliferation and induction of apoptosis by Helicobacter pylori through increased phosphorylated p53, p21 and Bax expression in endothelial cells. J Med Microbiol 2002;51:385-391.
23. Peek RM Jr, Wirth HP, Moss SF, Yang M, Abdalla AM, Tham KT, Zhang T, Tang LH, Modlin IM, Blaser MJ: Helicobacter pylori alters gastric epithelial cell cycle events and gastrin secretion in Mongolian gerbils. Gastroenterology 2000;118:48-59.
24. Anti M, Armuzzi A, Gasbarrini A, Gasbarrini G: Importance of changes in epithelial cell turnover during Helicobacter pylori infection in gastric carcinogenesis. Gut 1998;43(suppl 1): S27-S32.
25. El-Zimaity HM, Graham DY, Genta RM, Lechago J: Sustained increase in gastric antral epithelial cell proliferation despite cure of Helicobacter pylori infection. Am J Gastroenterol 2000;95:930-935.
26. Moss SF, Calam J, Agarwal B, Wang S, Holt PR: Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut 1996;38:498-501.
27. Kalia N, Bardhan KD: Of blood and guts: Association between Helicobacter pylori and the gastric microcirculation. J Gastroenterol Hepatol 2003;18:1010-1017.
28. Rokkas T, Ladas S, Liatsos C, Petridou E, Papatheodorou G, Theocharis S, Karameris A, Raptis S: Relationship of Helicobacter pylori CagA status to gastric cell proliferation and apoptosis. Dig Dis Sci 1999;44:487-493.
29. Chang K, Fujiwara Y, Wyle F, Tarnawski A: Helicobacter pylori toxin inhibits growth and proliferation of cultured gastric cells-Kato III. J Physiol Pharmacol 1993;44:17-22.
30. Knipp U, Birkholz S, Kaup W, Opferkuch W: Partial characterization of a cell proliferationinhibiting protein produced by Helicobacter pylori. Infect Immun 1996;64:3491-3496.
31. Wagner S, Beil W, Westermann J, Logan RP, Bock CT, Trautwein C, Bleck JS, Manns MP: Regulation of gastric epithelial cell growth by Helicobacter pylori: Offdence for a major role of apoptosis. Gastroenterology 1997;113: 1836-1847.
32. Paziak-Domanska B, Chmiela M, Jarosinska A, Rudnicka W: Potential role of CagA in the inhibition of T cell reactivity in Helicobacter pylori infections. Cell Immunol 2000;202:136-139.
33. Shirin H, Sordillo EM, Oh SH, Yamamoto H, Delohery T, Weinstein IB, Moss SF: Helicobacter pylori inhibits the G1 to S transition in AGS gastric epithelial cells. Cancer Res 1999; 59:2277-2281.
34. Ahmed A, Smoot D, Littleton G, Tackey R, Walters CS, Kashanchi F, Allen CR, Ashktorab H: Helicobacter pylori inhibits gastric cell cycle progression. Microbes Infect 2000;2:1159-1169.
35. Pai R, Cover T, Tarnawski A: Helicobacter pylori vacuolating cytotoxin (VacA) disorganizes the cytoskeletal architecture of gastric epithelial cells. Biochem Biophys Res Commun 1999;262:245-250.
36. Obst B, Wagner S, Sewing KF, Beil W: Helicobacter pylori causes DNA damage in gastric epithelial cells. Carcinogenesis 2000;21:1111-1115.
37. Mannick EE, Bravo LE, Zarama G, Realpe JL, Zhang XJ, Ruiz B, Fontham ET, Mera R, Miller MJ, Correa P: Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. Cancer Res 1996;56:3238-3243.
38. Jones NL, Shannon PT, Cutz E, Yeger H, Sherman PM: Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection. Am J Pathol 1997;151:1695-1703.
39. Kalia N, Jones C, Bardhan DK, Reed MW, Atherton JC, Brown NJ: Effects of genotypically different strains of Helicobacter pylori on human microvascular endothelial cells in vitro. Dig Dis Sci 2001;46:54-61.
40. Lang I, Hoffmann C, Olip H, Pabst MA, Hahn T, Dohr G, Desoye G: Differential mitogenic responses of human macrovascular and microvascular endothelial cells to cytokines underline their phenotypic heterogeneity. Cell Prolif 2001;34:143-155.
41. Craig LE, Spelman JP, Strandberg JD, Zink MC: Endothelial cells from diverse tissues exhibit differences in growth and morphology. Microvasc Res 1998;55:65-76.
42. Cover TL, Tummuru MK, Cao P, Thompson SA, Blaser MJ: Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains. J Biol Chem 1994; 269:10566-10573.
43. Studzinski GP: Cell Growth and Apoptosis: A Practical Approach. Oxford, Oxford University Press, 1995.
44. Stratford IJ, Stephens MA: The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay. Int J Radiat Oncol Biol Phys 1988;16:973-976.
45. Crissman HA: Cell cycle analysis by flow cytometry; in Studzinski G (ed): Cell Growth and Apoptosis: A Practical Approach. Oxford, IRL Press, 1995, pp 21-42.
46. Lawry J: DNA staining for flow cytometry. Proc Royal Microscopical Society 2001;36:61-65.
47. Brown NJ, Staton CA, Rodgers GR, Corke KP, Underwood JCE, Lewis CE: Fibrinogen E fragment selectively disrupts the vasculature and inhibits the growth of tumours in a syngeneic murine model. Br J Cancer 2002;86:1813-1816.
48. Kim JS, Kim JM, Ko EJ, Kim H, Jung HC, Song IS: Helicobacter pylori down-regulates the receptors of vascular endothelial growth factor and angiopoietin in vascular endothelial cells (abstract). Gastroenterology 2002;122:223.
49. Slomiany BL, Piotrowski J, Slomiany A: Susceptibility of growth factors to degradation by Helicobacter pylori protease: Effect of ebrotidine and sucralfate. Biochem Mol Biol Int 1996;40:209-215.
50. Ascencio F, Hansson HA, Larm O, Wadstrom T: Helicobacter pylori interacts with heparin and heparin-dependent growth factors. FEMS Immunol Med Microbiol 1995;12:265-272.
51. Jenkinson L, Bardhan KD, Atherton JC, Kalia N: Helicobacter pylori prevents proliferative stage of angiogenesis in vitro: Role of cytokines. Dig Dis Sci 2002;47:1857-1862.
52. Ricci V, Ciacci C, Zarrilli R, Sommi P, Tummuru MK, Del Vecchio Blanco C, Bruni CB, Cover TL, Blaser MJ, Romano M: Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: Role of VacA and CagA. Infect Immun 1996;64:2829-2833.
53. Hofman V, Ricci V, Galmiche A, Brest P, Auberger P, Rossi B, Boquet P, Hofman P: Effect of Helicobacter pylori on polymorphonuclear leukocyte migration across polarized T84 epithelial cell monolayers: Role of vacuolating toxin VacA and cag pathogenicity island. Infect Immun 2000;68:5225-5233.
54. Akyon Y, Hascelik G: The effect of Helicobacter pylori on neutrophil chemotaxis is independent of cagA. FEMS Immunol Med Microbiol 1999;24:209-213.
55. Supajatura V, Ushio H, Wada A, Yahiro K, Okumura K, Ogawa H, Hirayama T, Ra C: Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines. J Immunol 2002;168:2603-2607.
56. Gunawan E, Tsuji S, Tsujii M, Kimura A, Sun WH, Sawaoka H, Sasayama Y, Sasaki Y, Kawano S, Hori M: Influences of Helicobacter pylori on gastric angiogenesis and ulcer healing in mice. J Gastroenterol Hepatol 2002;17:960-965.