Immunohistochemical stains fail to increase the detection rate of micrometastatic melanoma in completion regional lymph node dissection specimens

Melanoma Research

Volumn 14, Issue 4, 2004, Pages 263-268

  Scolyer, Richard A ^a   Li, Ling Xi L ^a   McCarthy, Stanley W ^a   Shaw, Helen M ^a,b   Stretch, Jonathan R ^a,b   Sharma, Raghwa ^a,c   Thompson, John F ^a,b  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c WESTMEAD HOSPITAL   (Australia)

Author keywords

HMB45; Immunohistochemistry; Lymph node; Melanoma; Micrometastases; Pathology; Regional node field; S100; Sentinel node

Indexed keywords

ARTICLE; CANCER CELL; CANCER DIAGNOSIS; CLINICAL ARTICLE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE; LYMPH NODE DISSECTION; MELANOMA; PRIORITY JOURNAL;

HUMANS; IMMUNOHISTOCHEMISTRY; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MELANOMA; STAINING AND LABELING;

EID: 4344603959     PISSN: 09608931     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.cmr.0000136708.90534.71     Document Type: Article

References (28)

1. Veronesi V. Prognostic factors in malignant melanoma. In: Veronesi V, Cascinelli N, Santinami M (editors): Cutaneous melanoma: status of knowledge and furture perspective. Orlando, FL: Academic Press; 1987. pp. 99-110.
2. Gershewald JE, Balch CM, Soong S-J, Thompson JF. Prognostic factors and natural history. In: Balch CM, Houghton AN, Sober AJ, Soong S-J (editors): Cutaneous melanoma. St Louis, MO: Quality Medical Publishing Inc; 2003. pp. 25-54.
3. Cascinelli N, Belli F, Santinami M, Fait V, Testori A, Ruka W, et al. Sentinel lymph node biopsy in cutaneous melanoma: the WHO Melanoma Program experience. Ann Surg Oncol 2000; 7:469-474.
4. Morton DL, Wen DR, Wong JH, Economou JS, Cagle LA, Storm FK, et al. Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg 1992; 127:392-399.
5. Thompson JF. Sentinel node biopsy. J Surg Oncol 1997; 66:270-272.
6. Thompson JF, Uren RF. What is a 'sentinel' lymph node? Eur J Surg Oncol 2000; 26:103-104.
7. Balch CM, Soong SJ, Gershenwald JE, Thompson JF, Reintgen DS, Cascinelli N, et al. Prognostic factors analysis of 17 600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol 2001; 13:3622-3634.
8. Morton DL, Thompson JF, Essner R, Elashoff R, Stern SL, Nieweg OE, et al. Validation of the accuracy of intraoperative lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: a multicenter trial. Multicenter Selective Lymphadenectomy Trial Group. Ann Surg 1999; 230:453-463.
9. Gadd MA, Cosimi AB, Yu J, Duncan LM, Yu L, Flotte TJ, et al. Outcome of patients with melanoma and histologically negative sentinel lymph nodes. Arch Surg 1999; 134:381-387.
10. Gibbs JF, Huang PP, Zhang PJ, Kraybill WG, Cheney R. Accuracy of pathologic techniques for the diagnosis of metastatic melanoma in sentinel lymph nodes. Ann Surg Oncol 1999; 6:699-704.
11. Yu LL, Flotte TJ, Tanabe KK, Gadd MA, Cosimi AB, Sober AJ, et al. Detection of microscopic melanoma metastases in sentinel lymph nodes. Cancer 1999; 86:617-627.
12. Gershenwald JE, Colome MI, Lee JE, Mansfield PF, Tseng C, Lee JJ, et al. Patterns of recurrence following a negative sentinel lymph node biopsy in 243 patients with stage I or II melanoma. J Clin Oncol 1998; 16:2253-2260.
13. Cochran AJ. Surgical pathology remains pivotal in the evaluation of 'sentinel' lymph nodes. Am J Surg Pathol 1999; 23:1169-1172.
14. Messina JL, Glass LF, Cruse CW, Berman C, Ku NK, Reintgen DS. Pathologic examination of the sentinel lymph node in malignant melanoma. Am J Surg Pathol 1999; 23:686-690.
15. Baisden BL, Askin FB, Lange JR, Westra WH. HMB-45 immunohistochemical staining of sentinel lymph nodes: a specific method for enhancing detection of micrometastases in patients with melanoma. Am J Surg Pathol 2000; 24:1140-1146.
16. Li L-XL, Scolyer RA, Ka VSK, McKinnon JG, Shaw HM, McCarthy SW, et al. Pathologic review of negative sentinel lymph nodes in melanoma patients with regional recurrence: a clinicopathologic study of 1152 patients undergoing sentinel lymph node biopsy. Am J Surg Pathol 2003; 27: 197-202.
17. Cook MG, Green MA, Anderson B, Eggermont AM, Ruiter DJ, Spatz A, et al. The development of optimal pathological assessment of sentinel lymph nodes for melanoma. J Pathol 2003; 200:314-319.
18. Cochran AJ, Wen DR, Morton DL. Occult tumor cells in the lymph nodes of patients with pathological stage I malignant melanoma. An immunohistological study. Am J Surg Pathol 1988; 12:612-618.
19. Shidham VB, Qi DY, Acker S, Kampalath B, Chang CC, George V, et al. Evaluation of micrometastases in sentinel lymph nodes of cutaneous melanoma: higher diagnostic accuracy with Melan-A and MART-1 compared with S-100 protein and HMB-45. Am J Surg Pathol 2001; 25:1039-1046.
20. Matter M, Willi J-P, Pillevuit O, Guggisberg D, Cerrotini J-P, Gugerli O, et al. Sentinel lymph node dissection (SLND) and elective lymph node dissection (ELND) in melanoma patients. In: Kitajima M, Thompson JF (editors): Proceedings of the Third International Sentinel Node Congress, Yokohama, Japan, 2002, p. 153.
21. Caraco C, Chiofalo MG, Niro J, Ascierto PA, Botti G, Lastoria S, Mozzillo N. Sentinel lymph node biopsy to stage patients with cutaneous melanoma at the National Cancer Institute of Naples. Results from 240 Sentinal node biopsies. Tumori 2002; 88:512-513.
22. Scolyer RA, Li L-XL, McCarthy SW, Thompson JF. Can pathological features of positive sentinel nodes predict further nodal involvement in regional node fields of melanoma patients? In: Kitajima M, Thompson JF (editors): Proceedings of the Third International Sentinel Node Congress, Yokohama, Japan, 2002, p. 160.
23. Vuylsteke RJCLM, van Leeuwen PAM, Borgstein PJ, Gietema HA, Statius Muller MG, van Diest PJ, et al. The area of metastasis in the sentinel lymph node of stage I or II melanoma patients: is it a predictor for additional positive lymph nodes? In: Kitajima M, Thompson JF (editors): Proceedings of the Third International Sentinel Node Congress, Yokohama, Japan, 2002, p. 160.
24. Cochran AJ. Melanoma metastases through the lymphatic system. Surg Clin North Am 2000; 80:1683-1693.
25. Starz H, Balda BR, Kramer KU, Buchels H, Wang H. A micromorphometry-based concept for routine classification of sentinel lymph node metastases and its clinical relevance for patients with melanoma. Cancer 2001; 91:2110-2121.
26. Cochran AJ, Morton DL, Stern S, Lana AM, Essner R, Wen DR. Sentinel lymph nodes show profound downregulation of antigen-presenting cells of the paracortex: implications for tumor biology and treatment. Mod Pathol 2001; 14:604-608.
27. Cochran AJ, Roberts A, Wen D-R, Huang R-R, Itakura E, Luo F, et al. Update on lymphatic mapping and sentinel node biopsy in the management of patients with melanocytic tumours. Pathology 2004; (in press).
28. Cook MG. Benign melanocytic lesions mimicking melanomas. Pathology 2004; (in press).