Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy

Neurology India

Volumn 52, Issue 2, 2004, Pages 206-209

  Pal, S K ^b   Sharma, K ^b   Pathak, A ^a   Sawhney, I M S ^a   Prabhakar, S ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^b PANJAB UNIVERSITY   (India)

Author keywords

Epilepsy; Idiopathic; PTC taste sensitivity; Symptomatic

Indexed keywords

ANTITHYROID AGENT; PHENYLTHIOUREA; PROPYLTHIOURACIL;

ADULT; ALLELE; ARTICLE; BITTER TASTE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE CLASSIFICATION; ELECTROENCEPHALOGRAPHY; EPILEPSY; FEMALE; GENE FREQUENCY; GEOGRAPHIC DISTRIBUTION; HUMAN; IDIOPATHIC DISEASE; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; POPULATION DISTRIBUTION; SENSITIVITY ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SYMPTOMATOLOGY; TASTE ACUITY; ADOLESCENT; CASE CONTROL STUDY; PATHOPHYSIOLOGY; PERCEPTIVE THRESHOLD; TASTE;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; EPILEPSY; FEMALE; HUMANS; MALE; PHENYLTHIOUREA; SENSORY THRESHOLDS; TASTE;

EID: 4344603729     PISSN: 00283886     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Hulse F. The Human Species. New York: Random House 1963.
2. Mourant AE, Kopec AC, Domaniewska-Sobczak K. Blood group and disease Oxford: Oxford University Press; 1978.
3. Singh KS, Bhalla V, Kaul V. The biological variations in Indian populations. Delhi: Oxford University Press 1994.
4. Suk V. Cabbage and goiter in carpathian Ruthenia: A contribution to ethnic pathology Anthropologic 1931;9:1-6.
5. Mackenzie CG, Mackenzie JB. Effect of sulfonamides and thioureas on the thyroid gland and basal metabolism. Endocrinology 1943;32:185.
6. Riddel WJB, Wybar KC. Taste of thiouracil and phenylthiocarbamide. Nature 1944;154:669.
7. Harris H, Kalmus H. Genetical differences in taste sensitivity to phenylthiourea and to anti-thyroid substances. Nature 1949;163:878-9.
8. Van Etten CH. Goitrogens. In: Liener IE, (Ed). Toxic constituents of plant food stuffs. New York: Academic Press 1969:103-42.
9. Terry MC. Taste blindness and diabetes in the colored population of Jamaica. J. Hered 1950;41:306-7.
10. Saldanha PH. Apparent pleiotropic effect of genes determining taste thresholds for phenylthiourea. Lancet 1956;271-4.
11. Manlapas FC, Stein AA, Pagliara AS, Apicelli AA, Porter IH, Patterson PR. Phenylthiocarbamide taste sensitivity in cystic fibrosis. J Pediatr 1965;66:8-11.
12. Kitchin FD, Howel-Envas W, Clarke CA, Mc Connell RR, Sheppard PM. PTC taste response and thyroid disease. Brit Med J 1959;1:1069-74.
13. Facchini F, Abbati A, Campagnoni S. Possible relations between sensitivity to phenylthiocarbamide and goiter. Hum Biol 1990;62:545-52.
14. Sheppard TH, Gartler SM. Increased incidence of non-tasters of phenylthiocarbamide among congenital athyreotic cretins. Science 1960;131:929.
15. Fraser GR. Cretinism and taste sensitivity to phenylthiocarbamide. Lancet 1961;280:964-5.
16. Chung CS, Witkop CJ, Henry JL. A genetic study of dental caries with special reference to PTC taste sensitivity. Am J Hum Genet 1964;16:231-45.
17. Sharma K. Genetic epidemiology of epilepsy: A twin study. Neurology India 2004.
18. Commission on classification and terminology of the International League gainst epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989;32:199-208.
19. Harris H, Kalmus H. The measurement of taste sensitivity to PTC. Ann Eugen 1949;15:24-31.
20. Woolf B. On Estimating the relation between blood groups and diseases. Ann Hum Genet 1955;19:251-3.
21. Greene LS. Physical growth and development, neurological maturation and behavioural functioning in two Ecuadorian Andean Communities in which goiter is endemic. II. PTC taste sensitivity and neurological maturation. Am J Phys Anthropol 1974;41:139-52.
22. Hollingsworth DR. Phenylthiourea taste testing in Hiroshima subjects with thyroid disease. J Clin Endocrinol 1963;23:961-3.
23. Brand N. Taste sensitivity and endemic goiter in Israel. Ann Hum Genet 1963;26:321-4.
24. Azevedo EH, Krieger H, Mi MP, Morton NE. PTC taste sensitivity and endemime goiter in Brazil. Am J Hum Genet 1965;17:87-90.
25. De Luca F, Cramarossa L. Phenylthiourea and endemic goiter. Lancet 1965.
26. Mendez de Araujo HM, Salzano FM, Wolf H. New data on the association between PTC and thyroid disease. Human genetik 1972;15:136-44.
27. Kaplan AR, Fischer R., Glanville E. Powell, W. Kamionkowski M, Flesher B Differential taste sensitivities in duodenal and gastric ulcer patients gastroenterology 1964;47:604-9.
28. Delange F, Thilly C, Pourbaix P, Ermans ANN. Treatment of Idjwi islandendemic goiter by iodized oil. In: Stanbury B, (Ed). Endemic Goiter. Washington: Pan American Health Organization Scientific Publication No. 193, WHO; 1969:118-31.
29. Pal SK. Biomedical - Anthropological investigations on epileptics. Ph.D thesis (unpublished) Chandigarh: Panjab University 2002.